Zobrazeno 1 - 5
of 5
pro vyhledávání: '"S. G. Woolfrey"'
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 19:1047-1059
This study describes a highly sensitive, solid-phase extraction-HPLC/MS/MS assay for cyclophosphamide in human plasma, with a minimum quantifiable level of 0.025 μg mL−1. Plasma samples (0.5 mL) we...
Autor:
P. A. Fox, J Rogers, G F Lockwood, Dennis Greenslade, K Lasher, H. Thysell, Dennis Lendrem, S. G. Woolfrey, J Hegbrant
Publikováno v:
Journal of Pharmacy and Pharmacology. 47:651-655
This study was designed to test a proposed dose modification for intravenous milrinone in congestive heart failure patients (CHF, NYHA I-II) with either moderate or severe renal impairment. All the patients were administered an intravenous loading do
Publikováno v:
Journal of pharmacokinetics and pharmacodynamics. 28(5)
The purpose of this study was to examine how best to incorporate plasma samples which fall below an assay's lower limit of quantification into the process of toxicokinetic data modeling. Secondly to establish what proportion of data can be below the
Publikováno v:
Journal of pharmacokinetics and pharmacodynamics. 28(2)
The purpose of this study was to evaluate whether mixed effects modeling (MEM) performs better than either noncompartmental or compartmental naïve pooled data (NPD) analysis for the interpretation of single sample per subject pharmacokinetic (PK) da
Publikováno v:
Journal of Pharmacy and Pharmacology. 41:579-581
This work has examined the effect of Miglyol 812 oil and its composite fatty acids on the oral absorption of propranolol with reference to its intravenous (i.v.) pharmacokinetics. Propranolol hydrochloride, spiked with 4-3 H labelled compound, was ad