Zobrazeno 1 - 10 of 45 pro vyhledávání: '"S. D. Baker"'
1
The Effects of Pazopanib on Doxorubicin Pharmacokinetics in Children and Adults with Non-Rhabdomyosarcoma Soft Tissue Sarcoma: A Report from Children’s Oncology Group and NRG Oncology Study ARST1321
Autor: J. Gartrell, J. C. Panetta, S. D. Baker, Y. L. Chen, D. S. Hawkins, A. Ostrenga, T. J. Scharschmidt, S. L. Spunt, D. Wang, A. R. Weiss
Publikováno v: Cancer Chemother Pharmacol
PURPOSE: The use of tyrosine kinase inhibitors for the treatment for soft tissue sarcomas is increasing given promising signals of activity in a variety of tumor types. The recently completed study in non-rhabdomyosarcoma soft tissue sarcomas, ARST13
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4976171463bb4c468c53b7a3897a687
https://europepmc.org/articles/PMC8958317/
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2
An evaluation of the effects of persistent environmental contaminants on the reproductive success of Great Blue Herons (Ardea herodias) in Indiana
Autor: S. D. Baker, Maria S. Sepúlveda
Publikováno v: Ecotoxicology. 18:271-280
Contaminants in Great Blue Herons (Ardea herodias) from Indiana were quantified to determine if levels were high enough to impair reproduction. During 2005 and 2006, 35 eggs were collected from 6 colonies and analyzed for contaminants. Between 30 and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1b7eeaa5ddd6381c55f22f21423df0
https://doi.org/10.1007/s10646-008-0281-2
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4
Residual feed intake of purebred Angus steers: Effects on meat quality and palatability
Autor: T. A. Klein, Rodney A. Hill, R. A. Battaglia, D. G. Falk, S. D. Baker, J. C. Miller, J.B. Glaze, J. I. Szasz, P. S. Kuber, R. Richard, Carl W. Hunt
Publikováno v: Journal of Animal Science. 84:938-945
Relationships between residual feed intake (RFI) and other performance variables were determined using 54 purebred Angus steers. Individual feed intake and BW gain were recorded during a 70-d post-weaning period to calculate RFI. After the 70-d post-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6379631e7b9d63a78f4113ac12286c
https://doi.org/10.2527/2006.844938x
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6
Tumor targeting by covalent conjugation of a natural fatty acid to paclitaxel
Autor: M O, Bradley, N L, Webb, F H, Anthony, P, Devanesan, P A, Witman, S, Hemamalini, M C, Chander, S D, Baker, L, He, S B, Horwitz, C S, Swindell
Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 7(10)
Certain natural fatty acids are taken up avidly by tumors for use as biochemical precursors and energy sources. We tested in mice the hypothesis that the conjugation of docosahexaenoic acid (DHA), a natural fatty acid, and an anticancer drug would cr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::555f9c998945b789db175f7735df72c6
https://pubmed.ncbi.nlm.nih.gov/11595719
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8
A phase I dose escalation and bioavailability study of oral sodium phenylbutyrate in patients with refractory solid tumor malignancies
Autor: J, Gilbert, S D, Baker, M K, Bowling, L, Grochow, W D, Figg, Y, Zabelina, R C, Donehower, M A, Carducci
Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 7(8)
Phenylbutyrate (PB) is an aromatic fatty acid with multiple mechanisms of action including histone deacetylase inhibition. Preclinically, PB demonstrates both cytotoxic and differentiating effects at a concentration of 0.5 mM. We conducted a Phase I
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f73324d963d70cf97fa06d247ebf6987
https://pubmed.ncbi.nlm.nih.gov/11489804
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9
Oral paclitaxel and concurrent cyclosporin A: targeting clinically relevant systemic exposure to paclitaxel
Autor: C D, Britten, S D, Baker, L J, Denis, T, Johnson, R, Drengler, L L, Siu, K, Duchin, J, Kuhn, E K, Rowinsky
Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 6(9)
Oral paclitaxel is not inherently bioavailable because of the overexpression of P-glycoprotein by intestinal cells and the significant first-pass extraction by cytochrome P450-dependent processes. This study sought to simulate the toxicological and p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6d602bf1333095e5acdaf81b40752cf1
https://pubmed.ncbi.nlm.nih.gov/10999729
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10
A phase I and pharmacokinetic study of the mitochondrial-specific rhodacyanine dye analog MKT 077
Autor: C D, Britten, E K, Rowinsky, S D, Baker, G R, Weiss, L, Smith, J, Stephenson, M, Rothenberg, L, Smetzer, J, Cramer, W, Collins, D D, Von Hoff, S G, Eckhardt
Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 6(1)
This Phase I study was performed to evaluate the tolerability and pharmacokinetic behavior of MKT-077, a water soluble rhodacyanine dye analogue, which partitions into tumor cell mitochondria where it is thought to act as a metabolic poison, leading
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9658be56959ab053787d98fb6683c930
https://pubmed.ncbi.nlm.nih.gov/10656430
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