Výsledky vyhledávání - "S. G. Miller"

Hyperammonaemia with distal renal tubular acidosis

Publikováno v: Archives of Disease in Childhood. 77:441-444

The case is reported of an infant with hyperammonaemia secondary to severe distal renal tubular acidosis. A clinical association between increased concentrations of ammonia in serum and renal tubular acidosis has not previously been described. In res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29caae9dbfe682e41106fdfde4599537
https://doi.org/10.1136/adc.77.5.441

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A biosynthetic regulated secretory pathway in constitutive secretory cells

Autor: Hsiao-Ping H. Moore, S. G. Miller, R. A. Chavez

Publikováno v: The Journal of Cell Biology

It has frequently been proposed that while the constitutive secretory pathway is present in all cells, the regulated secretory pathway is found only in specialized cells such as neuronal, endocrine, or exocrine types. In this study we provide evidenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49522ab1e7975a9e72b4d4021710093
https://doi.org/10.1083/jcb.133.6.1177

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Post-Golgi membrane traffic: brefeldin A inhibits export from distal Golgi compartments to the cell surface but not recycling

Autor: Hsiao-Ping H. Moore, S. G. Miller, L. Carnell

Publikováno v: The Journal of Cell Biology

Recent studies using the fungal metabolite brefeldin A (BFA) have provided important insights into the dynamics and the organization of the ER/Golgi membrane system. Here we examined the effect of BFA on the functional integrity of the distal part of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c26f64d7389e033e38d336c970e000
http://europepmc.org/articles/PMC2290047

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Regulated and constitutive secretion. Differential effects of protein synthesis arrest on transport of glycosaminoglycan chains to the two secretory pathways

Autor: S. G. Miller, C. Brion, Hsiao-Ping H. Moore

Publikováno v: Journal of Biological Chemistry. 267:1477-1483

Many neural and endocrine cells possess two pathways of secretion: a regulated pathway and a constitutive pathway. Peptide hormones are stored in granules which undergo regulated release whereas other surface-bound proteins are externalized constitut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45f05c4572bfa420666be2af7e68e94f
https://doi.org/10.1016/s0021-9258(18)45970-4

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Reconstitution of constitutive secretion using semi-intact cells: regulation by GTP but not calcium

Autor: S. G. Miller, Hsiao-Ping H. Moore

Publikováno v: The Journal of Cell Biology

Regulated exocytosis in many permeabilized cells can be triggered by calcium and nonhydrolyzable GTP analogues. Here we examine the role of these effectors in exocytosis of constitutive vesicles using a system that reconstitutes transport between the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e4a844cbe2602323dcb0c58b3ec432
https://doi.org/10.1083/jcb.112.1.39

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A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor [see commetns]

Autor: S S, Tian, P, Lamb, A G, King, S G, Miller, L, Kessler, J I, Luengo, L, Averill, R K, Johnson, J G, Gleason, L M, Pelus, S B, Dillon, J, Rosen

Publikováno v: Science (New York, N.Y.). 281(5374)

A nonpeptidyl small molecule SB 247464, capable of activating granulocyte-colony-stimulating factor (G-CSF) signal transduction pathways, was identified in a high-throughput assay in cultured cells. Like G-CSF, SB 247464 induced tyrosine phosphorylat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f0882d99231e42be7e859698f7ce2100
https://pubmed.ncbi.nlm.nih.gov/9687269

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