Interleukin 32 expression in human melanoma

Autor: Helicia Paz, Jennifer Tsoi, Anusha Kalbasi, Catherine S. Grasso, William H. McBride, Dörthe Schaue, Lisa H. Butterfield, Deena M. Maurer, Antoni Ribas, Thomas G. Graeber, James S. Economou

Publikováno v: Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-13 (2019)

Abstract Background Various proinflammatory cytokines can be detected within the melanoma tumor microenvironment. Interleukin 32 (IL32) is produced by T cells, NK cells and monocytes/macrophages, but also by a subset of melanoma cells. We sought to b

Externí odkaz: https://doaj.org/article/d5d7f5fae5e844ecb39f49f1e3b53245

Industrial Component Restoration Using Thermal Spray Technologies

Autor: M. Vardavoulias, S. Economou, G. Papapanos

Publikováno v: Surface Modification Technologies XVIII: Proceedings of the Eighteenth International Conference on Surface Modification Technologies Held in Dijon, France November 15-17, 2004: v. 18 ISBN: 9781003423874

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a5f3d4d65f2596d8f9fd3403f4190fbd
https://doi.org/10.1201/9781003423874-48

Data from Proteasome Inhibition Blocks NF-κB and ERK1/2 Pathways, Restores Antigen Expression, and Sensitizes Resistant Human Melanoma to TCR-Engineered CTLs

Autor: James S. Economou, Ali R. Jazirehi

Adoptive cell transfer (ACT) of ex vivo engineered autologous lymphocytes encoding high-affinity MART-1/HLA-A*0201–specific T-cell receptor (TCR)α/β chains (F5 CTL), densely infiltrate into sites of metastatic disease, mediating dramatic but part

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc670d3d28c6d5a4876650235a5ac0f
https://doi.org/10.1158/1535-7163.c.6535198

Supplementary Figures 1 - 8 from Multifunctional T-cell Analyses to Study Response and Progression in Adoptive Cell Transfer Immunotherapy

Autor: James R. Heath, Antoni Ribas, Begonya Comin-Anduix, James S. Economou, Bartosz Chmielowski, David Baltimore, Owen N. Witte, Alistair J. Cochran, Earl Avramis, Charles Ng, Zhongqi Wu, Richard C. Koya, Thinle Chodon, Ann F. Cheung, Chao Ma

PDF file - 1292K, Study scheme, assay validation, functional changes of patients F5-2 and F5-8.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c88c6ea6e08bff6b02ca1f29de0080d
https://doi.org/10.1158/2159-8290.22529706

Supplementary Figure 5 from Proteasome Inhibition Blocks NF-κB and ERK1/2 Pathways, Restores Antigen Expression, and Sensitizes Resistant Human Melanoma to TCR-Engineered CTLs

Autor: James S. Economou, Ali R. Jazirehi

PDF file, 473KB, NF-κB pathway is hyperactive in the resistant cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c399523d0ea2aedc14b7dba35f3d326
https://doi.org/10.1158/1535-7163.22496230