Zobrazeno 1 - 10
of 53
pro vyhledávání: '"S. E. Ealick"'
Publikováno v:
Journal of Lipid Research, Vol 25, Iss 8, Pp 791-798 (1984)
Crystals of calcium cholate chloride heptahydrate, CaC24H39O7Cl . 7H2O, are monoclinic, space group P2(1), with a = 11.918(2), b = 8.636(1), c = 15.302(3) A, beta = 97.93(3) degrees, V = 1559.9(8) A3, and Z = 2. A trial structure was obtained by Patt
Externí odkaz:
https://doaj.org/article/9ce78f91a7874356b99c3f936dc847c1
Publikováno v:
Journal of Synchrotron Radiation. 4:128-135
A set of linked software modules has been installed at the A1 station of CHESS, the Cornell High Energy Synchrotron Source, which, with the underlying hardware, allows crystallographic users of the facility to evaluate crystals, collect diffraction i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8c86a7afca070db51ef99589b040c4
https://doi.org/10.1107/s0909049597000204
https://doi.org/10.1107/s0909049597000204
Autor:
M D, Erion, S, Niwas, J D, Rose, S, Ananthan, M, Allen, J A, Secrist, Y S, Babu, C E, Bugg, W C, Guida, S E, Ealick
Publikováno v:
Journal of Medicinal Chemistry. 36:3771-3783
X-ray crystallography and computer-assisted molecular modeling (CAMM) studies aided in the design of a potent series of mammalian purine nucleoside phosphorylase (PNP) inhibitors. Enhanced potency was achieved by designing substituted 9-(arylmethyl)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec92803cbad8face42d1e32fefd7448
https://doi.org/10.1021/jm00076a004
https://doi.org/10.1021/jm00076a004
Publikováno v:
Crystal growthdesign. 9(1)
Approximately 15% (w/w) of human intrinsic factor (IF) is comprised of carbohydrate side chains, making crystallization problematic. In addition, IF is sensitive to proteolysis. To understand the role of these factors in crystallization, we carried o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c40d37561f3bafe19f20138ffd86f76
https://pubmed.ncbi.nlm.nih.gov/19884970
https://pubmed.ncbi.nlm.nih.gov/19884970
Autor:
J A, Secrist, K N, Tiwari, A T, Shortnacy-Fowler, L, Messini, J M, Riordan, J A, Montgomery, S C, Meyers, S E, Ealick
Publikováno v:
Journal of medicinal chemistry. 41(20)
A series of 4'-thio-D-arabinofuranosylpurine nucleosides was prepared and evaluated as potential anticancer agents. The details of a convenient and high-yielding synthesis of the carbohydrate precursor 1-O-acetyl-2,3,5-tri-O-benzyl-4-thio-D-arabinofu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1463c4c94b1f1ddc79344761d61a8197
https://pubmed.ncbi.nlm.nih.gov/9748361
https://pubmed.ncbi.nlm.nih.gov/9748361
Publikováno v:
Proteins. 32(1)
Human methyltransferase (hAT) catalyzes the transfer of an alkyl group from the 6-position of guanine to an active site Cys residue. The physiological role of hAT is the repair of alkylated guanine residues in DNA. However, the repair of methylated o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7d118a46242c09d96308a7284a089af
https://pubmed.ncbi.nlm.nih.gov/9672037
https://pubmed.ncbi.nlm.nih.gov/9672037
Publikováno v:
AIP Conference Proceedings.
In designing a system to collect high quality diffraction data in an efficient manner, both hardware and software must be considered. This work focuses on the data collection software used at CHESS, the Cornell High Energy Synchrotron source, with em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eedfecd43637cdf3a719caad49a1073d
https://doi.org/10.1063/1.54584
https://doi.org/10.1063/1.54584
Autor:
M R, Walter, W J, Cook, B G, Zhao, R P, Cameron, S E, Ealick, R L, Walter, P, Reichert, T L, Nagabhushan, P P, Trotta, C E, Bugg
Publikováno v:
The Journal of biological chemistry. 267(28)
The crystal structure of recombinant human interleukin-4 (rhuIL-4) was initially determined at 3.5-A resolution by multiple isomorphous replacement techniques and subsequently refined to a resolution of 2.35 A by simulated annealing. The final crysta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::644580b1eccfb934e28f50dfb6caa20e
https://pubmed.ncbi.nlm.nih.gov/1400355
https://pubmed.ncbi.nlm.nih.gov/1400355
Publikováno v:
The Journal of biological chemistry. 266(1)
The three-dimensional structure of a sarcoplasmic Ca2(+)-binding protein from the sandworm Nereis diversicolor has been determined at 3.0 A resolution using multiple isomorphous replacement techniques. The NH2-terminal half of the molecule contains o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::14d0f5fec12240ef0e49a9d424aedbd6
https://pubmed.ncbi.nlm.nih.gov/1985922
https://pubmed.ncbi.nlm.nih.gov/1985922
Publikováno v:
The Journal of biological chemistry. 265(23)
The three-dimensional structure of thymidine phosphorylase from Escherichia coli has been determined at 2.8 A resolution using multiple-isomorphous-replacement techniques. The amino acid sequence deduced from the deoA DNA sequence is also reported. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d088c953e8cb4f0ee4d65c0482188b91
https://pubmed.ncbi.nlm.nih.gov/2199449
https://pubmed.ncbi.nlm.nih.gov/2199449