Zobrazeno 1 - 10
of 40
pro vyhledávání: '"S. G. Hilsenbeck"'
Autor:
A. N. Johnston, W. Bu, S. Hein, S. Garcia, L. Camacho, L. Xue, L. Qin, C. Nagi, S. G. Hilsenbeck, J. Kapali, K. Podsypanina, J. Nangia, Y. Li
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-13 (2018)
Abstract Background Psychiatric medications are widely prescribed in the USA. Many antipsychotics cause serum hyperprolactinemia as an adverse side effect; prolactin-Janus kinase 2 (JAK2)-signal transducer and activator of transcription 5 (STAT5) sig
Externí odkaz:
https://doaj.org/article/46483614e2494602b6125ab1099dae25
Autor:
Daekyu Sun, Elzbieta Izbicka, Sunil Sharma, S. G. Hilsenbeck, Abhishek Sharma, D. D. Von Hoff, B. Windle, Eric Raymond, Hiroshi Soda
Publikováno v:
Annals of Oncology. 8:1063-1074
Summary Background Telomerase is an important enzyme whose activity has been convincingly demonstrated in humans recently. It is required for maintenance of ends of chromosomes (telomeres) during cell division. Since its presence has been selectively
Publikováno v:
Anti-Cancer Drugs. 5:202-206
CPT-11 (irinotecan hydrochloride, 7-ethyl-10-[4-(piperidino)-1-piperidino] carbonyloxy-camptothecin) is a semisynthetic camptothecin derivative developed in Japan. The inhibitory activity of CPT-11 against human tumor colony-forming units from freshl
Publikováno v:
Anti-Cancer Drugs. 3:143-146
2',2'-Difluorodeoxycytidine (LY 188011, Gemcitabine) is a novel pyrimidine antimetabolite with promising activity in preclinical models for leukemia and solid tumors. Phase I clinical trials with the agent are ongoing. In order to better define types
Autor:
K. R. Rabin, J. Wang, A. Tsimelzon, D. Morrison, A. S. Gaikwad, L. Hogan, C. L. Rye, S. G. Hilsenbeck, M. Devidas, N. A. Heerema, A. J. Carroll, G. Basso, W. L. Carrol, D. Bhojwani, PESSION, ANDREA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4094::52b1aa237d37073a61710084ca7d7634
http://hdl.handle.net/11585/76022
http://hdl.handle.net/11585/76022
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(6)
Risk calculations for carrying BRCA1/BRCA2 mutations are based on family history and the age of onset of cancers. However, women may carry these deleterious mutations without a strong family history. Additional criteria for risk estimation would be o
Autor:
S. G. Hilsenbeck, D. D. Von Hoff, John R. MacDonald, Jennifer Marty, Steven D. Weitman, S. G. Eckhardt, E. K. Rowinsky, Lisa A. Hammond, G. Mangold
Publikováno v:
European journal of cancer (Oxford, England : 1990). 36(18)
6-hydroxymethylacylfulvene (HMAF; MGI 114; Irofulven) is a semisynthetic analogue of the toxin illudin S, which is a product of the Omphalotus mushroom. MGI 114 induces cytotoxicity against a broad range of solid tumours in vivo , including the drug-
Autor:
K, Wu, H T, Kim, J L, Rodriquez, D, Munoz-Medellin, S K, Mohsin, S G, Hilsenbeck, W W, Lamph, M M, Gottardis, M A, Shirley, J G, Kuhn, J E, Green, P H, Brown
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(9)
Retinoids have been investigated as potential agents for the prevention and treatment of human cancers. These compounds play an important role in regulating cell growth, differentiation, and apoptosis. 9-cis-Retinoic acid (9cRA) is a naturally occurr