Zobrazeno 1 - 5
of 5
pro vyhledávání: '"S. G. Moody"'
Publikováno v:
European Journal of Clinical Pharmacology. 38:213-218
443C81 is a synthetic enkephalin thought to act on peripheral opiate receptors. The analgesic, central, cardiovascular and endocrine effects of two i.v. doses of 443C81 were investigated in 12 healthy male volunteers. Its effects were compared with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631f468c4aadb59b26820f0d74b38adc
https://doi.org/10.1007/bf00315018
https://doi.org/10.1007/bf00315018
Publikováno v:
European Journal of Clinical Pharmacology. 34:67-71
We have studied 16 healthy men to evaluate preliminary pharmacodynamics and kinetics of BW443C given by i.v. infusions. Four volunteers received escalating doses at weekly intervals, starting at 0.1 microgram.kg-1 for 60 min and increasing to a maxim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8045882c85e00d2ff43c26248d40a270
https://doi.org/10.1007/bf01061420
https://doi.org/10.1007/bf01061420
Autor:
S. G. Moody, J. O’Grady
Publikováno v:
Drugs for Heart Disease ISBN: 9780412265402
It is more than 50 years since activity attributable to prostaglandins was reported in the literature and almost precisely 50 years since von Euler gave the name ‘prostaglandin’ to an extract of sheep seminal vesicles which stimulated smooth musc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e368e1796beb126448549b916c4243be
https://doi.org/10.1007/978-1-4899-3294-5_10
https://doi.org/10.1007/978-1-4899-3294-5_10
Publikováno v:
Prostaglandins. 29(1)
Following an open pilot study, the effects of repeated oral doses of BW245C, a hydantoin prostaglandin analogue, were studied in man. Six healthy volunteers received 150 micrograms BW245C or placebo 6-hourly for 5 days according to a double blind ran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f403a2df36fc920c9afe7af3e38effd0
https://pubmed.ncbi.nlm.nih.gov/3975430
https://pubmed.ncbi.nlm.nih.gov/3975430
Autor:
S. Hassan, A. Hedges, BJ Whittle, Q. A. Mekki, J O'Grady, L. A.-H. Al-Sinawi, MJ Moti, S. G. Moody, C Burke
The effects of 9 beta-methyl carbacyclin, a chemically stable analogue of epoprostenol (prostacyclin, PGI2) were studied, in comparison with epoprostenol, both in vitro and in vivo in man. In vitro 9 beta-methyl carbacyclin and epoprostenol inhibited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d743bad95a917e02d95a4030219bd68
https://europepmc.org/articles/PMC1463693/
https://europepmc.org/articles/PMC1463693/