Zobrazeno 1 - 10
of 116
pro vyhledávání: '"S. E. Humphries"'
Autor:
R. H. Fairoozy, M. Futema, R. Vakili, M. R. Abbaszadegan, S. Hosseini, M. Aminzadeh, H. Zaeri, M. Mobini, S. E. Humphries, A. Sahebkar
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Familial hypercholesterolemia (FH) is an autosomal dominant disorder associated with premature cardiovascular disease (CVD). Mutations in the LDLR, APOB, and PCSK9 genes are known to cause FH. In this study, we analysed the genetic spectrum
Externí odkaz:
https://doaj.org/article/aa3ae7837f854b95941b51bc393ee134
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 7, Pp 1463-1472 (1997)
We studied the determinants of postprandial lipemia in 49 post-coronary-bypass men with low HDL cholesterol (< or = 1.1 mmol/l at screening). The subjects were given a mixed meal containing 63 g fat and 150,000 IU vitamin A. Serum was obtained before
Externí odkaz:
https://doaj.org/article/3712baff936944fb89ae3d8f429074c3
Autor:
R M Fisher, F Mailly, R E Peacock, A Hamsten, M Seed, J S Yudkin, U Beisiegel, G Feussner, G Miller, S E Humphries
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 10, Pp 2104-2112 (1996)
A mutation in the lipoprotein lipase (LPL) gene, resulting in the substitution of asparagine by serine at residue 291 (LPL-S291), was found to occur in young survivors of a myocardial infarction from Sweden, combined hyperlipidemic subjects from the
Externí odkaz:
https://doaj.org/article/9e9ad799dc39406a9eaa5f781db8aed5
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 4, Pp 804-812 (1995)
Alterations in lipoprotein levels are reported to be related to an increased risk of gallstones. Plasma lipid metabolism is regulated by a number of proteins that are polymorphic in the population. The present research was designed to investigate the
Externí odkaz:
https://doaj.org/article/1eabf039ec334466b9e5910880898621
Basis of gene structure and function, Farrow S.M. Molecular analysis of gene structure and function, Brickell P.M. Mechanism of action of peptide hormones, Barker S. Steroid hormone superfamily of receptors, Chatterjee V.K.K., Clifton-Bligh R.J. and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0ca6de826b1565be8734e1f286f4561
https://doi.org/10.1201/9781003076926
https://doi.org/10.1201/9781003076926
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 3, Pp 468-477 (1994)
We report the characterization of a new truncated apolipoprotein (apo) B, originally identified in the plasma of a homozygous proband and three heterozygous family members with hypobetalipoproteinemia. Using Western blotting, the truncated apoB speci
Externí odkaz:
https://doaj.org/article/b2bf9a85ceb4497998dd985698b3d3cc
Autor:
S E, Humphries, J A, Cooper, M, Seed, N, Capps, P N, Durrington, B, Jones, I F W, McDowell, H, Soran, H A W, Neil
Publikováno v:
Atherosclerosis
Background and aims Patients with familial hypercholesterolaemia (FH) have an elevated risk of coronary heart disease (CHD). Here we compare changes in CHD mortality in patients with heterozygous (FH) pre 1992, before lipid-lowering therapy with stat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::788468c0010f2e591ae97481d26025ad
https://pubmed.ncbi.nlm.nih.gov/29751283
https://pubmed.ncbi.nlm.nih.gov/29751283
Autor:
Andrea Baragetti, Alberico L. Catapano, S. E. Humphries, Philippa J. Talmud, Jutta Palmen, Liliana Grigore, Katia Garlaschelli, Giuseppe Danilo Norata
Publikováno v:
International Journal of Cardiology. 223:43-45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d443ef6cb92fa8c226ff874e69e130
https://doi.org/10.1016/j.ijcard.2016.08.164
https://doi.org/10.1016/j.ijcard.2016.08.164
Autor:
Elena Tragni, Giuseppe Danilo Norata, Katia Garlaschelli, P.J. Talmud, Jutta Palmen, Alberico L. Catapano, Liliana Grigore, Andrea Baragetti, Fabio Pellegatta, S. E. Humphries
Publikováno v:
Journal of Internal Medicine. 277:478-487
Introduction Leucocyte telomere length (LTL) is an important determinant of telomere function and cellular replicative capacity. The aim of the present study was to examine prospectively the associations between telomere shortening (TS) and both the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247b45e7c9348e5ac482e1f9335bfff9
https://doi.org/10.1111/joim.12282
https://doi.org/10.1111/joim.12282
Autor:
H. E. Montgomery, R. Marshall, H. Hemingway, S. Myerson, P. Clarkson, C. Dollery, M. Hayward, D. E. Holliman, M. Jubb, M. World, E. L. Thomas, A. E. Brynes, N. Saeed, M. Barnard, J. D. Bell, K. Prasad, M. Rayson, P. J. Talmud, S. E. Humphries
A specific genetic factor that strongly influences human physical performance has not so far been reported, but here we show that a polymorphism in the gene encoding angiotensin-converting enzyme does just that. An ‘insertion’ allele of the gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7415e18cc6da5d1dc29b1dd0b31da45e
https://ora.ox.ac.uk/objects/uuid:2ed0fe3f-9fdc-4865-842b-520a848be493
https://ora.ox.ac.uk/objects/uuid:2ed0fe3f-9fdc-4865-842b-520a848be493