Výsledky vyhledávání

The Secrets of Transfection in Serumfree Suspension Culture

Autor: M. Henke, N. Di Maiuta, S. Geisse, B. Ten Buren

Publikováno v: Animal Cell Technology Meets Genomics ISBN: 9781402027918

Expression of recombinant proteins using mammalian expression systems is still considered to be costly, tedious and labour-intensive, and thus disadvantageous to high throughput applications. However, a breakthrough in the rapid generation of recombi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b94a4538cc9fb29df85ea50b75ae434
https://doi.org/10.1007/1-4020-3103-3_73

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Pancreatic beta-cell K(ATP) channel activity and membrane-binding studies with nateglinide: A comparison with sulfonylureas and repaglinide

Autor: S, Hu, S, Wang, B, Fanelli, P A, Bell, B E, Dunning, S, Geisse, R, Schmitz, B R, Boettcher

Publikováno v: The Journal of pharmacology and experimental therapeutics. 293(2)

Nateglinide (A-4166) is an amino acid derivative with insulinotrophic action in clinical development for treatment of type 2 diabetes. The aim of this study was to determine whether nateglinide's interaction at the K(ATP) channel/sulfonylurea recepto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::81099ad377f943b75fa6cc2189fac99d
https://pubmed.ncbi.nlm.nih.gov/10773014

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Protein expression in mammalian and insect cell systems

Autor: S, Geisse, H P, Kocher

Publikováno v: Methods in enzymology. 306

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::194f17994e4a186cf77594b57a8c8256
https://pubmed.ncbi.nlm.nih.gov/10432446

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Recombinant human [Cys281]insulin-like growth factor-binding protein 2 inhibits both basal and insulin-like growth factor I-stimulated proliferation and collagen synthesis in fetal rat calvariae

Autor: J H, Feyen, D B, Evans, C, Binkert, G F, Heinrich, S, Geisse, H P, Kocher

Publikováno v: The Journal of biological chemistry. 266(29)

It is recognized that insulin-like growth factors (IGFs) are bound to specific high-affinity insulin-like growth factor-binding proteins (IGFBPs). The role of IGFBPs in bone metabolism is not well established. The effect of recombinant human [Cys281]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8fb873f0ec406251cc032f421ad0023f
https://pubmed.ncbi.nlm.nih.gov/1717466

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Purification and characterization of natural human interleukin-3

Autor: G, Zenke, N A, Lokker, U, Strittmatter, B, Fagg, S, Geisse, G, Huber-Wegmann, H P, Kocher

Publikováno v: Lymphokine and cytokine research. 10(4)

The human interleukin-3 gene was cloned in 1986 and the biochemical and biological properties of recombinant human interleukin-3 (rhuIL-3) protein were described. In this report we compare rhuIL-3 with nonrecombinant, natural huIL-3, purified from th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::12a06c7b22ca573374bfe0573fd04590
https://pubmed.ncbi.nlm.nih.gov/1932378

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Cyclosporin A and FK-506 both affect DNA binding of regulatory nuclear proteins to the human interleukin-2 promoter

Autor: G, Baumann, S, Geisse, M, Sullivan

Publikováno v: The New biologist. 3(3)

The structurally unrelated immunosuppressive drugs cyclosporin A (Sandimmun) and FK-506 both interfere with the process of T-cell proliferation by blocking the transcription of the T-cell growth factor interleukin-2 (IL-2). Here we demonstrate that t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f51898c704a73b74416c4146d5f6f37d
https://pubmed.ncbi.nlm.nih.gov/1715185

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Akademický článek

Results from the search for dark matter in the Milky Way with 9 years of data of the ANTARES neutrino telescope

Autor: A. Albert, M. André, M. Anghinolfi, G. Anton, M. Ardid, J.-J. Aubert, T. Avgitas, B. Baret, J. Barrios-Martí, S. Basa, V. Bertin, S. Biagi, R. Bormuth, S. Bourret, M.C. Bouwhuis, R. Bruijn, J. Brunner, J. Busto, A. Capone, L. Caramete, J. Carr, S. Celli, T. Chiarusi, M. Circella, J.A.B. Coelho, A. Coleiro, R. Coniglione, H. Costantini, P. Coyle, A. Creusot, A. Deschamps, G. De Bonis, C. Distefano, I. Di Palma, C. Donzaud, D. Dornic, D. Drouhin, T. Eberl, I. El Bojaddaini, D. Elsässer, A. Enzenhöfer, I. Felis, L.A. Fusco, S. Galatà, P. Gay, S. Geißelsöder, K. Geyer, V. Giordano, A. Gleixner, H. Glotin, T. Grégoire, R. Gracia Ruiz, K. Graf, S. Hallmann, H. van Haren, A.J. Heijboer, Y. Hello, J.J. Hernández-Rey, J. Hößl, J. Hofestädt, C. Hugon, G. Illuminati, C.W. James, M. de Jong, M. Jongen, M. Kadler, O. Kalekin, U. Katz, D. Kießling, A. Kouchner, M. Kreter, I. Kreykenbohm, V. Kulikovskiy, C. Lachaud, R. Lahmann, D. Lefèvre, E. Leonora, M. Lotze, S. Loucatos, M. Marcelin, A. Margiotta, A. Marinelli, J.A. Martínez-Mora, A. Mathieu, R. Mele, K. Melis, T. Michael, P. Migliozzi, A. Moussa, C. Mueller, E. Nezri, G.E. Păvălaş, C. Pellegrino, C. Perrina, P. Piattelli, V. Popa, T. Pradier, L. Quinn, C. Racca, G. Riccobene, K. Roensch, A. Sánchez-Losa, M. Saldaña, I. Salvadori, D.F.E. Samtleben, M. Sanguineti, P. Sapienza, J. Schnabel, F. Schüssler, T. Seitz, C. Sieger, M. Spurio, Th. Stolarczyk, M. Taiuti, Y. Tayalati, A. Trovato, M. Tselengidou, D. Turpin, C. Tönnis, B. Vallage, C. Vallée, V. Van Elewyck, D. Vivolo, A. Vizzoca, S. Wagner, J. Wilms, J.D. Zornoza, J. Zúñiga

Publikováno v: Physics Letters B, Vol 769, Iss C, Pp 249-254 (2017)

Using data recorded with the ANTARES telescope from 2007 to 2015, a new search for dark matter annihilation in the Milky Way has been performed. Three halo models and five annihilation channels, WIMP+WIMP→bb¯,W+W−,τ+τ−,μ+μ− and νν¯, w

Externí odkaz: https://doaj.org/article/21805857f530496c979570154d6b55ba

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