Výsledky vyhledávání - "S. D. Isaacs"

Role of NF?B in the regulation of macrophage colony stimulating factor by tumor necrosis factor-? in ST2 bone stromal cells

Autor: H. Gewant, Mark S. Nanes, D. Fan, S. D. Isaacs, Paul Farmer, Tamara C. Murphy, W. R. Taylor, Xian Fan, Janet Rubin

Publikováno v: Journal of Cellular Physiology. 179:193-200

Expression of MCSF in bone is important to the regulation of osteoclastogenesis. We show here that tumor necrosis factor-alpha (TNFalpha) increases the production of both soluble (sMCSF) and membrane-bound (mMCSF) macrophage colony stimulating factor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ebb674b91fc462e634398732d78fd1f
https://doi.org/10.1002/(sici)1097-4652(199905)179:2<193::aid-jcp9>3.0.co

Zobrazit plný text záznamu

Linkage and association of CYP17 gene in hereditary and sporadic prostate cancer

Autor: B, Chang, S L, Zheng, S D, Isaacs, K E, Wiley, J D, Carpten, G A, Hawkins, E R, Bleecker, P C, Walsh, J M, Trent, D A, Meyers, W B, Isaacs, J, Xu

Publikováno v: International journal of cancer. 95(6)

Androgens are essential for prostate development, growth and maintenance and the association between androgen levels and prostate cancer is well established. Since the CYP17 gene encodes the enzyme cytochrome P450c17alpha, which mediates 17alpha-hydr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ca31bde120e09387245464ea31670bb7
https://pubmed.ncbi.nlm.nih.gov/11668516

Zobrazit plný text záznamu

No evidence for a role of BRCA1 or BRCA2 mutations in Ashkenazi Jewish families with hereditary prostate cancer

Autor: E P, Wilkens, D, Freije, J, Xu, D R, Nusskern, H, Suzuki, S D, Isaacs, K, Wiley, P, Bujnovsky, D A, Meyers, P C, Walsh, W B, Isaacs

Publikováno v: The Prostate. 39(4)

Two genes responsible for hereditary breast cancer (BRCA1 and BRCA2) have been identified, and predisposing mutations identified. Several studies have provided evidence that germline mutations in BRCA1 and BRCA2 confer an increased risk of prostate c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5897e30972eb7eae3670e155ef0093f1
https://pubmed.ncbi.nlm.nih.gov/10344217

Zobrazit plný text záznamu

Role of NFkappaB in the regulation of macrophage colony stimulating factor by tumor necrosis factor-alpha in ST2 bone stromal cells

Autor: S D, Isaacs, X, Fan, D, Fan, H, Gewant, T C, Murphy, P, Farmer, W R, Taylor, M S, Nanes, J, Rubin

Publikováno v: Journal of cellular physiology. 179(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dafe2dd6d047c15e207b29abd062a1dd
https://pubmed.ncbi.nlm.nih.gov/10199558

Zobrazit plný text záznamu

Vitamin D receptor polymorphisms and lethal prostate cancer

Autor: A S, Kibel, S D, Isaacs, W B, Isaacs, G S, Bova

Publikováno v: The Journal of urology. 160(4)

Reports in the osteoporosis literature demonstrating the increased activity of specific alleles of the vitamin D receptor and epidemiological data linking vitamin D levels with prostate cancer have stimulated research into possible associations betwe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::74752a2beec3ba8f3ad2ef038758cdb0
https://pubmed.ncbi.nlm.nih.gov/9751364

Zobrazit plný text záznamu

Biological aggressiveness of hereditary prostate cancer: long-term evaluation following radical prostatectomy

Autor: G S, Bova, A W, Partin, S D, Isaacs, B S, Carter, T L, Beaty, W B, Isaacs, P C, Walsh

Publikováno v: The Journal of urology. 160(3 Pt 1)

We answer the question of whether, following radical prostatectomy, prostate cancer in patients with a family history of prostate cancer relapses biochemically at the same rate as prostate cancer in appropriately matched patients with no family histo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c4975b9695471cd5d483a1ef74178bd6
https://pubmed.ncbi.nlm.nih.gov/10210420

Zobrazit plný text záznamu

Early age at diagnosis in families providing evidence of linkage to the hereditary prostate cancer locus (HPC1) on chromosome 1

Autor: H, Grönberg, J, Xu, J R, Smith, J D, Carpten, S D, Isaacs, D, Freije, G S, Bova, J E, Danber, A, Bergh, P C, Walsh, F S, Collins, J M, Trent, D A, Meyers, W B, Isaacs

Publikováno v: Cancer research. 57(21)

In a recent study of 91 families having at least three first degree relatives with prostate cancer, we reported the localization of a major susceptibility locus for prostate cancer (HPC1) to chromosome 1 [band q24; J. R. Smith et al., Science (Washin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::105353d16a99d00ba47bb459ea45d7e4
https://pubmed.ncbi.nlm.nih.gov/9354426

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání