Zobrazeno 1 - 10
of 114
pro vyhledávání: '"S. Diane Hayward"'
Autor:
Angela Kwok Fung Lo, Kwok Wai Lo, Sai Wah Tsao, Hing Lok Wong, Jan Wai Ying Hui, Ka Fai To, S. Diane Hayward, Yiu Loon Chui, Yu Lung Lau, Kenzo Takada, Dolly P. Huang
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 3, Pp 173-180 (2006)
Epstein-Barr virus (EBV) latent infection is a critical event in nasopharyngeal carcinoma (NPC) tumorigenesis. EBV-encoded genes have been shown to be involved in immune evasion and in the regulation of various cellular signaling cascades. To elucida
Externí odkaz:
https://doaj.org/article/c7628f37866f492f8ce4e70e0eb23068
Autor:
Renfeng Li, Gangling Liao, Raja Sekhar Nirujogi, Sneha M Pinto, Patrick G Shaw, Tai-Chung Huang, Jun Wan, Jiang Qian, Harsha Gowda, Xinyan Wu, Dong-Wen Lv, Kun Zhang, Srikanth S Manda, Akhilesh Pandey, S Diane Hayward
Publikováno v:
PLoS Pathogens, Vol 11, Iss 12, p e1005346 (2015)
Epstein-Barr virus (EBV) is etiologically linked to infectious mononucleosis and several human cancers. EBV encodes a conserved protein kinase BGLF4 that plays a key role in the viral life cycle. To provide new insight into the host proteins regulate
Externí odkaz:
https://doaj.org/article/ac5147043afb46c6afa3b5f3411197f6
Autor:
Crystal L Woodard, C Rory Goodwin, Jun Wan, Shuli Xia, Robert Newman, Jianfei Hu, Jin Zhang, S Diane Hayward, Jiang Qian, John Laterra, Heng Zhu
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72671 (2013)
Protein phosphorylation is a dynamic and reversible event that greatly influences cellular function. Identifying the key regulatory elements that determine cellular phenotypes during development and oncogenesis requires the ability to dynamically mon
Externí odkaz:
https://doaj.org/article/638242fc6a6f4262a2da615d0a3467af
Kaposi's Sarcoma-Associated Herpesvirus LANA Modulates the Stability of the E3 Ubiquitin Ligase RLIM
Autor:
Hagar Tadmor, Meir Shamay, Gangling Liao, Anuj Ahuja, Melanie Greenway, Richard F. Ambinder, Ola Orgil, S. Diane Hayward
Publikováno v:
J Virol
The Kaposi’s sarcoma-associated herpesvirus (KSHV)-encoded latency-associated nuclear antigen (LANA) protein functions in latently infected cells as an essential participant in KSHV genome replication and as a driver of dysregulated cell growth. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::347202fbc1aab3a3571962625e3ef0ce
https://europepmc.org/articles/PMC7022369/
https://europepmc.org/articles/PMC7022369/
Autor:
Jennifer Stone, Richard F. Ambinder, S. Diane Hayward, Jae Myun Lee, Jun O. Liu, Jaeyeun Lee, John G. Kosowicz, Prashant Desai
Several therapeutic strategies targeting Epstein-Barr virus (EBV)-associated tumors involve upregulation of viral lytic gene expression. Evidence has been presented that the unfolded protein response (UPR) leads to EBV lytic gene expression. Clofocto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d97abe57057c6c1389d34077bd6ecca3
https://europepmc.org/articles/PMC6798122/
https://europepmc.org/articles/PMC6798122/
Autor:
Jun O. Liu, Curtis R. Chong, Hyunki Kim, Jeon Han Park, S. Diane Hayward, Richard F. Ambinder, Hyun Gyu Lee, Hyemi Kim, Jae Myun Lee, Pil Gu Park, Seung Myung Dong, Eun Jung Kim, Tae Hyun Choi, Jianmeng Chen
Publikováno v:
Oncotarget
The constant presence of the viral genome in Epstein-Barr virus (EBV)-associated gastric cancers (EBVaGCs) suggests the applicability of novel EBV-targeted therapies. The antiviral nucleoside drug, ganciclovir (GCV), is effective only in the context
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c110e895a2cde1817a884763c073239
https://doi.org/10.18632/oncotarget.5041
https://doi.org/10.18632/oncotarget.5041
Autor:
Jaeyeun Lee, Brandon J. Peiffer, Zufeng Guo, S. Diane Hayward, Gangling Liao, Jun O. Liu, Jianmeng Chen, John G. Kosowicz, Richard F. Ambinder
Publikováno v:
Journal of Virology. 91
Epstein-Barr virus (EBV) is a ubiquitous human gammaherpesvirus that establishes a latency reservoir in B cells. In this work, we show that ibrutinib, idelalisib, and dasatinib, drugs that block B cell receptor (BCR) signaling and are used in the tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f586b1bdf036b7fb7deb6b85747cc6
https://doi.org/10.1128/jvi.00747-17
https://doi.org/10.1128/jvi.00747-17
Autor:
Renfeng Li, S. Diane Hayward
Publikováno v:
Trends in Microbiology. 21:286-295
Herpesviruses are ubiquitous human pathogens that establish life-long persistent infections. Clinical manifestations range from mild self-limiting outbreaks such as childhood rashes and cold sores to the more severe and life threatening outcomes of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fbf3601745383448860cbe2ddf706e
https://doi.org/10.1016/j.tim.2013.03.005
https://doi.org/10.1016/j.tim.2013.03.005
Autor:
Leyao Wang, Renfeng Li, Catherine M. Guzzo, Michael J. Matunis, Gangling Liao, S. Diane Hayward, Heng Zhu
Publikováno v:
Journal of Virology. 86:5412-5421
An Epstein-Barr virus (EBV) protein microarray was used to screen for proteins binding noncovalently to the small ubiquitin-like modifier SUMO2. Among the 11 SUMO binding proteins identified was the conserved protein kinase BGLF4. The mutation of pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a2c5a1a108f140f1797b6e908b04c27
https://doi.org/10.1128/jvi.00314-12
https://doi.org/10.1128/jvi.00314-12
Autor:
Jun Wan, Otoniel Martinez-Maza, Jian Zhu, Jiang Qian, S. Diane Hayward, Leyao Wang, Dasheng Zheng, Crystal Woodard, Yong Gu Cho, Shweta G. Pai, Richard F. Ambinder, Heng Zhu, Chuang Jiun Chiou, Gangling Liao, Gary S. Hayward
Publikováno v:
The Journal of Infectious Diseases
Background. Epstein-Barr virus (EBV) is a ubiquitous herpesvirus, and Kaposi’s sarcoma–associated herpesvirus (KSHV) has a restricted seroprevalence. Both viruses are associated with malignancies that have an increased frequency in individuals wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6661bf22f1591f09da7b608ec8c452