Zobrazeno 1 - 10
of 505
pro vyhledávání: '"S. Goodin"'
Autor:
Eun Jung Kim, Caressa Chen, Rebecca Gologorsky, Ana Santandreu, Alonso Torres, Nathan Wright, Mark S. Goodin, Jarrett Moyer, Benjamin W. Chui, Charles Blaha, Paul Brakeman, Shant Vartanian, Qizhi Tang, H. David Humes, William H. Fissell, Shuvo Roy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract The definitive treatment for end-stage renal disease is kidney transplantation, which remains limited by organ availability and post-transplant complications. Alternatively, an implantable bioartificial kidney could address both problems whi
Externí odkaz:
https://doaj.org/article/0d211e11b47246acb10abcd7f2c4c868
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0285599 (2023)
ObjectiveTo explore and describe the basis and implications of genetic and environmental susceptibility to multiple sclerosis (MS) using the Canadian population-based data.BackgroundCertain parameters of MS-epidemiology are directly observable (e.g.,
Externí odkaz:
https://doaj.org/article/5e560e8ecc2e4fd2a2ac46ebdf54b2dd
Autor:
Douglas S. Goodin
Multiple Sclerosis (MS) is generally understood to be an inflammatory autoimmune disease of the central nervous system. While we still are not certain of the root cause of MS, research results suggest that unknown environmental factors and the presen
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-15 (2021)
Abstract Background To study the accumulation of MS-risk resulting from different combinations of MS-associated conserved-extended-haplotypes (CEHs) of the MHC and three non-MHC “risk-haplotypes” nearby genes EOMES, ZFP36L1, and CLEC16A. Many hap
Externí odkaz:
https://doaj.org/article/d7b293af90aa4ee59890a42977371986
Autor:
Douglas S. Goodin, Jorge R. Oksenberg, Venceslas Douillard, Pierre-Antoine Gourraud, Nicolas Vince
Publikováno v:
PLoS ONE, Vol 16, Iss 8 (2021)
Objective To explore the nature of genetic-susceptibility to multiple sclerosis (MS) in African-Americans. Background Recently, the number of genetic-associations with MS has exploded although the MS-associations of specific haplotypes within the maj
Externí odkaz:
https://doaj.org/article/4f7643d48d8340ca89c6f42189c41eea
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0246157 (2021)
ObjectiveTo understand the nature of genetic and environmental susceptibility to multiple sclerosis (MS) and, by extension, susceptibility to other complex genetic diseases.BackgroundCertain basic epidemiological parameters of MS (e.g., population-pr
Externí odkaz:
https://doaj.org/article/ae64381b0cbc4d49a6a6044150a52320
Autor:
Kiyotaka Fukamachi, Anthony R. Polakowski, Mark S. Goodin, David J. Horvath, Barry D. Kuban, Christine R. Flick, Michael S. Showalter, Jamshid H. Karimov
Publikováno v:
ASAIO journal (American Society for Artificial Internal Organs : 1992). 68(8)
We are developing a universal, advanced ventricular assist device (AVAD) with automatic pressure regulation suitable for both left and right ventricular support. The primary goal of this computational fluid dynamics (CFD) study was to analyze the biv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6635fdcf0f95865396a7fc2d9014abc
https://pubmed.ncbi.nlm.nih.gov/34772847
https://pubmed.ncbi.nlm.nih.gov/34772847
Autor:
David J. Horvath, Mark S. Goodin, Kiyotaka Fukamachi, Jamshid H. Karimov, Christine R. Flick, Barry D. Kuban, Anthony R. Polakowski
Publikováno v:
ASAIO Journal. 68:829-838
Cleveland Clinic is developing a continuous-flow total artificial heart (CFTAH). This novel design operates without valves and is suspended both axially and radially through the balancing of the magnetic and hydrodynamic forces. A series of long-term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912bfbaab12fbc54a3caa21f398171cd
https://doi.org/10.1097/mat.0000000000001581
https://doi.org/10.1097/mat.0000000000001581
Autor:
David J. Horvath, Jamshid H. Karimov, Maryam Khelghatibana, Kiyotaka Fukamachi, Barry D. Kuban, Mark S. Goodin, Michael Yaksh
Publikováno v:
ASAIO J
Cleveland Clinic’s continuous-flow total artificial heart (CFTAH) is a double-ended centrifugal blood pump that has a single rotating assembly with an embedded magnet, which is axially and radially suspended by a balance of magnetic and hydrodynami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d2a97aa1d1a1d6288b613514b09e60
https://doi.org/10.1097/mat.0000000000001556
https://doi.org/10.1097/mat.0000000000001556
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0190043 (2018)
To determine the relationship between highly-conserved extended-haplotypes (CEHs) in the major histocompatibility complex (MHC) and MS-susceptibility.Among the ~200 MS-susceptibility regions, which are known from genome-wide analyses of single nucleo
Externí odkaz:
https://doaj.org/article/144c7b22a59c447abbcd2feda5f770da