Zobrazeno 1 - 10
of 94
pro vyhledávání: '"S. Dengler"'
Autor:
Joshua L. Smalley, Noell Cho, Shu Fun Josephine Ng, Catherine Choi, Abigail H. S. Lemons, Saad Chaudry, Christopher E. Bope, Jake S. Dengler, Chuansheng Zhang, Matthew N. Rasband, Paul A. Davies, Stephen J. Moss
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
The subunit composition of GABAA receptors and their interaction with beta spectrin complexes influences their localization between the neuronal axon initial segment or dendrites.
Externí odkaz:
https://doaj.org/article/edfc1bb22db642f7ab73e66911075353
Autor:
Catherine Choi, Joshua L. Smalley, Abigail H. S. Lemons, Qiu Ren, Christopher E. Bope, Jake S. Dengler, Paul A. Davies, Stephen J. Moss
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Impaired inhibitory signaling underlies the pathophysiology of many neuropsychiatric and neurodevelopmental disorders including autism spectrum disorders and epilepsy. Neuronal inhibition is regulated by synaptic and extrasynaptic γ-aminobutyric aci
Externí odkaz:
https://doaj.org/article/b30ccc0be6cc46cfb9340dd34a6deb46
Autor:
Jane R. Kenny, Mathew Williams, Richard Beasley, A. Mcgregor, Maria E. Wilson, Avi Eliahu, Irene Braithwaite, Matthew R. Durk, Jennifer Tom, Fang Cai, Ryan Owen, Joshua Galanter, Hart S. Dengler, Rui Zhu, Mark Zak, Hubert Chen
Publikováno v:
Journal of Allergy and Clinical Immunology. 148:783-789
Background The Janus kinase (JAK) pathway mediates the activity of many asthma-relevant cytokines, including IL-4 and IL-13. GDC-0214 is a potent, inhaled, small-molecule JAK inhibitor being developed for the treatment of asthma. Objective We sought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5929ba8f48ae2f44a826e35cc263796
https://doi.org/10.1016/j.jaci.2021.02.042
https://doi.org/10.1016/j.jaci.2021.02.042
Akademický článek
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Autor:
Joshua L, Smalley, Noell, Cho, Shu Fun Josephine, Ng, Catherine, Choi, Abigail H S, Lemons, Saad, Chaudry, Christopher E, Bope, Jake S, Dengler, Chuansheng, Zhang, Matthew N, Rasband, Paul A, Davies, Stephen J, Moss
Publikováno v:
Communications biology. 6(1)
Fast synaptic inhibition is dependent on targeting specific GABA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d826b5d44f667a3a41e47aa613ef778
https://pubmed.ncbi.nlm.nih.gov/36604600
https://pubmed.ncbi.nlm.nih.gov/36604600
Autor:
Sarah E. Headland, Hart S. Dengler, Daqi Xu, Grace Teng, Christine Everett, Rojo A. Ratsimandresy, Donghong Yan, Jing Kang, Kirthana Ganeshan, Evgeniya V. Nazarova, Sarah Gierke, Christopher J. Wedeles, Riccardo Guidi, Daryle J. DePianto, Katrina B. Morshead, Alison Huynh, Jessica Mills, Sean Flanagan, Shannon Hambro, Victor Nunez, Joanna E. Klementowicz, Yongchang Shi, Jianyong Wang, Jack Bevers, Vladimir Ramirez-Carrozzi, Rajita Pappu, Alex Abbas, Jason Vander Heiden, David F. Choy, Rajbharan Yadav, Zora Modrusan, Reynold A. Panettieri, Cynthia Koziol-White, William F. Jester, Brendan J. Jenkins, Yi Cao, Christine Clarke, Cary Austin, Daniel Lafkas, Min Xu, Paul J. Wolters, Joseph R. Arron, Nathaniel R. West, Mark S. Wilson
Publikováno v:
Science translational medicine. 14(627)
Exacerbations of symptoms represent an unmet need for people with asthma. Bacterial dysbiosis and opportunistic bacterial infections have been observed in, and may contribute to, more severe asthma. However, the molecular mechanisms driving these exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46323ac4e1c7c49de3c9a3a4fd365072
https://pubmed.ncbi.nlm.nih.gov/35110748
https://pubmed.ncbi.nlm.nih.gov/35110748
Autor:
M. Emberger, Marion Wobser, Doris Helbig, Carmen Loquai, Oana-Diana Persa, Alexander Kreuter, Cornelia Mauch, A. Volz, S. Dengler, M. Baltaci, M. Doerler, Martin Laimer
Publikováno v:
Journal of the European Academy of Dermatology and Venereology. 33:1577-1580
BACKGROUND Pleomorphic dermal sarcomas (PDS) are frequent UV-induced sarcomas of the skin of intermediate grade malignant potential. Despite the fact that PDS have a noteworthy potential to recur (up to 28%) as well as to metastasize (up to 20%), the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8383794ef8c0cb4832f0e122a0fc02b
https://doi.org/10.1111/jdv.15493
https://doi.org/10.1111/jdv.15493
Publikováno v:
Optical Fiber Sensors Conference 2020 Special Edition.
Results from field measurement campaigns for structural health monitoring (SHM) at giant mine heaps by optical time domain reflectometry (OTDR) in polymer optical fibers (POF) are presented. Polymer geogrids built for soil reinforcement are fitted wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81c1da6afe3d03bc4b4ca3fd8de467b5
https://doi.org/10.1364/ofs.2020.th4.7
https://doi.org/10.1364/ofs.2020.th4.7
Publikováno v:
SMSI 2021 - Sensors and Instrumentation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29b7bb448400d4aeee75f3861c5d6854
https://doi.org/10.5162/smsi2021/b8.3
https://doi.org/10.5162/smsi2021/b8.3
Autor:
Jonathan M. Maher, Rui Zhang, Gopinath Palanisamy, Kimberly Perkins, Lynda Liu, Patrick Brassil, Alexander McNamara, Arthur Lo, Adam D. Hughes, Jitendra Kanodia, Svitlana Kulyk, Kristen J. Nikula, Hart S. Dengler, Amy Scandurra, Ingrid Lua, Eric Harstad
Publikováno v:
Toxicology and Applied Pharmacology. 438:115905
Systemic therapies targeting transforming growth factor beta (TGFβ) or TGFβR1 kinase (ALK5) have been plagued by toxicities including cardiac valvulopathy and bone physeal dysplasia in animals, posing a significant challenge for clinical developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4606385857511b66512fdf43a79a65bf
https://doi.org/10.1016/j.taap.2022.115905
https://doi.org/10.1016/j.taap.2022.115905