Zobrazeno 1 - 10
of 36
pro vyhledávání: '"S. Clements-Jewery"'
Publikováno v:
Journal of leukocyte biology. 47(2)
Recombinant human Interleukin-1 (rhlL-1) β was found to enhance stimulus-induced granule exocytosis from human polymorphonuclear leukocytes (PMNs). PMNs were incubated with rhlL-1β and then stimulated with either heat-aggregated IgG (Hagg) or N-for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0be904cbe05974d2c0ccd2ae3bada2
https://pubmed.ncbi.nlm.nih.gov/2154524
https://pubmed.ncbi.nlm.nih.gov/2154524
Publikováno v:
Neuropharmacology. 21:197-200
Some pharmacological actions of (±) — cis — and (±) — trans -2-(aminomethyl) cyclopropane carboxylic acids, conformationally restricted analogues of GABA, are described. The trans isomer (TAMP) was 17 and 4.5 times less active than GABA in hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8d31fc59a8e94640870d0dadc347fb
https://doi.org/10.1016/0028-3908(82)90163-0
https://doi.org/10.1016/0028-3908(82)90163-0
Autor:
S. Clements-Jewery, P.A. Robson
Publikováno v:
Neuropharmacology. 19:657-661
The in vitro and in vivo occupation of [ 3 H]-spiperone binding sites in, respectively, rat and mouse frontal cortex and striatum by several putative 5-hydroxytryptamine (5-HT) antagonists and members of other psychotropic drug classes has been asses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ae86182438ad2dc5b648e468649d3a
https://doi.org/10.1016/0028-3908(80)90040-4
https://doi.org/10.1016/0028-3908(80)90040-4
Autor:
P.A. Robson, S. Clements-Jewery
Publikováno v:
Neuropharmacology. 21:725-727
Chronic treatment of rats with the antidepressant, amitriptyline, resulted in a reduced number of cerebral cortical 5HT2 receptors measured as cinanserin displaceable [3H] spiperone binding. Pretreatment of rats with the serotonergic neurotoxin, p-ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324b1f0db2596926bf21647192f0b499
https://doi.org/10.1016/0028-3908(82)90018-1
https://doi.org/10.1016/0028-3908(82)90018-1
Autor:
S, Clements-Jewery, P A, Robson
Publikováno v:
Neuropharmacology. 20(12B)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39bdea3344a1035917187256699e00ce
https://pubmed.ncbi.nlm.nih.gov/7322304
https://pubmed.ncbi.nlm.nih.gov/7322304
Autor:
S. Clements-Jewery
Publikováno v:
Antimicrobial agents and chemotherapy. 9(4)
A potential bioassay method for nystatin has been developed based on the ability of this antibiotic to bring out dose-related potassium ion efflux from susceptible cells of Saccharomyces cerevisiae , such extracellular potassium ion concentration bei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963fa7f078999184798d929cbaf0e9ee
https://pubmed.ncbi.nlm.nih.gov/773299
https://pubmed.ncbi.nlm.nih.gov/773299
Autor:
S. Clements-Jewery, R. Murdoch, W. R. Tully, Saroop S. Matharu, Robert Westwood, G. W. Danswan, Colin R. Gardner
Publikováno v:
ChemInform. 19
Several series of heterocyclic carboxylic esters were found to be active in the benzodiazepine receptor binding assay, a typical example being ethyl 7-ethyl-5-methoxyimidazo[1,2-a]quinoline-2-carboxylate (4b) with an IC50 of 150 nM. The corresponding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd60ca0e214739f551f83f532a74466d
https://doi.org/10.1002/chin.198843201
https://doi.org/10.1002/chin.198843201
Autor:
G. W. Danswan, Saroop S. Matharu, S. Clements-Jewery, W. R. Tully, Colin R. Gardner, R. Murdoch, Robert Westwood
Publikováno v:
Journal of medicinal chemistry. 31(6)
Several series of heterocyclic carboxylic esters were found to be active in the benzodiazepine receptor binding assay, a typical example being ethyl 7-ethyl-5-methoxyimidazo[1,2-a]quinoline-2-carboxylate (4b) with an IC50 of 150 nM. The corresponding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24cfb6e6a55120681600262bae2121ad
https://pubmed.ncbi.nlm.nih.gov/2897468
https://pubmed.ncbi.nlm.nih.gov/2897468
Autor:
S. Clements-Jewery
Publikováno v:
Neuropharmacology. 17(9)
Chronic, but not acute, treatment of rats with 10mg/kg/day Trazodone, Doxepin and Mianserine decreased the specific binding of [3H] dihydroalprenolol, a potent β-adrenergic antagonist, to cortical membrane preparations, to respectively 21, 65 and 82
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21431d1adb37fc89b20dc75e92adb76
https://pubmed.ncbi.nlm.nih.gov/211460
https://pubmed.ncbi.nlm.nih.gov/211460
Autor:
P.F. Hunt, S. Clements-Jewery
Publikováno v:
Neuropharmacology. 20(4)
A novel steroid derivative, R 5135 (3α-hydroxy-16-imino-5β-17-aza-androstan-11-one) showed high affinity for both the GABA and glycine receptors in vitro. It also displaced [3H]diazepam from the benzodiazepine receptor in a rat cortex membrane prep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5116db9fbd8a36be1acbcb1916da9e77
https://pubmed.ncbi.nlm.nih.gov/6270588
https://pubmed.ncbi.nlm.nih.gov/6270588