Výsledky vyhledávání - "S. F. Hobbiger"

Pharmacokinetics of 619C89, a novel neuronal sodium channel inhibitor, in acute stroke patients after loading and discrete maintenance infusions

Autor: I. J. Fraser, Keith W. Muir, John Posner, M. W. Lunnon, S. F. Hobbiger, Z. Hussein, Kennedy R. Lees

Publikováno v: British Journal of Clinical Pharmacology. 41:505-511

1. This was a multi-centre, placebo controlled, randomized, dose-escalating design study in which five dosing regimens of 619C89/placebo were evaluated in 48 stroke patients. Loading infusions of 0.5, 1, 1.5, 2 and 2.5 mg kg-1 over 1 h were followed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5036617c89b4b675c6d6395e00b1ef38
https://doi.org/10.1046/j.1365-2125.1996.03625.x

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The Tolerability, Pharmacokinetics and Pharmacodynamics of Increasing Intravenous Doses of 619C89, a Novel Compound for the Acute Treatment of Stroke, in Healthy Volunteers

Autor: John Posner, A. J. Mercer, Z. Hussein, R. J. Lamb, S. F. Hobbiger

Publikováno v: Annals of the New York Academy of Sciences. 765:324-326

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ff72e0e06e71cde9136e44e38935e7
https://doi.org/10.1111/j.1749-6632.1995.tb16603.x

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