Zobrazeno 1 - 3
of 3
pro vyhledávání: '"S. E. Holwell"'
Anti-tumor and anti-vascular effects of the novel tubulin-binding agent combretastatin A-1 phosphate
Publikováno v:
Anticancer research. 22(6C)
The combretastatins are derived from an African medicinal plant Combretum caffrum (Combretaceae). They have previously been shown to be potent inhibitors of microtubule assembly that cause marked haemorrhagic necrosis in murine subcutaneous tumors. P
Publikováno v:
British Journal of Cancer
Anti-vascular effects of the novel Vinca alkaloid, vinflunine have been investigated in the MAC 15A transplantable murine colon adenocarcinoma model and compared with those induced by the most recently identified clinically useful third generation Vi
Publikováno v:
British Journal of Cancer
The anti-tumour effects and mechanism of action of combretastatin A-4 and its prodrug, combretastatin A-4 disodium phosphate, were examined in subcutaneous and orthotopically transplanted experimental colon tumour models. Additionally, the ability of