Zobrazeno 1 - 10
of 57
pro vyhledávání: '"S. E. Grossberg"'
Autor:
Roberto A. Diez, C Vrech, S Chuppa, E. González, Alejandro Vidal, Marcelo Andrés Kauffman, H H Ferro, Mariana Papouchado, B Odoriz, Aída Sterin-Prync, S E Grossberg
Publikováno v:
International journal of immunopathology and pharmacology. 24(2)
In order to determine whether Blastoferon®, a biosimilar interferon (IFN)- beta 1a formulation, shares epitopes with other known IFN-beta products, a series of neutralization bioassays were performed with a set of well-characterized anti-IFN- beta m
Autor:
J L, Taylor, S E, Grossberg
Publikováno v:
Seminars in oncology. 25(1 Suppl 1)
Various interferon-alpha (IFN-alpha) preparations, either as individual subtypes or natural mixtures, induce or inhibit expression of several other cytokines, as well as cytokine receptors and chemokines. The cytokines and receptors reportedly affect
Publikováno v:
Wisconsin medical journal. 96(8)
Publikováno v:
Seminars in oncology. 24(3 Suppl 9)
Recombinant IFN-alpha2b (Intron A, Schering-Plough Corp, Kenilworth, NJ), derived from Escherichia coli, is currently approved worldwide for the therapy of various cancers and chronic hepatitis B and C. We describe here the purity and identity tests
Autor:
D, Mildvan, Y, Bassiakos, M L, Zucker, N, Hyslop, S E, Krown, H S, Sacks, J, Zachary, J, Paredes, W J, Fessel, F, Rhame, F, Kramer, M A, Fischl, B, Poiesz, K, Wood, R M, Ruprecht, J, Kim, S E, Grossberg, P, Kasdan, P, Bergé, A, Marshak, C, Pettinelli
Publikováno v:
Antiviral therapy. 1(2)
Thirty-four subjects with symptomatic HIV-1 infection, p24 antigenaemia, and CD4 cell counts200/mm3 were randomly assigned to receive treatment with either zidovudine (ZDV) orally, interferon-alpha (IFN-alpha) subcutaneously, or both at respective lo
Publikováno v:
Cancer research. 52(18)
The use of bacterial exotoxins may constitute novel adjuncts to treatment of gastrointestinal tract malignancies. Clostridium difficile toxin A was evaluated for its cytotoxic effect in vitro on 24 human cell lines and strains including carcinomas of
Publikováno v:
Journal of biological response modifiers. 9(1)
CL 246,738 is a synthetic heterocyclic of the acridine class that has immunomodulating, interferon (IFN)-inducing, and antitumor activity by the oral route in mice. We have completed a phase I ascending dose trial to determine the maximum tolerated o
Publikováno v:
Journal of Biological Chemistry. 263:1336-1341
Mouse interferons beta (IFN-beta) and gamma (IFN-gamma) inhibit the differentiation of 3T3-L1 fibroblasts into adipocytes when added to cultures at the time of induction of differentiation. Differentiation, as measured by incorporation of radiolabele
Publikováno v:
Journal of Biological Chemistry. 258:7087-7093
Leucine can be utilized efficiently as a precursor for lipid biosynthesis by adipose tissue, especially in the presence of glucose or glucose and insulin. During the differentiation of 3T3-L1 fibroblasts to adipocytes, the rate of lipid biosynthesis
Autor:
P N Redlich, S E Grossberg
Publikováno v:
The Journal of Immunology. 143:1887-1893
Human IFN-beta (HuIFN-beta) is a biologically potent protein with both antiviral and antiproliferative activities. To understand better its mode of action, a number of murine mAb were developed against a recombinant (serine-17) HuIFN-beta (rHuIFN-bet