Zobrazeno 1 - 10
of 15
pro vyhledávání: '"S. F. Francom"'
Publikováno v:
Clinical Experimental Allergy. 21:583-587
Summary We examined unilaterality of obstruction after acute bilateral nasal allergen provocation in two groups of pollen-sensitive volunteers studied out of season. One group was challenged on one occasion with a threshold allergen dose and on anoth
Autor:
J C, Fleishaker, L K, Pearson, D W, Knuth, B, Gomez-Mancilla, S F, Francom, M J, McIntosh, S, Freestone, N E, Azie
Publikováno v:
International journal of clinical pharmacology and therapeutics. 37(10)
The objectives of this study were to characterize the safety, tolerability and pharmacokinetics of a single, oral dose of PNU-142633F escalating over the range of 1.0 mg to 100 mg (free base equivalents).This was a randomized, double-blind, single-do
Publikováno v:
Transplantation. 58(10)
Publikováno v:
The Journal of laboratory and clinical medicine. 123(2)
The purpose of this study was to evaluate the effects of phlebotomy of 500 or 750 ml of whole blood followed by isovolemic hemodilution or autologous transfusion on hemodynamic, hematologic, and biochemical parameters in healthy subjects. Four groups
Publikováno v:
Rhinology. 31(4)
Acute nasal allergen challenge produces airway obstruction which varies in amount and timing with the allergen dose delivered. To see whether different mechanisms might contribute variably to mucosal swelling with different amounts of allergen, we ch
Publikováno v:
Journal of clinical pharmacology. 33(9)
The authors compared the effect of several doses an oral corticosteroid on symptom profile and severity in ragweed hay fever. Thirty-one patients were randomized to receive 0, 6, 12, or 24 mg methylprednisolone (Medrol Tablets [MP], Upjohn, Kalamazoo
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 14(7)
Repeated sampling for measurement of venous blood levels of hemoglobin, hematocrit, plasma hemoglobin, potassium and ibuprofen with a novel method of phlebotomy, the double stopcock technique (DST), was compared to heparin lock (HPL), Angiocath with
Publikováno v:
Dermatology (Basel, Switzerland). 184(1)
The ability to modify skin injury due to ultraviolet light (UVB) by the nonsteroidal anti-inflammatory drugs (NSAIDs) oral ibuprofen (IB) or indomethacin (IN) plus topical betamethasone dipropionate (BD) was studied in 24 subjects in this open-label,
Publikováno v:
Antimicrobial agents and chemotherapy. 34(12)
In this study, local and systemic tolerance and pharmacokinetics of trospectomycin sulfate in human beings were evaluated for the first time. Trospectomycin sulfate (U-63,366F; trospectomycin) or sterile saline was administered to 96 healthy male vol
Publikováno v:
International journal of clinical pharmacology, therapy, and toxicology. 28(9)
Trospectomycin sulfate is a novel aminocyclitol antibiotic. This study evaluated the tolerance and the pharmacokinetics of multiple, intravenous doses of trospectomycin (TRO) in healthy male volunteers. Three groups of 10 volunteers were studied. Eig