Zobrazeno 1 - 8
of 8
pro vyhledávání: '"S. Chakra Chennubhotla"'
Autor:
Shikhar Uttam, Andrew M. Stern, Christopher J. Sevinsky, Samantha Furman, Filippo Pullara, Daniel Spagnolo, Luong Nguyen, Albert Gough, Fiona Ginty, D. Lansing Taylor, S. Chakra Chennubhotla
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Spatial information in the tumour microenvironment may be exploited to optimise diagnosis, prognosis and therapy. Here, the authors develop a spatial analytics computational and systems pathology platform (SpAn) based on highly multiplexed antibody i
Externí odkaz:
https://doaj.org/article/a43bb54843794cb1bbe267661f6d6f4c
Autor:
Anda Trifan, Defne Gorgun, Michael Salim, Zongyi Li, Alexander Brace, Maxim Zvyagin, Heng Ma, Austin Clyde, David Clark, David J Hardy, Tom Burnley, Lei Huang, John McCalpin, Murali Emani, Hyenseung Yoo, Junqi Yin, Aristeidis Tsaris, Vishal Subbiah, Tanveer Raza, Jessica Liu, Noah Trebesch, Geoffrey Wells, Venkatesh Mysore, Thomas Gibbs, James Phillips, S Chakra Chennubhotla, Ian Foster, Rick Stevens, Anima Anandkumar, Venkatram Vishwanath, John E Stone, Emad Tajkhorshid, Sarah A Harris, Arvind Ramanathan
Publikováno v:
The International Journal of High Performance Computing Applications. 36:603-623
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) replication transcription complex (RTC) is a multi-domain protein responsible for replicating and transcribing the viral mRNA inside a human cell. Attacking RTC function with pharmaceut
Publikováno v:
Cancer Research. 83:P6-04
Background: Pathologists typically diagnose the breast tissue slides under a microscope by examining: (i) lumen and ductal morphology, (ii) nuclei size, shape, and spatial arrangement and their combinations, (iii) intraductal architecture, and (iv) t
Autor:
Samantha Panakkal, Brian Falkenstein, Akif Burak Tosun, Bruce Campbell, Michael Becich, Jeffrey Fine, D. Lansing Taylor, S. Chakra Chennubhotla, Filippo Pullara
Publikováno v:
Cancer Research. 82:454-454
Background: The current computational analyses of multi to hyperplexed fluorescence and/or mass spectrometry image datasets from patient pathology samples are not powerful enough to extract the maximum amount of information or to create the detailed
Autor:
Daniel M Spagnolo, Rekha Gyanchandani, Yousef Al-Kofahi, Andrew M Stern, Timothy R Lezon, Albert Gough, Dan E Meyer, Fiona Ginty, Brion Sarachan, Jeffrey Fine, Adrian V Lee, D Lansing Taylor, S Chakra Chennubhotla
Publikováno v:
Journal of Pathology Informatics, Vol 7, Iss 1, Pp 47-47 (2016)
Background: Measures of spatial intratumor heterogeneity are potentially important diagnostic biomarkers for cancer progression, proliferation, and response to therapy. Spatial relationships among cells including cancer and stromal cells in the tumor
Externí odkaz:
https://doaj.org/article/0133c569b3f04299ad5b8fe46e6286f6
Akademický článek
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Akademický článek
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Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220037 (2019)
Human genome contains a group of more than a dozen similar genes with diverse biological functions including antiviral, antibacterial and angiogenesis activities. The characterized gene products of this group show significant sequence similarity and
Externí odkaz:
https://doaj.org/article/c662350ee8ab44b9a84060b15e627ce8