Zobrazeno 1 - 10
of 405
pro vyhledávání: '"S. Degani"'
Autor:
Mahin K. Ibrahim, Shivani R. Nandha, Ashwani S. Patil, Sadhana Sathaye, Mariam S. Degani, Binita Kumar, Rahul Checker, Deepak Sharma, Santosh K. Sandur
Publikováno v:
Advances in Redox Research, Vol 8, Iss , Pp 100071- (2023)
Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene;PTS), a dimethyl ether analogue of resveratrol, has been shown to possess anti-bacterial, anti-cancer, anti-inflammatory and antioxidant properties. In the present study, we have synthesized a mito
Externí odkaz:
https://doaj.org/article/17c2fd29f0424dfea1261070eae3251c
Autor:
Ashwani S. Patil, Mahin K. Ibrahim, Sadhana Sathaye, Mariam S. Degani, Debojyoti Pal, Rahul Checker, Deepak Sharma, Santosh K. Sandur
Publikováno v:
Applied Biochemistry and Biotechnology. 195:2057-2076
Publikováno v:
International Journal of Mycobacteriology, Vol 4, Iss 2, Pp 97-103 (2015)
Background: Dihydrofolate reductase (DHFR) (dfrA gene) is an essential enzyme for cell survival and an unexplored target in Mycobacterium tuberculosis (Mtb). This study was carried out to analyze mutations in the dfrA gene amongst 20 clinical DNA sam
Externí odkaz:
https://doaj.org/article/141ecba4565f4f098cbf1bed2d43870a
Autor:
Mariam S. Degani, Swati Vyas, Mihir Khambete, Ronak B. Gudhka, Shail Panchamia, Vandana B. Patravale
Publikováno v:
Drug Delivery and Translational Research. 10:1085-1094
Controlling structurally defined properties of drug-bound macromolecules such as surface adhesion and interaction with endogenous proteins in the surrounding environment using prior data from computer-assisted simulation can be of great use in design
Autor:
Ronak B. Gudhka, Mariam S. Degani, Vandana B. Patravale, Shail Panchamia, Mihir Khambete, Swati Vyas
Publikováno v:
Drug Delivery and Translational Research. 10:1076-1084
Indigenous polymers have functional implications in biomedicine due to the presence of an inherent favorable structural architecture that supports hydrogel formation. In this study, we present the molecular level characterization of xyloglucan hydrog
Microwave-assisted ligand-free, base-free Heck reactions in a task-specific imidazolium ionic liquid
Autor:
Mahesh G. Dighe, Mariam S. Degani
Publikováno v:
ARKIVOC, Vol 2011, Iss 11, Pp 189-197 (2011)
Externí odkaz:
https://doaj.org/article/097545dcb07c4ee295b3e7fe9d74e0d4
Autor:
Arundhati Maitra, Tulika Munshi, Mihir Khambete, Antima Gupta, Sanjib Bhakta, Mariam S. Degani, Neha Agre
Publikováno v:
Chemical Biology & Drug Design. 95:192-199
We report the biological evaluation of 5-(5-nitrothiophen-2-yl)-4,5-dihydro-1H-pyrazole derivatives against bacteria, eukaryotic cell lines and the assessment of their mechanisms of action to determine their prospects of being developed into potent a
Autor:
Amit Mirani, Vandana B. Patravale, Vainav Patel, Harish Kundaikar, Shilpa M. Velhal, Atmaram H. Bandivdekar, Mariam S. Degani
Publikováno v:
Current HIV Research. 17:102-113
Background:Lack of effective early-stage HIV-1 inhibitor instigated the need for screening of novel gp120-CD4 binding inhibitor. Polyphenols, a secondary metabolite derived from natural sources are reported to have broad spectrum HIV-1 inhibitory act
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:1999-2007
With the increasing number of cases of latent and drug resistant tuberculosis, there is an urgent need to develop new, potent molecules capable of combating this deadly disease. Molecules containing oxadiazoles are one such class that could be consid
Autor:
Mariam S. Degani, Bandoo C. Chatale
Publikováno v:
Drug Development and Industrial Pharmacy. 45:1590-1598
Meloxicam (MX), a nonsteroidal anti-inflammatory drug, widely used to treat arthritis, has a very bitter taste. Chemical modification of the bitter functionality was achieved by synthesis of a prodrug, meloxicam pivalate (MXP). Taste improvement was