Výsledky vyhledávání - "S. H. Ohanian"

Cell-bound C4b resists reduction by reducing agents: analysis by chain structure and by hemolytic activity

Autor: R Ejzemberg, E J Brown, S H Ohanian, C H Hammer, T Borsos

Publikováno v: The Journal of Immunology. 130:2825-2830

EA3H-C4hu treated with 2-mercaptoethanol (MSH) or dithiothreitol (DTT) were analyzed for residual chains and hemolytic activity. MSH treatment resulted in no loss of the chains of C4b and no loss of reactivity with a polyclonal anti-human C4 rabbit a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f2a00e3699375cbb2d4ed9f6ed99b6d3
https://doi.org/10.4049/jimmunol.130.6.2825

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Tumor cell lipid composition and sensitivity to humoral immune killing. II. Influence of plasma membrane and intracellular lipid and fatty acid content

Autor: S I Schlager, S H Ohanian

Publikováno v: The Journal of Immunology. 125:508-517

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63a621838fbca238dfc4945baf6061e0
https://doi.org/10.4049/jimmunol.125.2.508

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In Vivo Immunologic Selection of Proviral Gene Deletion Variants From a Nonproducer Clone

Autor: S. H. Ohanian, C. B. Talmadge, Y. Tanio, J. Hovis, Berton Zbar, G. Dekaban

Publikováno v: JNCI: Journal of the National Cancer Institute. 77:767-775

The mechanism by which tumors recur at sites of injection of retrovirus-infected fibrosarcoma cell lines was investigated. Previously, it was established that tumor recurrences reflect outgrowth of rare cells that lack viral antigens and are suscepti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efdf0e9f1d422236da98dd6ac143913
https://doi.org/10.1093/jnci/77.3.767

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Interaction of Subcomponent Clq and Collagen with Isolated Platelet Membranes in Platelet Aggregation

Autor: E A Suba, G Csákó, S H Ohanian

Publikováno v: Pathophysiology of Haemostasis and Thrombosis. 13:288-293

Human platelet membranes were isolated by the glycerollysis technique. When tested by a turbidimetric method in the presence of fibrinogen and calcium ions, the membrane vesicles exhibited patterns of reactivity to collagen. As with human platelet-ri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f0192c0057636b4a86b322c958085984
https://doi.org/10.1159/000214767

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Evidence for the influence of the initial complement components on the assembly and activity of the membrane attack complex

Autor: M D Boyle, S H Ohanian

Publikováno v: The Journal of Immunology. 124:2824-2827

The failure of functionally purified C5gp to reconstitute the hemolytic complement (C) activity of C5-deficient human serum was studied. The lack of hemolytic activity of C5gp in this system could not be correlated with the failure of EAC1-3hu to bin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c3d78512ef845f36de7eba7bd542cd10
https://doi.org/10.4049/jimmunol.124.6.2824

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Modulation of tumor cell susceptibility to humoral immune killing through chemical and physical manipulation of cellular lipid and fatty acid composition

Autor: S I Schlager, S H Ohanian

Publikováno v: The Journal of Immunology. 125:1196-1200

Line-10 tumor cells cultured for 24 hr in lecithin-rich normal human plasma or with synthetic lecithin showed a 5- to 8-fold increase in their lecithin:sphingomyelin mole ratio without being affected in their total lipid content or cholesterol:phosph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96efeba4000b5a0edea4bd67cbfa8fd1
https://doi.org/10.4049/jimmunol.125.3.1196

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Studies on the terminal stages of antibody-complement-mediated killing of a tumor cell. I. Evidence for the existence of an intermediate, T

Autor: M D, Boyle, S H, Ohanian, T, Borsos

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 116(5)

The mechanism of the terminal steps in the lysis of antibody-sensitized tumor cells by complement (TAC) was studied. It was shown that once complement has reacted, lysis proceeded even in the absence of fluid-phase complement. Transformation of TAC t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9bd8e3ddc9c56c88a47c9d87e0cb13fd
https://pubmed.ncbi.nlm.nih.gov/178793

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Studies on the terminal stages of antibody-complement mediated killing of a tumor cell. III. Effect of membrane active agents

Autor: M D, Boyle, S H, Ohanian, T, Borsos

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 117(1)

A comparison of the events leading from T to dead cell and E to E ghost and hemoglobin was made. Transformation of T to dead cells was inhibitable by EDTA, NaF, histamine, DMSO, cytochalasin B and 3'5' cAMP. Transformation of E to E ghost and hemoglo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::da099d64ba987afe57a5cab37997545b
https://pubmed.ncbi.nlm.nih.gov/932422

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