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Akademický článek

Microwave treatment induced mutations and altered gene expression in Vigna aconitifolia

Autor: R. K. Jangid, R. Sharma, Y. Sudarsan, S. Eapen, G. Singh, A. K. Purohit

Publikováno v: Biologia Plantarum, Vol 54, Iss 4, Pp 703-706 (2010)

Primary leaf explants of aseptically grown seedlings of moth bean [Vigna aconitifolia (Jacq.) Marechal] immersed in water or not were treated in microwave oven (2450 MHz, 800 W cm-2) for 1, 3, 5 and 7 s before culturing. Callusing and shoot emergence

Externí odkaz: https://doaj.org/article/a60493fb11ad4c28b245c62f78875cda

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Akademický článek

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Unraveling the Mechanics of a Repeat-Protein Nanospring: From Folding of Individual Repeats to Fluctuations of the Superhelix

Autor: Marie Synakewicz, Rohan S. Eapen, Albert Perez-Riba, Pamela J. E. Rowling, Daniela Bauer, Andreas Weißl, Gerhard Fischer, Marko Hyvönen, Matthias Rief, Laura S. Itzhaki, Johannes Stigler

Publikováno v: ACS Nano. 16:3895-3905

Tandem-repeat proteins comprise small secondary structure motifs that stack to form one-dimensional arrays with distinctive mechanical properties that are proposed to direct their cellular functions. Here, we use single-molecule optical tweezers to s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c211311a518f267a20b7e6f55240461e
https://doi.org/10.1021/acsnano.1c09162

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Asthma

Autor: Saju S. Eapen, William W. Busse

Publikováno v: Inflammatory Mechanisms in Allergic Diseases ISBN: 9780429134432

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea2661ccc351b77f19b355f635e6a85b
https://doi.org/10.1201/9780429134432-18

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Akademický článek

A comparison of intrathecal dexmedetomidine verses intrathecal fentanyl with epidural bupivacaine for combined spinal epidural labor analgesia

Autor: P K Dilesh, S Eapen, S Kiran, Vivek Chopra

Publikováno v: Journal of Obstetric Anaesthesia and Critical Care, Vol 4, Iss 2, Pp 69-74 (2014)

Context: Combined spinal epidural (CSE) analgesia technique is effective for labor analgesia and various concentrations of bupivacaine and lipophilic opioids like fentanyl have been studied. Dexmedetomidine is a highly selective alpha 2 adrenorecepto

Externí odkaz: https://doaj.org/article/2afd691855b74458b67ebebaf2cf1746

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Akademický článek

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Adverse roles of mast cell chymase-1 in COPD

Publikováno v: European Respiratory Journal. 60:2101431

BackgroundCOPD is the third leading cause of death worldwide. Cigarette smoke (CS)-induced chronic inflammation inducing airway remodelling, emphysema and impaired lung function is the primary cause. Effective therapies are urgently needed. Human chy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02be6617dfa720f036287f1bf387a22b
https://doi.org/10.1183/13993003.01431-2021

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Engineering mono- and multi-valent inhibitors on a modular scaffold

Autor: Aurora Diamante, Piyush K. Chaturbedy, Pamela J. E. Rowling, Janet R. Kumita, Rohan S. Eapen, Stephen H. McLaughlin, Marc de la Roche, Albert Perez-Riba, Laura S. Itzhaki

Here we exploit the simple, ultra-stable, modular architecture of consensus-designed tetratricopeptide repeat proteins (CTPRs) to create a platform capable of displaying both single as well as multiple functions and with diverse programmable geometri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5534199904c39e7df2392d9e5752dca
https://www.repository.cam.ac.uk/handle/1810/313348

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