Zobrazeno 1 - 10 of 227 pro vyhledávání: '"S. E. Yoo"'
1
Docking and 3-D QSAR studies of dual PDE4-PDE7 inhibitors†
Autor: S.-E. Yoo, N. S. Kang, J. H. Song, D. J. Jhon
Publikováno v: Molecular Simulation. 33:1109-1117
Small dual-specificity molecules inhibiting PDE4 and PDE7 can be used to treat inflammatory diseases. To design and synthesize dual PDE4 and PDE7 inhibitors, we carried out the target-based docking and the 3D QSAR study using CoMFA. Three compounds w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b9f4c30ec54f28c2e0f2fd5dc027be2
https://doi.org/10.1080/08927020701630205
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2
Study on the hydrolysis mechanism of phosphodiesterase 4 using molecular dynamics simulations
Autor: S.-E. Yoo, N. S. Kang, C. H. Chae
Publikováno v: Molecular Simulation. 32:369-374
We carried out NPT molecular dynamics simulations in an explicit solvent to better understand the mechanism of cyclic adenosine monophosphates (cAMP) hydrolysis by phosphodiesterase 4 (PDE4) enzyme on atomic details and to obtain information on the d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dfd7ca46359c20403aab1c8597acb1be
https://doi.org/10.1080/08927020600717111
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3
Posttranscriptional mechanisms contribute to osmotic regulation of ANG type 1 receptors in cultured rat renomedullary interstitial cells
Autor: Kathryn Sandberg, Sunghou Lee, Christine Maric, S-E. Yoo, Zheng Wu
Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 290:R44-R49
Previously, we showed that ANG II receptors in cultured rat renomedullary interstitial cells (RMICs) are osmotically regulated ( 19 ). The current study examined the mechanisms underlying this osmotic regulation in RMICs cultured in isoosmotic (300 m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de942ecdfec655f650bad4296e45f0f4
https://doi.org/10.1152/ajpregu.00476.2005
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4
Rapid Screening of Drug Absorption Potential Using the Immobilized Artificial Membrane Phosphatidylcholine Column and Molar Volume
Autor: H. Y. Kim, L. S. Kwon, S. E. Yoo, Chi Ho Yoon, Byung Seop Shin, H. S. Chang, Sun Dong Yoo
Publikováno v: Chromatographia. 60:399-404
The immobilized artificial membrane phosphatidylcholine (IAMPC) chromatography was evaluated for the predictability of oral absorption potential of 40 structurally unrelated drugs. The chromatographic capacity factors (kIAM) were determined as a func
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https://doi.org/10.1365/s10337-004-0410-x
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5
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6
The in vitro pharmacological profile of KR31080, a nonpeptide AT1receptor antagonist
Autor: Sunkyung Lee, S.-E. Yoo, Ki Whan Hong, Chi Dae Kim
Publikováno v: Fundamental & Clinical Pharmacology. 12:64-69
KR31080 (2-butyl-5-methyl-6-(1-oxopyridin-2-yl)-3-[2'-(1H-tetrazol-5-yl] biphenyl-4-yl(methyl(-3H-imidazo(4,5-b(pyridine) is a potent inhibitor of angiotensin type 1 (AT 1 ) receptors in rabbit aorta and human recombinant AT 1 receptors. In the isola
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ca7650fa9961fea7d20fa387b2ccca
https://doi.org/10.1111/j.1472-8206.1998.tb00925.x
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10
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