Zobrazeno 1 - 10
of 325
pro vyhledávání: '"S. Gorelick"'
Autor:
Melinda Wang, Frank Ulrich Weiss, Xiaojia Guo, Thomas Kolodecik, Jan Philipp Bewersdorf, Loren Laine, Markus M. Lerch, Gary Desir, Fred S. Gorelick
Publikováno v:
Pancreatology. 23:158-162
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4363b1ccb3ecdc124b8a2456652ffb08
https://doi.org/10.1016/j.pan.2023.01.001
https://doi.org/10.1016/j.pan.2023.01.001
Autor:
Yasheen Gao, Melinda Wang, Xiaojia Guo, Joanna Hu, Tian-Min Chen, Sade M B Finn, Jill Lacy, John W Kunstman, Charles H Cha, Melena D Bellin, Marie E Robert, Gary V Desir, Fred S Gorelick
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0250539 (2021)
Dysregulated expression of the secretory protein renalase can promote pancreatic ductal adenocarcinoma (PDAC) growth in animal models. We characterized renalase expression in premalignant and malignant PDAC tissue and investigated whether plasma rena
Externí odkaz:
https://doaj.org/article/df608288a0c2416eaf83a695166bb52d
Autor:
Fred S. Gorelick, MD
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 883-884 (2021)
Externí odkaz:
https://doaj.org/article/25311e0b4ca940f085ad989c429004b7
Publikováno v:
Cells, Vol 10, Iss 8, p 2006 (2021)
The survival factor renalase (RNLS) is a recently discovered secretory protein with potent prosurvival and anti-inflammatory effects. Several evolutionarily conserved RNLS domains are critical to its function. These include a 20 aa site that encodes
Externí odkaz:
https://doaj.org/article/ec7c2677d1984edf8445b49281564d7e
Autor:
Fred S. Gorelick, Markus M. Lerch
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 2, Pp 251-262 (2017)
Acute pancreatitis is currently the most common cause of hospital admission among all nonmalignant gastrointestinal diseases. To understand the pathophysiology of the disease and as a potential step toward developing targeted therapies, attempts to i
Externí odkaz:
https://doaj.org/article/d773f24f48604c4f9eca89186b813085
Autor:
A A Alahmari, B Sreekumar, V Patel, M Ashat, M Alexandre, A K Uduman, E O Akinbiyi, A Ceplenski, C A Shugrue, T R Kolodecik, N Tashkandi, S W Messenger, G E Groblewski, F S Gorelick, E C Thrower
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0197362 (2018)
Clinical studies have shown that cigarette smoking is a dose-dependent and independent risk factor for acute pancreatitis. Cigarette smoke contains nicotine which can be converted to the potent receptor ligand and toxin, NNK [4-(methylnitrosamino)-1-
Externí odkaz:
https://doaj.org/article/fceddc68b3c94d7fb765649dc69fd9e8
Autor:
Scott W. Messenger, Diana D.H. Thomas, Michelle M. Cooley, Elaina K. Jones, Michelle A. Falkowski, Benjamin K. August, Luis A. Fernandez, Fred S. Gorelick, Guy E. Groblewski
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 6, Pp 695-709 (2015)
Background & Aims: Pancreatic acinar cells have an expanded apical endosomal system, the physiologic and pathophysiologic significance of which is still emerging. Phosphatidylinositol-3,5-bisphosphate [PI(3,5)P2] is an essential phospholipid generate
Externí odkaz:
https://doaj.org/article/a4bac26515624536882f3876d6bc9b12
Autor:
Fred S. Gorelick, Melinda Wang
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Ketamine and xylazine (Ket/Xyl) are anesthetic agents that target neural pathways and are commonly used in combination in mouse studies. Since neural pathways can modulate acute pancreatitis severity, we asked if Ket/Xyl affect disease severity. C57B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002f3c2676896a89124680b9af3f1c3b
https://doi.org/10.1152/ajpgi.00023.2021
https://doi.org/10.1152/ajpgi.00023.2021
Autor:
Fred S. Gorelick, Melinda Wang
Publikováno v:
Digestive diseases and sciences, vol 67, iss 7
Dig Dis Sci
Dig Dis Sci
BACKGROUND: Serum estradiol levels in severe acute injury are correlated with in hospital mortality. In acute pancreatitis, serum estradiol levels are strong predictors of disease severity. Studies of whether changes in estradiol levels play a causat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef638110b3cc72dfb8e6adb8671e6e8f
https://escholarship.org/uc/item/3fp5m57r
https://escholarship.org/uc/item/3fp5m57r
Identification of Two Forms of Human Plasma Renalase, and Their Association With All-Cause Mortality
Autor:
Shang-Lin Chung, Fred S. Gorelick, Charles Cha, Aldo J. Peixoto, Gary V. Desir, Xiaojia Guo, Elizabeth S. Gromisch, Susan T. Crowley, Robert Safirstein, J. Testani, Veena Rao, John J. Chang, Harriet M. Kluger
Publikováno v:
Kidney International Reports
Kidney International Reports, Vol 5, Iss 3, Pp 362-368 (2020)
Kidney International Reports, Vol 5, Iss 3, Pp 362-368 (2020)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a3e9abf19ab4936e67aa1e35b0ba5d
https://doi.org/10.1016/j.ekir.2019.12.002
https://doi.org/10.1016/j.ekir.2019.12.002