Zobrazeno 1 - 3
of 3
pro vyhledávání: '"S. Denise Field"'
Autor:
Jason K. Dutra, Christopher W. am Ende, Finley Scott F. Serneo, Uthpala Seneviratne, Wankyu Lee, Douglas S. Johnson, Hua Xu, S. Denise Field, Jon Oyer
Publikováno v:
Chembiochem : a European journal of chemical biology. 21(20)
Novel chemical biology probes linking a serine hydrolase-directed fluorophosphonate warhead and cereblon-binding pomalidomide were assessed for the degradation of serine hydrolases. A quantitative proteomics approach to detect degraded proteins revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ab0b6a163ab659db704eb2a489f710
https://pubmed.ncbi.nlm.nih.gov/32501609
https://pubmed.ncbi.nlm.nih.gov/32501609
Autor:
Betty Pettersen, Lila Ramaiah, Nathanael G. Lintner, Kelly M. Knee, S. Denise Field, Reema Jasuja, Youngwook Ahn, Lindsay Tomlinson, Amey Barakat, Brendon Kapinos, Zane Wenzel
Publikováno v:
Blood. 136:27-28
Sickle cell disease (SCD) is a severe genetic disorder caused by a mutation in hemoglobin (b6Glu-Val), which allows the mutant hemoglobin to assemble into long polymers when deoxygenated. Over time, these polymers build up and deform red blood cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95d6b76f28888a18ef8f33b9c6205ac3
https://doi.org/10.1182/blood-2020-142052
https://doi.org/10.1182/blood-2020-142052
Publikováno v:
ACS chemical biology. 12(5)
PF-956980 has been used previously as a JAK3-selective chemical probe in numerous cell-based experiments. Here, we report that not only is PF-956980 a pan-JAK ATP-competitive inhibitor but it also causes selective reduction of endogenous JAK2 and JAK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00d304e139b53ae17977ff905096afd
https://pubmed.ncbi.nlm.nih.gov/28318222
https://pubmed.ncbi.nlm.nih.gov/28318222