Zobrazeno 1 - 10
of 21
pro vyhledávání: '"S. Elizabeth Franks"'
Autor:
S. Elizabeth Franks, Kellsye P. Fabian, Ginette Santiago-Sánchez, Benjamin Wolfson, James W. Hodge
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Immune checkpoint blockade (ICB) therapy, while groundbreaking, must be improved to promote enhanced durable responses and to prevent the development of treatment-refractory disease. Cancer therapies that engage, enable, and expand the antitumor immu
Externí odkaz:
https://doaj.org/article/d1c205af3126416db25719406b38af02
Autor:
Momir Bosiljcic, Rachel A. Cederberg, Melisa J. Hamilton, Nancy E. LePard, Bryant T. Harbourne, Jenna L. Collier, Elizabeth C. Halvorsen, Rocky Shi, S. Elizabeth Franks, Ada Y. Kim, Judit P. Banáth, Mark Hamer, Fabio M. Rossi, Kevin L. Bennewith
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-16 (2019)
Abstract Background Solid tumors produce proteins that can induce the accumulation of bone marrow-derived cells in various tissues, and these cells can enhance metastatic tumor growth by several mechanisms. 4T1 murine mammary tumors are known to prod
Externí odkaz:
https://doaj.org/article/27a7a3ac6dc84010a63536a5241f3077
Publikováno v:
Vaccines, Vol 9, Iss 5, p 509 (2021)
Effective treatment of established tumors requires rational multicombination immunotherapy strategies designed to target all functions of the patient immune system and tumor immune microenvironment. While these combinations build on the foundation of
Externí odkaz:
https://doaj.org/article/f963ddcad4bc425a96cb302b41bb9089
Autor:
S. Elizabeth Franks, John C. Cambier
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
B cell antigen receptor (BCR) signaling is a tightly regulated process governed by both positive and negative mediators/regulators to ensure appropriate responses to exogenous and autologous antigens. Upon naïve B cell recognition of antigen CD79 [t
Externí odkaz:
https://doaj.org/article/48f290c33f794b51942aac04ee9b95c4
Autor:
S. Elizabeth Franks, Ginette S. Santiago-Sanchez, Kellsye P. Fabian, Kristen Solocinski, Paul L. Chariou, Duane H. Hamilton, Joshua T. Kowalczyk, Michelle R. Padget, Sofia R. Gameiro, Jeffrey Schlom, James W. Hodge
Publikováno v:
Cancer Immunology, Immunotherapy.
There is strong evidence that chemotherapy can induce tumor necrosis which can be exploited for the targeted delivery of immuno-oncology agents into the tumor microenvironment (TME). We hypothesized that docetaxel, a chemotherapeutic agent that induc
Publikováno v:
J Immunol
The inositol lipid phosphatases PTEN and SHIP-1 play a crucial role in maintaining B cell anergy and are reduced in expression in B cells from systemic lupus erythematosus and type 1 diabetes patients, consequent to aberrant regulation by miRNA-7 and
Publikováno v:
Vaccines, Vol 9, Iss 509, p 509 (2021)
Vaccines
Vaccines
Effective treatment of established tumors requires rational multicombination immunotherapy strategies designed to target all functions of the patient immune system and tumor immune microenvironment. While these combinations build on the foundation of
Autor:
Brennan J. Wadsworth, Kiersten N Thomas, Kevin L. Bennewith, S. Elizabeth Franks, Natalie S. Firmino, Rachel A. Cederberg, Che-Min Lee, Rocky Shi, Lisa R. Decotret
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Oncoimmunology
article-version (VoR) Version of Record
Oncoimmunology
article-version (VoR) Version of Record
Hypoxia develops in germinal centers (GCs) induced by model antigens; however, it is unknown whether tumor-reactive GCs are also hypoxic. We identified GC hypoxia in lymph nodes (LNs) draining murine mammary tumors and lethally irradiated tumor cells
Publikováno v:
Current Opinion in Immunology. 43:39-45
B cells have emerged as effective targets for therapeutic intervention in autoimmunities in which the ultimate effectors are antibodies, as well as those in which T cells are primary drivers of inflammation. Proof of this principle has come primarily
Autor:
Mark Hamer, Fabio M.V. Rossi, Ada Y. Kim, Judit P. Banáth, Nancy E. LePard, Momir Bosiljcic, Jenna L. Collier, Bryant T. Harbourne, Rocky Shi, Melisa J. Hamilton, S. Elizabeth Franks, Rachel A. Cederberg, Kevin L. Bennewith, Elizabeth C. Halvorsen
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 21, Iss 1, Pp 1-16 (2019)
Breast Cancer Research, Vol 21, Iss 1, Pp 1-16 (2019)
Background Solid tumors produce proteins that can induce the accumulation of bone marrow-derived cells in various tissues, and these cells can enhance metastatic tumor growth by several mechanisms. 4T1 murine mammary tumors are known to produce granu