Zobrazeno 1 - 10
of 17
pro vyhledávání: '"S. Christian Cheatham"'
Autor:
Eun Kyoung Chung, S. Christian Cheatham, Daniel P. Healy, Andrea H. Stock, Sara Utley, Maureen Campion, Timothy Murrey, Alicia M. Gesenhues, Julia Jeffery, Michael B. Kays
Publikováno v:
International Journal of Antimicrobial Agents. 61:106751
Autor:
Kyeoul Jeong, Eun Kyoung Chung, S Christian Cheatham, Andrea H Stock, Sara Utley, Daniel P Healy, Maureen G Campion, Timothy Murrey, Alicia M Gesenhues, Julia Jeffery, Michael B Kays
Publikováno v:
Open Forum Infectious Diseases. 8:S637-S637
Background Obesity is a significant global health problem and has been associated with altered pharmacokinetics (PK) and pharmacodynamics (PD) of many drugs. Cephalexin is a commonly prescribed antibiotic as an oral drug for the treatment of mild to
Publikováno v:
The Journal of Clinical Pharmacology. 57:356-368
The study objective was to evaluate meropenem population pharmacokinetics and pharmacodynamics in nonobese, obese, and morbidly obese patients. Forty adult patients-11 nonobese (body mass index [BMI] MIC of 40%, 54%, and 100% of the dosing interval.
Publikováno v:
Open Forum Infectious Diseases
Background Dose optimization of antibiotics has been shown to increase the likelihood of achieving pharmacodynamic efficacy targets and improve clinical outcomes. For carbapenems, achieving greater than 40% time above minimum inhibitory concentration
Publikováno v:
The Annals of pharmacotherapy. 51(3)
Background: Doripenem population pharmacokinetics and dosing recommendations are limited in obesity. Objective: To evaluate the population pharmacokinetics and pharmacodynamics of doripenem in obese patients. Methods: Hospitalized adults with a body
Publikováno v:
Open Forum Infectious Diseases
Background In neutropenic patients, a fever may be the only indication of a severe underlying infection. According to the National Comprehensive Cancer Network (NCCN) guidelines, for high-risk patients, monotherapy with an anti-pseudomonal β-lactam
Autor:
Megan R. Fleming, S. Christian Cheatham, Melissa L. Humphrey, Katherine M. Shea, Michael B. Kays, Eun Kyoung Chung, Daniel P. Healy
Publikováno v:
The Journal of Clinical Pharmacology. 54:324-330
The study objective was to evaluate meropenem pharmacokinetics and pharmacodynamics in morbid obesity. Nine patients hospitalized in an intensive care unit with a body mass index ≥40 kg/m(2) received meropenem 500 mg or 1 g q6h, infused over 0.5 ho
Autor:
Timothy F Murrey, S. Christian Cheatham, Alicia Browning, Michael B. Kays, Daniel P. Healy, Eun Kyoung Chung, Andrea H. Stock, Maureen Campion, Julia Jeffery, Sara Utley, Matthew F. Wack
Publikováno v:
Open Forum Infectious Diseases. 3
Optimization of Pneumonia Treatment in an Intensive Care Unit Utilizing a Pharmacist-Driven Protocol
Autor:
S. Christian Cheatham, Andrea H. Stock, Maureen Campion, Kevin Sponsel, Richard Need, Imad Shawa
Publikováno v:
Open Forum Infectious Diseases. 3
Autor:
Michael B. Kays, David W. Smith, Megan R. Fleming, Matthew F. Wack, S. Christian Cheatham, Kevin M. Sowinski, Melissa L. Humphrey, Katherine M. Shea, Daniel P. Healy
Publikováno v:
International Journal of Antimicrobial Agents. 37:46-50
The objective of this study was to evaluate the steady-state pharmacokinetics and pharmacodynamics of cefepime administered by prolonged infusion in hospitalised patients requiring antimicrobial therapy. Nine patients received 1g every 8h (q8h), infu