Zobrazeno 1 - 10
of 491
pro vyhledávání: '"S. Dorman"'
Autor:
Clyde A. Campbell, Rodolfo Calderon, Giulia Pavani, Xiaoyi Cheng, Radwa Barakat, Elizabeth Snella, Fang Liu, Xiyu Peng, Jeffrey J. Essner, Karin S. Dorman, Maura McGrail, Paul Gadue, Deborah L. French, Raquel Espin-Palazon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Most gene functions have been discovered through phenotypic observations under loss of function experiments that lack temporal control. However, cell signaling relies on limited transcriptional effectors, having to be re-used temporally and
Externí odkaz:
https://doaj.org/article/3dcd259cad5344e190f688aa08345ae0
Autor:
Xiaoyi Cheng, Radwa Barakat, Giulia Pavani, Masuma Khatun Usha, Rodolfo Calderon, Elizabeth Snella, Abigail Gorden, Yudi Zhang, Paul Gadue, Deborah L. French, Karin S. Dorman, Antonella Fidanza, Clyde A. Campbell, Raquel Espin-Palazon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Uncovering the mechanisms regulating hematopoietic specification not only would overcome current limitations related to hematopoietic stem and progenitor cell (HSPC) transplantation, but also advance cellular immunotherapies. However, genera
Externí odkaz:
https://doaj.org/article/c2136f3074024e3ca14b63136730c55e
Autor:
M De-Lima, P Kebriaei, F Lanza, C Cho, G Popradi, M Kaur, M Zhang, F Zhang, E Vandendries, K Asomaning, S Dorman, M Stelljes, DI Marks, A Cury, W Saber
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 45, Iss , Pp S256-S257 (2023)
Objectives: Inotuzumab ozogamicin (InO), a CD22-directed antibody-drug conjugate indicated for relapsed/refractory (R/R) B-cell precursor acute lymphoblastic leukemia (ALL), is associated with hepatotoxicity and hepatic veno-occlusive disease/sinusoi
Externí odkaz:
https://doaj.org/article/3cdf7c6e5423497684e702bceb898c51
Autor:
Henri C Chung, Christine L Foxx, Jessica A Hicks, Tod P Stuber, Iddo Friedberg, Karin S Dorman, Beth Harris
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0290473 (2023)
Understanding the microbial genomic contributors to antimicrobial resistance (AMR) is essential for early detection of emerging AMR infections, a pressing global health threat in human and veterinary medicine. Here we used whole genome sequencing and
Externí odkaz:
https://doaj.org/article/71ee651b5cac4fb987877fabb5e458d3
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 35, Iss 5, Pp 2102-2111 (2021)
Abstract Background Angiotensin‐converting enzyme inhibitors (ACEIs) are commonly prescribed in dogs, but the ideal dosage is unknown. Hypothesis/Objectives In dogs with cardiac disease, a dose‐response relationship exists for ACEIs with respect
Externí odkaz:
https://doaj.org/article/c20b802fee6649ea92ff3682c832b4c3
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 4, p e1008890 (2021)
Protein-protein interaction networks are one of the most effective representations of cellular behavior. In order to build these models, high-throughput techniques are required. Next-generation interaction screening (NGIS) protocols that combine yeas
Externí odkaz:
https://doaj.org/article/d5a3da1240484b5c812bf7444fedffcf
Autor:
Jacob S. Dorman
Publikováno v:
The Journal of African American History. 108:23-49
Autor:
Qingyun Li, Xiyu Peng, Eric R. Burrough, Orhan Sahin, Stacie A. Gould, Nicholas K. Gabler, Crystal L. Loving, Karin S. Dorman, John F. Patience
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Post-weaning diarrhea caused by enterotoxigenic E. coli (ETEC) causes significant economic losses for pig producers. This study was to test the hypotheses that an ETEC challenge disrupts intestinal microbial homeostasis and the inclusion of dietary s
Externí odkaz:
https://doaj.org/article/1acad60666c24dea835d34cebbb39e32
Autor:
Thomas Briese, Maria A. Loroño-Pino, Julian E. Garcia-Rejon, Jose A. Farfan-Ale, Carlos Machain-Williams, Karin S. Dorman, W. Ian Lipkin, Bradley J. Blitvich
Publikováno v:
Virology Journal, Vol 14, Iss 1, Pp 1-8 (2017)
Abstract Background We previously reported the discovery of a novel, putative flavivirus designated T’Ho virus in Culex quinquefasciatus mosquitoes in the Yucatan Peninsula of Mexico. A 1358-nt region of the NS5 gene was amplified and sequenced but
Externí odkaz:
https://doaj.org/article/e8fb48d26e8d45adb7840c3cd3cf2f42
Publikováno v:
Bioinformatics. 39
Motivation Allostery enables changes to the dynamic behavior of a protein at distant positions induced by binding. Here, we present APOP, a new allosteric pocket prediction method, which perturbs the pockets formed in the structure by stiffening pair