Zobrazeno 1 - 10
of 89
pro vyhledávání: '"S. Dron"'
Autor:
S. Dron
Publikováno v:
Епістемологічні дослідження у філософії, соціальних і політичних науках, Vol 2, Iss 23 (2013)
Визначена структура часу в концепціях Аристотеля та Августина. Визначено ідею аристотелівського поняття «тепер» як поєднуючої ланки м
Externí odkaz:
https://doaj.org/article/ef53d9b295484ecc9e75f8abf7d29a8c
Autor:
Yiyi Zhang, Jacqueline S. Dron, Brandon K. Bellows, Amit V. Khera, Junxiu Liu, Pallavi P. Balte, Elizabeth C. Oelsner, Sami Samir Amr, Matthew S. Lebo, Anna Nagy, Gina M. Peloso, Pradeep Natarajan, Jerome I. Rotter, Cristen Willer, Eric Boerwinkle, Christie M. Ballantyne, Pamela L. Lutsey, Myriam Fornage, Donald M. Lloyd-Jones, Lifang Hou, Bruce M. Psaty, Joshua C. Bis, James S. Floyd, Ramachandran S. Vasan, Nancy L. Heard-Costa, April P. Carson, Michael E. Hall, Stephen S. Rich, Xiuqing Guo, Dhruv S. Kazi, Sarah D. de Ferranti, Andrew E. Moran
Publikováno v:
Circulation. 147:1556-1559
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e8722f2cfbb47dba00e30c605aa07b4
https://doi.org/10.1161/circulationaha.123.064168
https://doi.org/10.1161/circulationaha.123.064168
Publikováno v:
Journal of Clinical Lipidology. 17:87-93
Biallelic pathogenic variants in lipoprotein lipase (LPL) cause familial chylomicronemia syndrome with severe hypertriglyceridemia (HTG), defined as plasma triglycerides (TG)10 mmol/L (885 mg/dL). TG levels in individuals with one copy of a pathogeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5d128591deadcac8dab19af86452d4
https://doi.org/10.1016/j.jacl.2022.11.007
https://doi.org/10.1016/j.jacl.2022.11.007
Autor:
Petko Fiziev, Jeremy McRae, Jacob C. Ulirsch, Jacqueline S. Dron, Tobias Hamp, Yanshen Yang, Pierrick Wainschtein, Zijian Ni, Joshua G. Schraiber, Hong Gao, Dylan Cable, Yair Field, Francois Aguet, Marc Fasnacht, Ahmed Metwally, Jeffrey Rogers, Tomas Marques-Bonet, Heidi L. Rehm, Anne O’Donnell-Luria, Amit V. Khera, Kyle Kai-How Farh
Publikováno v:
medRxiv
We examined 454,712 exomes for genes associated with a wide spectrum of complex traits and common diseases and observed that rare, penetrant mutations in genes implicated by genome-wide association studies confer ∼10-fold larger effects than common
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15dd56c1a31aa4f239fad0b89c32d801
https://doi.org/10.1101/2023.05.01.23289356
https://doi.org/10.1101/2023.05.01.23289356
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35bd108c2beb45cb0f53383690bca1ff
https://doi.org/10.1002/ajmg.b.32933
https://doi.org/10.1002/ajmg.b.32933
Autor:
Jacqueline S. Dron
Publikováno v:
Current opinion in lipidology.
Combined hyperlipidemia is the most common lipid disorder and is strongly polygenic. Given its prevalence and associated risk for atherosclerotic cardiovascular disease, this review describes the potential for utilizing polygenic risk scores for risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c990d3c67b083969cd598e458e2336d
https://pubmed.ncbi.nlm.nih.gov/36602940
https://pubmed.ncbi.nlm.nih.gov/36602940
Autor:
Morgan N. Driver, Sally I-Chun Kuo, Lia Petronio, Deanna Brockman, Jacqueline S. Dron, Jehannine Austin, Danielle M. Dick
Publikováno v:
Frontiers in Psychiatry. 13
IntroductionAs gene identification efforts have advanced in psychiatry, so have aspirations to use genome-wide polygenic information for prevention and intervention. Although polygenic risk scores (PRS) for substance use and psychiatric outcomes are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6179ecacbd211a30dfd696c1663e75c
https://doi.org/10.3389/fpsyt.2022.1025483
https://doi.org/10.3389/fpsyt.2022.1025483
Autor:
Lia Petronio, Bum Chul Kwon, Mary O'Reilly, Kenney Ng, Trish Vosburg, Amit Khera, Lisa Nip, Bang Wong, Niall J. Lennon, Deanna Brockman, Jacqueline S. Dron, Akl C. Fahed, Katherine H. Huang, Andrew Tang
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-20 (2021)
BMC Medical Genomics
BMC Medical Genomics
BackgroundPolygenic scores—which quantify inherited risk by integrating information from many common sites of DNA variation—may enable a tailored approach to clinical medicine. However, alongside considerable enthusiasm, we and others have highli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1589c51e8f41bd42038c15e8fd6ddfcb
https://doaj.org/article/59218b19588f4237b182b1d2355f462d
https://doaj.org/article/59218b19588f4237b182b1d2355f462d
Autor:
Robert A. Hegele, Adam D. McIntyre, Zachary Laksman, Julieta Lazarte, Rafik Tadros, Jason D. Roberts, Jacqueline S. Dron, Anthony Tang, Lorne J. Gula, Allan C. Skanes
Publikováno v:
CJC Open
Polygenic scores incorporating varying numbers of single nucleotide polymorphisms (SNPs) have been demonstrated to exert a prominent role in atrial fibrillation (AF). We sought to compare the relative discriminatory capacities of 2 previously validat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f100febc9308c3a53cae975e87127b98
https://doi.org/10.1016/j.cjco.2021.02.001
https://doi.org/10.1016/j.cjco.2021.02.001
Autor:
Jacqueline S. Dron, Adam D. McIntyre, Stephen W. Scherer, Julieta Lazarte, Emma L. Leach, Robert A. Hegele, Zachary Laksman, Brett Trost, Jason D. Roberts, John F. Robinson, Jian Wang, Peter Leong-Sit, Lorne J. Gula, Allan C. Skanes, Henian Cao, Janet Liew
Publikováno v:
Europace
Aims Atrial fibrillation (AF) is a complex heritable disease whose genetic underpinnings remain largely unexplained, though recent work has suggested that the arrhythmia may develop secondary to an underlying atrial cardiomyopathy. We sought to evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d31aa4c5be86c76668542e574dcfd4ec
https://doi.org/10.1093/europace/euaa421
https://doi.org/10.1093/europace/euaa421