Zobrazeno 1 - 10
of 153
pro vyhledávání: '"S. Franchi-Micheli"'
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 18:141-150
We investigate the role of resting tension on thrombin (THR) induced relaxation of guinea-pig tracheas precontracted with acetylcholine (ACh). Isometric contractions of isolated guinea-pig tracheas were recorded at 4 and 6 g resting tension; and ACh
Autor:
Miriam Cantore, Paola Failli, Marcella Pisanello, Luca Mazzetti, S. Franchi-Micheli, M. Ciuffi, Laura Raimondi, Gabriella Pagliai
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 71:59-68
Several corneal pathologies are characterized by the presence of reactive oxygen species (ROS); therefore, we evaluated the protection afforded by pirenoxine and melatonin to corneal cell culture and whole rabbit cornea from ultraviolet exposure and
Autor:
S. Franchi-Micheli, Lucilla Zilletti, M. Ciuffi, Silvia Nistri, Silvia Quattrone, Luca Mazzetti, Paola Failli, Ruggero Simone
Publikováno v:
British Journal of Pharmacology. 138:707-715
1. Our previously published data indicate that an endogenously produced 5-lipoxygenase metabolite can strongly contract isolated endothelium-preserved rat aortic strips when cyclo-oxygenase isoenzymes are inhibited. Therefore, we decided to investiga
Autor:
S. Franchi-Micheli, Luca Mazzetti, Paola Failli, Lucilla Zilletti, C. Ruocco, Fabio Marra, M. Ciuffi, Lisa Giovannelli
Publikováno v:
British Journal of Pharmacology. 134:596-602
We investigated the effect of the NO-donor S-nitroso-N-acetyl-DL-penicillamine (SNAP) on cardiomyocytes isolated from control normotensive Wistar Kyoto (WKY) and spontaneously hypertensive (SHR) rats. Ventricular cardiomyocytes were isolated from SHR
Publikováno v:
British Journal of Pharmacology. 131:1355-1362
Since the role of mechanical stretches in vascular tone regulation is poorly understood, we studied how stretch can influence endothelial tone. Isometric contractions of isolated rat aortic helical strips were recorded. The resting tension was set at
Autor:
Rolando Guidelli, Maria Rosa Moncelli, S. Franchi-Micheli, Paola Failli, Lucilla Zilletti, Silvia Neri, M. Ciuffi
Publikováno v:
Experimental Eye Research. 68:347-359
Oxidative stress is believed to be involved in cataract development. The protective effect of the xanthomatine derivative, pirenoxine, and the 21-aminosteroid U74389F on oxidative insult in mammalian lenses was evaluated in vitro, ex vivo and in vivo
Autor:
Mario Chelli, Mauro Ginanneschi, Francesco Paoletti, Anna Maria Papini, Lucilla Zilletti, M. Ciuffi, Cristina Cellai, S. Franchi-Micheli
Publikováno v:
Pharmacological Research. 38:279-287
The tetrapeptide-Cu(II) complex H-( l -His-Gly) 2 -OH/Cu(II), indicated as L-Cu(II), has been investigated, as compared to the Cu(II) inorganic salt CuSO 4 , for its antioxidative and anti-inflammatory properties under a panel of experimental conditi
Autor:
Sabrina Mugnai, Lucilla Zilletti, Manuela Maurizi, M. Ciuffi, S. Franchi-Micheli, Daniela Bindi
Publikováno v:
British Journal of Pharmacology. 122:1345-1352
1 We studied the effect exerted by hr-interleukin-1α (IL-1α) on responsiveness of alveolar macrophages (AM) from naive and sensitized guinea-pigs, through O2-. production (by ferricytochrome C reduction), platelet-activating factor (PAF) release (b
Publikováno v:
Biochemical Pharmacology. 52:97-103
Variations of lipid peroxidation and arachidonic acid (AA) metabolism products were found when experimental subarachnoid hemorrhage or ischemia and reperfusion were performed in an animal brain model. In a previous study, we showed that hemoglobin (H
Publikováno v:
British Journal of Pharmacology. 115:389-394
1. In sensitized guinea-pigs, the effects of gamma-aminobutyric acid (GABA) and GABAmimetic drugs have been investigated on tracheal segments contracted by cumulative application of an allergen (ovoalbumin, OA) and on serosal mast cells. The same dru