Zobrazeno 1 - 10 of 114 pro vyhledávání: '"S. Gillings"'
1
Geographical differences in survival of dogs with non-Hodgkin lymphoma treated with a CHOP based chemotherapy protocol
Autor: K. B. Reeds, Heather Wilson-Robles, Jessica Lawrence, Z. M. Wright, C. Saba, Michael O. Childress, S. Gillings, Nikolaos G. Dervisis, Timothy J. Stein, K. R. Vickery, Kristine Burgess, S. Rau, Stephanie E. Schleis, C. J. DeRegis, B. Brugmann, Christine M. Budke, Travis Laver, O. A. Smrkovski, M. Silver, A. Novosad, Janet Lori, G. S. Post, Tasha Miller, Douglas H. Thamm
Publikováno v: Veterinary and Comparative Oncology. 15:1564-1571
Background In humans geographical differences in the incidence and presentation of various cancers have been reported. However, much of this information has not been collected in veterinary oncology. Aim The purpose of this study was to determine if
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9eefd515e6fc715bc00e43562e4cbef0
https://doi.org/10.1111/vco.12302
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2
Geographical differences in survival of dogs with non-Hodgkin lymphoma treated with a CHOP based chemotherapy protocol
Autor: H, Wilson-Robles, C M, Budke, T, Miller, N, Dervisis, A, Novosad, Z, Wright, D H, Thamm, K, Vickery, K, Burgess, M, Childress, J, Lori, C, Saba, S, Rau, M, Silver, G, Post, K, Reeds, S, Gillings, S, Schleis, T, Stein, B, Brugmann, C, DeRegis, O, Smrkovski, J, Lawrence, T, Laver
Publikováno v: Veterinary and comparative oncology. 15(4)
In humans geographical differences in the incidence and presentation of various cancers have been reported. However, much of this information has not been collected in veterinary oncology.The purpose of this study was to determine if a geographic dif
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::939adaf8d2e5e02895e6f6bd5a6b2c96
https://pubmed.ncbi.nlm.nih.gov/28419683
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3
Akademický článek
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4
Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics
Autor: Kathryn Balmanno, Mark Johnson, Ceri M. Wiggins, Annette S. Gillings, Simon J. Cook
Publikováno v: FEBS Journal. 276:6050-6062
The BCL-2 homology domain 3 (BH3)-only protein, B-cell lymphoma 2 interacting mediator of cell death (BIM) is a potent pro-apoptotic protein belonging to the B-cell lymphoma 2 protein family. In recent years, advances in basic biology have provided a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d4bd0797496e0b000d41b3a0e7bc711
https://doi.org/10.1111/j.1742-4658.2009.07329.x
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5
Akademický článek
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6
Akademický článek
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7
Akademický článek
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8
Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics
Autor: Annette S, Gillings, Kathryn, Balmanno, Ceri M, Wiggins, Mark, Johnson, Simon J, Cook
Publikováno v: The FEBS journal. 276(21)
The BCL-2 homology domain 3 (BH3)-only protein, B-cell lymphoma 2 interacting mediator of cell death (BIM) is a potent pro-apoptotic protein belonging to the B-cell lymphoma 2 protein family. In recent years, advances in basic biology have provided a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f1e0ae92862e78ec443f34a93a8c70c1
https://pubmed.ncbi.nlm.nih.gov/19788418
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9
Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell lines
Autor: Annette S. Gillings, Kathryn Balmanno, Simon J. Cook, Simon D. Chell, Shaista Hayat
Publikováno v: International journal of cancer. 125(10)
Mutations in KRAS or BRAF frequently manifest in constitutive activation of the MEK1/2-ERK1/2 signalling pathway. The MEK1/2-selective inhibitor, AZD6244 (ARRY-142886), blocks ERK1/2 activation and is currently undergoing clinical evaluation. Tumour
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edcbf314a3bc786d26f210af01b5cba9
https://pubmed.ncbi.nlm.nih.gov/19637312
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10
Colorectal cancer cells with the BRAF(V600E) mutation are addicted to the ERK1/2 pathway for growth factor-independent survival and repression of BIM
Autor: Julie A Wickenden, Kathryn Balmanno, Catrin Pritchard, Annette S. Gillings, S D Chell, Catherine Newson, M Austin, Mark Johnson, Hong Jin, Simon J. Cook
Publikováno v: Oncogene. 27(57)
The RAF-mitogen-activated protein kinase kinase 1/2-extracellular signal-regulated kinase 1/2 (RAF-MEK1/2-ERK1/2) pathway is activated in many human tumours and can protect cells against growth factor deprivation; however, most such studies have reli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5b702d1182b0ebad3a2d6d9ebf3761
https://pubmed.ncbi.nlm.nih.gov/18806830
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