Zobrazeno 1 - 10
of 24
pro vyhledávání: '"S. G. Bowes"'
Autor:
A. Charlett, A. G. Purkiss, L. McHugh, C. J. A. O'Neill, S. M. Dobbs, Malcolm Richardson, R. J. Dobbs, C. Weller, S. G. Bowes
Publikováno v:
Europe PubMed Central
The spouses of a group of aged sufferers have been demonstrated to have multifarious differences relevant to parkinsonism from matched controls, which were difficult to explain by selective mating, learned or reactive behaviour. Could parkinsonism be
Publikováno v:
Acta Neurologica Scandinavica. 87:255-261
Reaction time was studied in 103 subjects with idiopathic parkinsonism and 144 without. Central processing time, as measured by the response to a warning, had a component which could be explained by the presence or absence of parkinsonism, but not by
Autor:
S. G. Bowes, C. Weller, P. W. Nicholson, S. M. Dobbs, C. J. A. O'neill, A. Charlett, A. G. Purkiss, R. J. Dobbs
Publikováno v:
British Journal of Clinical Pharmacology. 35:379-385
1. Stride length is highly relevant to mobility and is sensitive to the effects of levodopa in Parkinsonism. Its selection as the primary outcome criterion allowed comparison of two levodopa/decarboxylase inhibitor formulations using a small number o
Autor:
S. M. Dobbs, S. G. Bowes, C. Weller, A. Charlett, A. A. Deshmukh, C. J. A. O'neill, R. J. Dobbs, J. S. Milledge, P. W. Nicholson
Publikováno v:
British Journal of Clinical Pharmacology. 33:167-178
1. Captopril was evaluated as an adjuvant to diuretic and digoxin therapy in heart failure in old age, using walking ability, minute ventilation and oxygen consumption and plasma atrial natriuretic factor (ANF) concentration as measures of outcome. 2
Publikováno v:
Age and Ageing. 21:189-194
Axial rotation during recumbency was used to quantify the tendency towards parkinsonism with respect to one cardinal sign, brady/hypokinesia. Twenty-four elderly sufferers from idiopathic parkinsonism, their spouses, and 40 control subjects were stud
Publikováno v:
Age and Ageing. 21:389-392
Autor:
C. Weller, A. A. Deshmukh, A. L. Leeman, S. M. Dobbs, C. J. A. O'neill, S. G. Bowes, P. W. Nicholson, R. J. Dobbs, P. K. Clark, A. Charlett
Publikováno v:
British Journal of Clinical Pharmacology. 31:295-304
1. We compare the sensitivity and specificity of chosen outcome criteria in a placebo-controlled, randomised cross-over study of the efficacy of maintenance therapy with the levodopa/carbidopa combination (Sinemet Plus) alone. Patients were character
Autor:
R. Kosik, C. J. A. O'Neill, Andre Charlett, K. Mozol, P. W. Nicholson, A. G. Purkiss, R. J. Dobbs, S. G. Bowes, W. B. Hunt, S. M. Dobbs, C. Weller, C. Kirollos
1. Quantification of the effect on rigidity of its 'activation', by isometric grip, of standardized pressure, of the contralateral hand, was explored. Torque required to move the forearm through a fixed angle of 40 degrees, at a controlled rate of 0.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2242e028f620690c51379e144504897e
https://europepmc.org/articles/PMC2042619/
https://europepmc.org/articles/PMC2042619/
Autor:
W. B. Hunt, S. G. Bowes, A. G. Purkiss, R. J. Dobbs, A. Charlett, C. Kirollos, J. Dickins, G. Faulkner, C. Weller, S. M. Dobbs, P. W. Nicholson, C. J. A. O'Neill
Publikováno v:
European journal of clinical pharmacology. 50(1-2)
Poor specificity of face-value endpoints and the poor sensitivity of gross clinical examination may have militated against demonstrating prophylaxis by selegiline.Objective measures of the four cardinal signs were used as primary outcome criteria in
Autor:
C. J. A. O'Neill, P. W. Nicholson, J. Dickins, M. Henley, S. G. Bowes, S. M. Dobbs, Andre Charlett, R. J. Dobbs
Publikováno v:
Acta neurologica Scandinavica. 87(4)
Sufferers from parkinsonism have difficulty shifting or developing an appropriate mental set. Delayed auditory feedback may, therefore, disrupt their speech more than that of healthy controls. This was the case when 104 subjects with idiopathic parki