A combinatorial library of substituted 3-sulfonyl-2-imino-1,2-dihydro-5H-dipyrido[1,2-a:2’,3’-d]pyrimidin-5-ones and their anticancer activities

Autor: S. G. Pilyo, B. A. Demydchuk, V. S. Moskvina, O. V. Shablykina, V. S. Brovarets

Publikováno v: Biopolymers and Cell. 38:242-256

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2de4ede9781543d2970aab2c6509cd5e
https://doi.org/10.7124/bc.000a7b

Synthesis and Antitumor Activity of 5-Phenyl-1,3-thiazole-4-sulfonamide Derivatives

Autor: A. O. Severin, S. G. Pilyo, L. M. Potikha, V. S. Brovarets

Publikováno v: Russian Journal of General Chemistry. 92:174-184

Abstract A method for the synthesis of 5-phenyl-1,3-thiazole-4-sulfonyl chloride was developed based on the cyclization of ethyl 2-{[1-(benzylsulfanyl)-2-oxo-2-phenylethyl]amino}-2-oxoacetate obtained from available reagents under the action of the L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6cb082c177a2aacddcd49797218d6bf6
https://doi.org/10.1134/s1070363222020062

Design, Synthesis, and Xanthine Oxidase Inhibitory Activity of 4-(5-Aminosubstituted-4-cyanooxazol-2-yl)benzoic Acids.

Autor: Kobzar O; Department of Bioorganic Mechanisms, V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine, Academika Kukharya Str. 1, 02094, Kyiv, Ukraine., Beiko A; Department of Bioorganic Mechanisms, V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine, Academika Kukharya Str. 1, 02094, Kyiv, Ukraine., Merzhyievskyi D; Department of Chemistry of Bioactive Nitrogen-Containing Heterocyclic Bases, V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine, Academika Kukharya Str. 1, 02094, Kyiv, Ukraine.; Laboratory of Environmental Toxicology, National Institute of Chemical Physics and Biophysics, Akadeemia tee 23, 12618, Tallinn, Estonia., Shablykin O; Department of Chemistry of Bioactive Nitrogen-Containing Heterocyclic Bases, V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine, Academika Kukharya Str. 1, 02094, Kyiv, Ukraine., Brovarets V; Department of Chemistry of Bioactive Nitrogen-Containing Heterocyclic Bases, V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine, Academika Kukharya Str. 1, 02094, Kyiv, Ukraine., Tanchuk V; Department of Bioorganic Mechanisms, V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine, Academika Kukharya Str. 1, 02094, Kyiv, Ukraine., Vovk A; Department of Bioorganic Mechanisms, V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine, Academika Kukharya Str. 1, 02094, Kyiv, Ukraine.

Publikováno v: ChemMedChem [ChemMedChem] 2024 Nov 04; Vol. 19 (21), pp. e202400478. Date of Electronic Publication: 2024 Sep 17.

Recyclization of 5-Amino- oxazoles as a Route to new Functionalized Heterocycles (Developments of V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the NAS of Ukraine).

Autor: Shablykin OV; Department of chemistry of bioactive nitrogen-containing heterocyclic bases, V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the NAS of Ukraine, Academician Kukhar str., 1, Kyiv, Ukraine.; Enamine Ltd. (www.enamine.net), Winston Churchill str., 78, Kyiv, Ukraine., Brovarets VS; Department of chemistry of bioactive nitrogen-containing heterocyclic bases, V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the NAS of Ukraine, Academician Kukhar str., 1, Kyiv, Ukraine., Shablykina OV; Department of chemistry of bioactive nitrogen-containing heterocyclic bases, V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the NAS of Ukraine, Academician Kukhar str., 1, Kyiv, Ukraine.; Faculty of Chemistry, Taras Shevchenko National University of Kyiv, Volodymyrska str., 60, Kyiv, Ukraine.

Publikováno v: Chemical record (New York, N.Y.) [Chem Rec] 2024 Feb; Vol. 24 (2), pp. e202300264. Date of Electronic Publication: 2023 Oct 26.

Design, Synthesis, Docking, 2D‐QSAR Modelling, Anticancer and Antioxidant Evaluation of Some New Azo‐Compounds Derivatives and Investigation of Their Fluorescence Properties.

Autor: Hamed, Eman O.¹ (AUTHOR), Elsayed, Doaa A.¹ (AUTHOR), Assy, Mohamed G.¹ (AUTHOR), Shehab, Wesam S.¹ (AUTHOR) wsshehab@zu.edu.eg

Publikováno v: ChemistrySelect. 11/7/2022, Vol. 7 Issue 41, p1-14. 14p.