Zobrazeno 1 - 10
of 120
pro vyhledávání: '"S. Cholerton"'
Autor:
Alan V. Boddy, L Price, I Willits, Andrew D.J. Pearson, Michael J. Tilby, S. Cholerton, Annie Parry, Dianne Ford
Publikováno v:
British Journal of Cancer
The degree of damage to DNA following ifosfamide (IFO) treatment may be linked to the therapeutic efficacy. The pharmacokinetics and metabolism of IFO were studied in 19 paediatric patients, mostly with rhabdomyosarcoma or Ewings sarcoma. Ifosfamide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e69e540e3860500b27cc40720b62f7d0
https://doi.org/10.1038/sj.bjc.6602554
https://doi.org/10.1038/sj.bjc.6602554
Autor:
Atilla Halil Elhan, Neslihan Aygun Kocabas, Semra Sardas, Ali Esat Karakaya, S. Cholerton, Ann K. Daly
Publikováno v:
Cell Biochemistry and Function. 23:73-76
Within mitochondria, manganese superoxide dismutase (MnSOD) provides a major defence against oxidative damage by reactive oxygen species (ROS). An alanine-9valine (Ala-9Val) polymorphism in the mitochondrial targeting sequence of MnSOD has been descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451f8789d8e1b40e6580adb1d2c9cd94
https://doi.org/10.1002/cbf.1128
https://doi.org/10.1002/cbf.1128
Publikováno v:
Archives of Toxicology. 76:643-649
Epidemiological studies indicate that most risk factors for breast cancer are related to reproductive and hormonal factors. Estrogen has been proposed to trigger breast cancer development via an initiating mechanism involving its metabolite, catechol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d378ba79f9f657bf8474c525ff252ae
https://doi.org/10.1007/s00204-002-0387-x
https://doi.org/10.1007/s00204-002-0387-x
Publikováno v:
Pharmacogenetics. 7:411-414
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4866c58beddf341bc07dc809a18bbfdb
https://doi.org/10.1097/00008571-199710000-00012
https://doi.org/10.1097/00008571-199710000-00012
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 575:325-330
A novel method for the determination of 7-hydroxycoumarin in human urine which combines thin-layer chromatography (TLC) with fluorescence detection (FD) has been devised. The limit of detection (1 ng/ml) enables determination of 7-hydroxycoumarin aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2d8af0994b48046d549526b71a2a3a
https://doi.org/10.1016/0378-4347(92)80166-n
https://doi.org/10.1016/0378-4347(92)80166-n
Publikováno v:
Clinical Hemorheology and Microcirculation. 11:441-446
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37b61f494d158c72c424ec9b8e978dee
https://doi.org/10.3233/ch-1991-11521
https://doi.org/10.3233/ch-1991-11521
Publikováno v:
Pharmacogenetics. 6:261-263
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfaa8468cb005dd7ae0be0ee858e556f
https://doi.org/10.1097/00008571-199606000-00010
https://doi.org/10.1097/00008571-199606000-00010
Publikováno v:
International journal of toxicology. 23(1)
Increased exposure to environmental carcinogens, including several aromatic and heterocyclic amines (HAs), is suspected to be one factor contributing to incidence of breast cancer. The N-acetyltransferase 2 ( NAT2) acetylation polymorphism have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8b42119fcf3ee66b558f14d6caca94
https://pubmed.ncbi.nlm.nih.gov/15162844
https://pubmed.ncbi.nlm.nih.gov/15162844
Autor:
S. Cholerton, Shannon Atkinson, Yacoub M. Irshaid, N. M. Rawashdeh, H Hadidi, Jeffrey R. Idle
Publikováno v:
Scopus-Elsevier
The ability to oxidise trimethylamine (TMA) to trimethylamine N-oxide (TMAO) is distributed polymorphically within a British white population with the majority of individuals excreting greater than 90% of total urinary TMA as TMAO. The opposite extre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f3c9d4bee21b5be6507c408dff646b
https://doi.org/10.1111/j.1365-2125.1995.tb04427.x
https://doi.org/10.1111/j.1365-2125.1995.tb04427.x
