Zobrazeno 1 - 3
of 3
pro vyhledávání: '"S. D. Van Haren"'
Autor:
Ruth A. Ettinger, Jan Voorberg, S. D. Van Haren, Kathleen P. Pratt, Eddie A. James, Karin Fijnvandraat, William W. Kwok, Joseph A. Liberman
Publikováno v:
Journal of thrombosis and haemostasis, 9(4), 689-699. Wiley-Blackwell
Summary. Background: Development of neutralizing anti-factor (F)VIII antibodies (‘inhibitors’) is a serious clinical problem in hemophilia A. Increased inhibitor risk has been associated with certain FVIII missense substitutions, including R593C
Autor:
S. D. Van Haren, Jan Voorberg, P. M. W. Van Helden, H. Marijke van den Berg, Karin Fijnvandraat
Publikováno v:
Haemophilia. 16:35-43
Summary. Development of inhibitory antibodies to factor VIII (FVIII) provides a major complication of replacement therapy in patients with haemophilia A. The risk of inhibitor formation is influenced by the underlying FVIII gene defect. Moreover, gen
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 16(102)
Development of inhibitory antibodies to factor VIII (FVIII) provides a major complication of replacement therapy in patients with haemophilia A. The risk of inhibitor formation is influenced by the underlying FVIII gene defect. Moreover, genetic dete