Zobrazeno 1 - 6
of 6
pro vyhledávání: '"S. D. Yogesha"'
Autor:
Hari Priya Parameshwaran, S. D. Yogesha, Mark Walter Keilbarth, Ramya Sundaresan, Rakhi Rajan
Publikováno v:
Cell Reports, Vol 21, Iss 13, Pp 3728-3739 (2017)
Cell reports
Cell reports
SUMMARY CRISPR-Cas systems provide bacteria and archaea with sequence-specific protection against invading mobile genetic elements. In the presence of divalent metal ions, Cas9 and Cas12a (formerly Cpf1) proteins target and cleave DNA that is complem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6235ec23951d8719b94d303a82621333
http://www.sciencedirect.com/science/article/pii/S2211124717317849
http://www.sciencedirect.com/science/article/pii/S2211124717317849
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10679 (2010)
Cells require distinct adhesion complexes to form contacts with their neighbors or the extracellular matrix, and vinculin links these complexes to the actin cytoskeleton. Metavinculin, an isoform of vinculin that harbors a unique 68-residue insert in
Externí odkaz:
https://doaj.org/article/bd340fb1d5cb44cfb775fac040e05609
Autor:
Peter Z. Qin, Wei Jiang, S. D. Yogesha, Richard H. Nguyen, Nadia Amrani, Rakhi Rajan, Kesavan Babu
Publikováno v:
Biochemistry. 58(14)
CRISPR-Cas systems are RNA-guided nucleases that provide adaptive immune protection for bacteria and archaea against intruding genomic materials. The programmable nature of CRISPR-targeting mechanisms has enabled their adaptation as powerful genome e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d846fd7ac672f03e65776cbeb2a85dad
https://pubmed.ncbi.nlm.nih.gov/30916546
https://pubmed.ncbi.nlm.nih.gov/30916546
Nucleic Acid-Dependent Conformational Changes in CRISPR–Cas9 Revealed by Site-Directed Spin Labeling
Autor:
Rakhi Rajan, Peter Z. Qin, Richard H. Nguyen, Xiaojun Zhang, S. D. Yogesha, Carolina Reyes, Narin S. Tangprasertchai
Publikováno v:
Cell Biochemistry and Biophysics. 75:203-210
In a type II clustered regularly interspaced short palindromic repeats (CRISPR) system, RNAs that are encoded at the CRISPR locus complex with the CRISPR-associated (Cas) protein Cas9 to form an RNA-guided nuclease that cleaves double-stranded DNAs a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb3a2c70acfa71b93995068d415ea9f0
https://doi.org/10.1007/s12013-016-0738-5
https://doi.org/10.1007/s12013-016-0738-5
Publikováno v:
Protein science : a publication of the Protein Society. 21(4)
The cytoskeletal protein talin activates integrin receptors by binding of its FERM domain to the cytoplasmic tail of β-integrin. Talin also couples integrins to the actin cytoskeleton, largely by binding to and activating the cytoskeletal protein vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4bd7ee30c72624d00ac67f70bf59c60c
https://pubmed.ncbi.nlm.nih.gov/22334306
https://pubmed.ncbi.nlm.nih.gov/22334306
Publikováno v:
Protein science : a publication of the Protein Society. 20(8)
The cytoskeletal proteins talin and vinculin are localized at cell-matrix junctions and are key regulators of cell signaling, adhesion, and migration. Talin couples integrins via its FERM domain to F-actin and is an important regulator of integrin ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50faa8e4c724234d6b7dea12d009baef
https://pubmed.ncbi.nlm.nih.gov/21648001
https://pubmed.ncbi.nlm.nih.gov/21648001