Zobrazeno 1 - 5
of 5
pro vyhledávání: '"S. Christopher Davis"'
Publikováno v:
Journal of Statistical Planning and Inference. 139:2498-2501
In response surface methodology, one is usually interested in estimating the optimal conditions based on a small number of experimental runs which are designed to optimally sample the experimental space. Typically, regression models are constructed f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98ef166ab62d633cfec9a6987f9454ac
https://doi.org/10.1016/j.jspi.2008.10.002
https://doi.org/10.1016/j.jspi.2008.10.002
Autor:
Roger A. Sheldon, Lisa M. Newman, Emily Mundorff, Richard J. Fox, John C Whitman, Gjalt W. Huisman, Loleta M Chung, Steven K. Ma, S. Christopher Davis, Charlene Ching, John M. Gruber, Vesna Gavrilovic, John H. Grate, Sheela Muley, Sarena Tam
Publikováno v:
Nature Biotechnology. 25:338-344
We describe a directed evolution approach that should find broad application in generating enzymes that meet predefined process-design criteria. It augments recombination-based directed evolution by incorporating a strategy for statistical analysis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4402e955f779b04c3061c8cc90a7d03
https://doi.org/10.1038/nbt1286
https://doi.org/10.1038/nbt1286
Autor:
S. Christopher Davis, Gillian Edwards, Peter M. Zygmunt, Edward D. Högestätt, Arthur H. Weston
Publikováno v:
British Journal of Pharmacology. 118:1147-1152
1. The possibility that the endothelium-derived hyperpolarising factor (EDHF) in the rat hepatic artery is a cytochrome P450 mono-oxygenase metabolite of arachidonic acid was examined in the present study. In this preparation, acetylcholine elicits E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fdb31ef9112b66f37c0bb058b9f14c6
https://doi.org/10.1111/j.1476-5381.1996.tb15517.x
https://doi.org/10.1111/j.1476-5381.1996.tb15517.x
Publikováno v:
Archives of biochemistry and biophysics. 328(1)
Cytochrome P450 enzymes oxidize aldehydes either to the corresponding acid or, via a decarboxylation mechanism, to an olefin one carbon shorter than the parent substrate. To explore the factors that control partitioning between these two pathways, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::182b30ab0fb3504b3a6e8e0f2afbdc09
https://pubmed.ncbi.nlm.nih.gov/8638935
https://pubmed.ncbi.nlm.nih.gov/8638935
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