Zobrazeno 1 - 10
of 455
pro vyhledávání: '"S. Chappell"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Dysfunction of both microglia and circuitry in the medial prefrontal cortex (mPFC) have been implicated in numerous neuropsychiatric disorders, but how microglia affect mPFC development in health and disease is not well understood. mPFC circuits unde
Externí odkaz:
https://doaj.org/article/1b2ffc277e974e5280242985b450c237
Autor:
Robert R. Edwards, Robert H. Dworkin, Dennis C. Turk, Martin S. Angst, Raymond Dionne, Roy Freeman, Per Hansson, Simon Haroutounian, Lars Arendt-Nielsen, Nadine Attal, Ralf Baron, Joanna Brell, Shay Bujanover, Laurie B. Burke, Daniel Carr, Amy S. Chappell, Penney Cowan, Mila Etropolski, Roger B. Fillingim, Jennifer S. Gewandter, Nathaniel P. Katz, Ernest A. Kopecky, John D. Markman, George Nomikos, Linda Porter, Bob A. Rappaport, Andrew S.C. Rice, Joseph M. Scavone, Joachim Scholz, Lee S. Simon, Shannon M. Smith, Jeffrey Tobias, Tina Tockarshewsky, Christine Veasley, Mark Versavel, Ajay D. Wasan, Warren Wen, David Yarnitsky
Publikováno v:
PAIN Reports, Vol 6, Iss 1, p e899 (2021)
Abstract. There is tremendous interpatient variability in the response to analgesic therapy (even for efficacious treatments), which can be the source of great frustration in clinical practice. This has led to calls for “precision medicine” or pe
Externí odkaz:
https://doaj.org/article/daf3aa186f274684ac1ec5b80f599fe5
Autor:
Madison Bolger-Munro, Kate Choi, Joshua M Scurll, Libin Abraham, Rhys S Chappell, Duke Sheen, May Dang-Lawson, Xufeng Wu, John J Priatel, Daniel Coombs, John A Hammer, Michael R Gold
Publikováno v:
eLife, Vol 8 (2019)
When B cells encounter antigens on the surface of an antigen-presenting cell (APC), B cell receptors (BCRs) are gathered into microclusters that recruit signaling enzymes. These microclusters then move centripetally and coalesce into the central supr
Externí odkaz:
https://doaj.org/article/495108e2d3d348008c7a1f7e3b66fd17
Autor:
Juntao (Matt) Mai, Kate Caldwell, Lindsay DeVorkin, Grace P. Leung, Karine Herve, Yuri Hwang, Cristina Faralla, Wei Wei, Emma Lathouwers, Valentine de Puyraimond, Lauren Clifford, Rhys S. Chappell, Stefan Hannie, Katherine J. Lam, Harveer Dhupar, Tran N. Tran, Melissa Cid, Lena M. Bolten, Tova Pinsky, Ping Xiang, Courteney Lai, Ahn Lee, Vivian Z. Li, Patrick Chan, Jasmine Chin, Steve Booth, Amy C. Lee, Stephanie Masterman, Sherie Duncan, Aaron Yamniuk, Kush Dalal, Tim M. Jacobs, Raffi Tonikian, Bryan C. Barnhart
Publikováno v:
Cancer Research. 83:1886-1886
In this study, we describe the characterization and validation of a diverse panel of fully human CD3-binding antibodies, including hundreds of human and cyno cross-reactive binders. We used two proof-of-concept TCE targets to demonstrate that this pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47061b8b3f04aed268ae085c8e24ab8e
https://doi.org/10.1158/1538-7445.am2023-1886
https://doi.org/10.1158/1538-7445.am2023-1886
Publikováno v:
JOURNAL OF RADIOLOGICAL PROTECTION
In the few years leading up to this research, CLEAPSS noticed a small but steadily increasing number of calls from UK schools regarding a red-brown discolouration on the surface of the foil of their radium source. There were no reports of this type o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::addc0d0e1c98779a90c9495a2b7370d5
http://livrepository.liverpool.ac.uk/3152258/1/foil_degradation_ra226_v3b_accepted.pdf
http://livrepository.liverpool.ac.uk/3152258/1/foil_degradation_ra226_v3b_accepted.pdf
Publikováno v:
Journal of radiological protection : official journal of the Society for Radiological Protection. 42(2)
In the few years leading up to this research, CLEAPSS noticed a small but steadily increasing number of calls from UK schools regarding a red-brown discolouration on the surface of the foil of their radium source. There were no reports of this type o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d094143231e1b3b39cd1f89a9edae648
https://pubmed.ncbi.nlm.nih.gov/35226882
https://pubmed.ncbi.nlm.nih.gov/35226882
Autor:
Amy S Chappell, Laurence A Bradley, Curtis Wiltse, Michael J Detke, Deborah N D’Souza, Michael Spaeth
Publikováno v:
International Journal of General Medicine, Vol 2008, Iss default, Pp 91-102 (2008)
Amy S Chappell1, Laurence A Bradley2, Curtis Wiltse1, Michael J Detke1,3,4, Deborah N D’Souza1, Michael Spaeth51Lilly Research Laboratories, Indianapolis, IN, USA; 2University of Alabama at Birmingham, Birmingham, Alabama, USA; 3Indiana University
Externí odkaz:
https://doaj.org/article/32bad8d79e144510927c33179e33c3d9
Autor:
Eric N. Moca, Daniela Lecca, Keenan T. Hope, Fanny Etienne, Ari W. Schaler, Katherine Espinoza, Megan S. Chappell, Daniel T. Gray, David Tweedie, Shanaya Sidhu, Lindsay Masukawa, Hannah Sitoy, Rose Mathew, Daniel R. Saban, Nigel H. Greig, Lindsay M. De Biase
Publikováno v:
J Neurosci
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 42, iss 19
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 42, iss 19
During aging, microglia produce inflammatory factors, show reduced tissue surveillance, altered interactions with synapses, and prolonged responses to CNS insults, positioning these cells to have profound impact on the function of nearby neurons. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb840805238903a1acfb9719505ca73
https://pubmed.ncbi.nlm.nih.gov/35396327
https://pubmed.ncbi.nlm.nih.gov/35396327
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