Zobrazeno 1 - 10 of 42 pro vyhledávání: '"S. D. Yuzhakov"'
1
Experience in creating new drugs using traditional technologies
Autor: S. D. Yuzhakov, R. G. Glushkov
Publikováno v: Pharmaceutical Chemistry Journal. 45:517-521
Working hypotheses for the creation of new potential drugs including Class III antiarrhythmic (nibentan, niferidyl), antiallergic (theoritin), and antituberculosis (hixozid) agents are formulated and experimental data on the activity of the obtained
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::982de0c3d96955745c5c77d8297dd3b5
https://doi.org/10.1007/s11094-011-0670-3
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2
New group of class III antiarrhythmic drugs: piperid-4-ylethane derivatives
Autor: E. N. Salin, N. K. Davydova, Glushkov Robert G, A. I. L'vov, V. V. Asnina, O. S. Sizova, S. D. Yuzhakov, G. P. Zhikhareva
Publikováno v: Pharmaceutical Chemistry Journal. 45:65-74
A series of new piperid-4-ylethane derivatives possessing antiarrhythmic activity has been synthesized and studied. The most active compound, 1-(4-fluorophenyl)-1-(4-nitrobenzoylamino)-2-(N-ethylpiperid-4-yl)ethane (niferidyl) hydrochloride, was sele
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f11912d1462334fbd68bb605fc69d6ea
https://doi.org/10.1007/s11094-011-0562-6
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3
Combined Action of the Anticholinesterase Drug Aminostigmine and the Antidepressant Pyrazidole on Mnemonic Function in Rats and Mice
Autor: Glushkov Robert G, S. D. Yuzhakov, V. A. Parshin, N. I. Andreeva, V. V. Asnina, M. A. Kalinkina
Publikováno v: Pharmaceutical Chemistry Journal. 39:4-7
The effect of aminostigmine alone and in combination with pyrazidole on mnemonic function in rats and mice was studied using passive avoidance conditioned reflex. Aminostigmine is comparable with the reference drug galanthamine in the ability to impr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0fb54556265ed865d3d5b595c5472843
https://doi.org/10.1007/s11094-005-0067-2
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6
Synthesis and pharmacological study of 5-phenoxymethyl-1,2,4-oxadiazole derivatives
Autor: S. D. Sokolov, O. S. Anisimova, O. G. Azarevich, S. D. Yuzhakov, M. V. Berg, K. F. Turchin, M. D. Mashkovskii, S. M. Vinogradova
Publikováno v: Pharmaceutical Chemistry Journal. 29:119-123
Novel 3-amino-2-hydroxypropoxy derivatives of 5-phenoxymethyl-1,2,4-oxadiazole were synthesized. Compounds were discovered among them that had pronounced Β-adrenergic blocking activity combined with moderate α-adrenergic blocking properties.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74be612d822d98b63a5ff16842f25c6d
https://doi.org/10.1007/bf02226523
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8
A potential combined formulation containing vinpocetin and succinic acid
Autor: Glushkov Robert G, E. N. Salin, V. V. Asnina, M. V. Alekseev, S. D. Yuzhakov, N. I. Andreeva
Publikováno v: Pharmaceutical Chemistry Journal. 45
Succinic acid bas been found to be able to potentiate the antihypoxic activity of vinpocetin. This property (potentiation) provided grounds for creating a new combined formulation containing vinpocetin and succinic acid, which has more marked antihyp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d447445a360e4e7af61cd028af1c80c
https://doi.org/10.1007/s11094-011-0594-y
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9
New potential antihypoxants based on 2-ethyl-3-(N,N-dimethylcarbamoyloxy)-6-methylpyridine
Autor: E. N. Salin, V. V. Asnina, M. V. Alekseev, S. D. Yuzhakov, L. N. Dronova, Glushkov Robert G, N. I. Andreeva
Publikováno v: Pharmaceutical Chemistry Journal. 45
It is established that succinic acid is capable of potentiating (synergism) the antihypoxic activity of 3-hydroxypyridine derivatives such as the succinate (Ia) and hydrochloride (Ib) of 3-(N,N-dimethylcarbamoyloxy)- 2-ethyl-6-methylpyridine. This ef
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::30f7b0f7dfbb5bf3f35aef3b3c095fe5
https://doi.org/10.1007/s11094-011-0575-1
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10
A new group of 1-and 7-[ω-(benzhydryl-1-alkyl]-3methylxanthine derivatives with antihistamine activity
Autor: S. D. Yuzhakov, E. N. Salin, N. I. Andreeva, N. M. Sazonova, V. V. Asnina, V. A. Shorr, G. F. Zhdanov, M. V. Alekseev, E. M. Dolginova, Glushkov Robert G, O. S. Fominova
Publikováno v: Pharmaceutical Chemistry Journal. 45
Directed synthesis using the accessible compound 3-methylxanthine was used to obtain a new group of 1-and 7-[ω-(benzhydryl-1)alkyl]-3-methylxanthine derivatives which functioned as histamine receptor blockers. The compound which was most active, had
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::823f8dc0fb69e7455b2217c5780a71cd
https://doi.org/10.1007/s11094-011-0549-3
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