Zobrazeno 1 - 10
of 315
pro vyhledávání: '"S. Grubb"'
Autor:
Elisa Galliano, Eleonora Franzoni, Marine Breton, Annisa N Chand, Darren J Byrne, Venkatesh N Murthy, Matthew S Grubb
Publikováno v:
eLife, Vol 13 (2024)
Externí odkaz:
https://doaj.org/article/55f8952da8004630ad0373af9bb4eb43
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 113890- (2024)
Externí odkaz:
https://doaj.org/article/4b08878142bd4685ba6812456aa90a7b
Autor:
Ana Dorrego-Rivas, Matthew S. Grubb
Publikováno v:
Open Biology, Vol 12, Iss 6 (2022)
Olfactory sensory neurons (OSNs) in the olfactory epithelium of the nose transduce chemical odorant stimuli into electrical signals. These signals are then sent to the OSNs' target structure in the brain, the main olfactory bulb (OB), which performs
Externí odkaz:
https://doaj.org/article/f9bebf027281447a97b3866e18834848
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100146- (2020)
Summary: Obtaining electrophysiological recordings and gene expression information from the same neuron (Patch-seq) brings forward a unique opportunity to study the transcriptional correlates of functional properties and vice versa. Here, we provide
Externí odkaz:
https://doaj.org/article/7cbaee99283b4f07be46e69affe7b93e
Publikováno v:
Drug Metabolism and Personalized Therapy. 37:295-303
Objectives Colorectal cancer continues to have one of the highest incidents of occurrence with a rising rate of diagnosis among people under the age of 50. Chemotherapy with irinotecan results in severe gastrointestinal dose-limiting toxicity that is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0f861c9ab274092021a9d404d1ccc49
https://doi.org/10.1515/dmpt-2021-0178
https://doi.org/10.1515/dmpt-2021-0178
Embryonic and postnatal neurogenesis produce functionally distinct subclasses of dopaminergic neuron
Autor:
Elisa Galliano, Eleonora Franzoni, Marine Breton, Annisa N Chand, Darren J Byrne, Venkatesh N Murthy, Matthew S Grubb
Publikováno v:
eLife, Vol 7 (2018)
Most neurogenesis in the mammalian brain is completed embryonically, but in certain areas the production of neurons continues throughout postnatal life. The functional properties of mature postnatally generated neurons often match those of their embr
Externí odkaz:
https://doaj.org/article/58e14dc476a74fd98c4dd40d85a1f906
Autor:
Michael S. Bohnen, Hasan Garan, Veli K. Topkara, Nir Uriel, Christopher S. Grubb, Paolo C. Colombo, Ersilia M. DeFilippis, Shunichi Nakagawa, Gabriel Sayer, Jennifer Haythe, Maryjane Farr, Lauren K. Truby, Yoshifumi Naka, Kelly Axsom, Koji Takeda, Melana Yuzefpolskaya, A. Kleet
Publikováno v:
American Heart Journal. 239:11-18
Objective The objective of this study was to describe the profiles and outcomes of a cohort of advanced heart failure patients on ambulatory inotropic therapy (AIT). Background With the growing burden of patients with end-stage heart failure, AIT is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a30118701383cee25254fb109df660
https://doi.org/10.1016/j.ahj.2021.05.001
https://doi.org/10.1016/j.ahj.2021.05.001
Publikováno v:
Cell Reports, Vol 13, Iss 6, Pp 1233-1245 (2015)
Neurons implement a variety of plasticity mechanisms to alter their function over timescales ranging from seconds to days. One powerful means of controlling excitability is to directly modulate the site of spike initiation, the axon initial segment (
Externí odkaz:
https://doaj.org/article/596be47e16df449e92a56ecdb24a044b
Akademický článek
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Publikováno v:
Frontiers in Cellular Neuroscience, Vol 10 (2016)
The axon initial segment (AIS) is a specialised neuronal compartment involved in the maintenance of axo-dendritic polarity and in the generation of action potentials. It is also a site of significant structural plasticity – manipulations of neurona
Externí odkaz:
https://doaj.org/article/9ba1a217ca9042bb8e0bdefb5d63109a