Zobrazeno 1 - 10
of 67
pro vyhledávání: '"S. Futterweit"'
Publikováno v:
Journal of the American Society of Nephrology. 8:1276-1282
Hyperglycemia directly contributes to the development of diabetic nephropathy. A high-serum glucose concentration alters intraglomerular hemodynamics and promotes deposition of extracellular matrix in the kidney. Nitric oxide (NO) is a short-lived me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6280c24b51b68f2540cee6a7028466
https://doi.org/10.1681/asn.v881276
https://doi.org/10.1681/asn.v881276
Autor:
H. Trachtman, S. Futterweit, J. Maesaka, C. Ma, E. Valderrama, A. Fuchs, A. A. Tarectecan, P. S. Rao, J. A. Sturman, T. H. Boles, al. et
Publikováno v:
American Journal of Physiology-Renal Physiology. 269:F429-F438
We examined the effect of two endogenous antioxidant agents, taurine and vitamin E, on renal function in experimental diabetes. Male Sprague-Dawley rats, rendered diabetic with streptozocin (STZ), were assigned to one of the following groups: 1) untr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a2774f1e93bcc4da4bb256c18a8453
https://doi.org/10.1152/ajprenal.1995.269.3.f429
https://doi.org/10.1152/ajprenal.1995.269.3.f429
Publikováno v:
Biochemical and Biophysical Research Communications. 199:346-352
High glucose and elevated levels of advanced glycosylation end products (AGEs) exert an antiproliferative effect on cultured mesangial cells. In view of the role of oxygen free radicals in the pathogenesis of diabetic nephropathy, we tested whether t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac621f0bdef37955bc992dbc1ec26348
https://doi.org/10.1006/bbrc.1994.1235
https://doi.org/10.1006/bbrc.1994.1235
Publikováno v:
Hypertension. 17:194-202
Hyperuricemia is present in 20-40% of pediatric and adult patients with essential hypertension. This metabolic abnormality may represent an additional risk factor for the development of cardiovascular disease. Therefore, we performed the following st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f3062aa5e35624cb15551cc7a2dcb5
https://doi.org/10.1161/01.hyp.17.2.194
https://doi.org/10.1161/01.hyp.17.2.194
Publikováno v:
Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 47(3)
Primary focal segmental glomerulosclerosis (FSGS) recurs in nearly 30% of patients who progress to end-stage renal disease and then receive a kidney transplant. A circulating plasma factor has been isolated from these patients that increases glomerul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2bcf5ebda4edab06fe1ac7c0179b0232
https://pubmed.ncbi.nlm.nih.gov/10198566
https://pubmed.ncbi.nlm.nih.gov/10198566
Publikováno v:
International Journal of Molecular Medicine.
Biochemical modification of extracellular matrix (ECM) proteins can alter the function in overlying cells. We tested the hypothesis that metal-catalyzed oxidation of native ECM and individual matrix proteins modulates the activity of inducible nitric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40c260d6c145f3a6c9e7c8084185db8
https://doi.org/10.3892/ijmm.3.3.323
https://doi.org/10.3892/ijmm.3.3.323
Publikováno v:
Research communications in molecular pathology and pharmacology. 100(2)
Nitric oxide (NO) contributes to the alterations in glomerular hemodynamics and extracellular matrix accumulation observed in diabetic nephropathy. High glucose concentrations directly inhibit NO production by rat mesangial cells (RMC). However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12c5e24e1259695de4d4ba71300b1d43
https://pubmed.ncbi.nlm.nih.gov/9667075
https://pubmed.ncbi.nlm.nih.gov/9667075
Publikováno v:
Research communications in molecular pathology and pharmacology. 94(3)
Tubulointerstitial and periglomerular inflammation and fibrosis are important consequences of pyelonephritis. The pathogenesis of these abnormalities is not fully understood. Renal tubular epithelial cells (RTEC) elaborate biologically active materia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::533b88cde463ac8615663ba653c35b9d
https://pubmed.ncbi.nlm.nih.gov/9029669
https://pubmed.ncbi.nlm.nih.gov/9029669
Autor:
H, Trachtman, J C, Chan, W, Chan, E, Valderrama, R, Brandt, P, Wakely, S, Futterweit, J, Maesaka, C, Ma
Publikováno v:
Pediatric research. 40(4)
IgA nephropathy is one of the most common forms of glomerular disease. Nearly 25% of affected patients progress to end-stage renal disease over a 20-25-y follow-up period. IgA-containing immune complexes stimulate oxygen-free radical production by me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::281a5f2cb79865551e2aac403fe01eca
https://pubmed.ncbi.nlm.nih.gov/8888293
https://pubmed.ncbi.nlm.nih.gov/8888293
Publikováno v:
Research communications in molecular pathology and pharmacology. 93(1)
Nitric oxide (NO) is a signalling molecule that is produced by mesangial cells and renal tubular epithelial (RTE) cells. It plays a role in the regulation of glomerular and tubular function. In renal cells, NO is synthesized by the inducible isoform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a29d058d505679e178a0d90cb8644bc6
https://pubmed.ncbi.nlm.nih.gov/8865371
https://pubmed.ncbi.nlm.nih.gov/8865371