Zobrazeno 1 - 10
of 62
pro vyhledávání: '"S. H. Bigner"'
Autor:
S. H. Bigner
Publikováno v:
Neuro-Oncology. 1:52-60
Autor:
S. H. Bigner, B. K. A. Rasheed
Publikováno v:
Cancer and Metastasis Reviews. 10:289-299
Multiple genetic changes take place during tumor development and progression. These genetic changes result in inactivation of tumor suppressor genes and activation of proto-oncogenes. Frequent genetic changes observed in gliomas are losses of chromos
Publikováno v:
Histopathology. 34(2)
We have reviewed immunohistochemically 17 paediatric medulloblastomas in order to determine if correlations exist that might be useful in subclassifying these tumours.The patient group included 11 children who had died (mean survival 13 months) and s
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 78(5)
Autor:
J W, Bishop, S H, Bigner, T J, Colgan, M, Husain, L P, Howell, K M, McIntosh, D A, Taylor, M H, Sadeghi
Publikováno v:
Acta cytologica. 42(1)
To compare the performance of liquid-based cell preparations from the AutoCyte PREP system (AutoCyte, Inc., Elon College, North Carolina) with the conventional cervical smear in masked, split-sample, multisite trials.The AutoCyte PREP system utilizes
Autor:
B K, Rasheed, T T, Stenzel, R E, McLendon, R, Parsons, A H, Friedman, H S, Friedman, D D, Bigner, S H, Bigner
Publikováno v:
Cancer research. 57(19)
The PTEN gene, located on 10q23, has recently been implicated as a candidate tumor suppressor gene in brain, breast and prostate tumors. In the present study, 123 brain tumors, including various grades and histological types of gliomas occurring in c
Autor:
H S, Friedman, S P, Johnson, Q, Dong, S C, Schold, B K, Rasheed, S H, Bigner, F, Ali-Osman, E, Dolan, O M, Colvin, P, Houghton, G, Germain, J T, Drummond, S, Keir, S, Marcelli, D D, Bigner, P, Modrich
Publikováno v:
Cancer research. 57(14)
A methylator-resistant human glioblastoma multiforme xenograft, D-245 MG (PR), in athymic nude mice was established by serially treating the parent xenograft D-245 MG with procarbazine. D-245 MG xenografts were sensitive to procarbazine, temozolomide
Autor:
M T, Brown, R E, Coleman, A H, Friedman, H S, Friedman, R E, McLendon, R, Reiman, G J, Felsberg, R D, Tien, S H, Bigner, M R, Zalutsky, X G, Zhao, C J, Wikstrand, C N, Pegram, J E, Herndon, N A, Vick, N, Paleologos, R K, Fredericks, S C, Schold, D D, Bigner
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 2(6)
We aimed to determine the maximum tolerated dose (MTD) of 131I-labeled 81C6 in patients with leptomeningeal neoplasms or brain tumor resection cavities with subarachnoid communication and to identify any objective responses. 81C6 is a murine IgG mono
Autor:
B.K. Ahmed Rasheed, Roger E. McLendon, Kar-Ming Fung, John Q. Trojanowski, Rex C. Bentley, Darell D. Bigner, Henry S. Friedman, S. H. Bigner
Publikováno v:
Journal of neuropathology and experimental neurology. 55(5)
Childhood ependymomas exhibit epidemiologic, anatomic, histologic, and biologic features that distinguish them from other gliomas. Because of their propensity to grow in functionally sensitive regions of the brain, adequate tumor sampling for basic a
Publikováno v:
Genes, chromosomescancer. 15(1)
Loss of heterozygosity at specific chromosomal locations has been taken as evidence of a tumor suppressor gene located in that area. We performed a genomic allelotyping study on 46 childhood brain tumors of different histopathological types in order