Zobrazeno 1 - 10
of 38
pro vyhledávání: '"S. Caxaria"'
Publikováno v:
Curr Opin Support Palliat Care
PURPOSE OF REVIEW Osteoarthritis is a degenerative joint disease that features pain as a hallmark symptom. This review summarises progress and obstacles in our understanding of pain mechanisms in arthritis. RECENT FINDINGS Pain phenotypes in osteoart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6283c8dd7fd6f3ba6bf2bd28cacf9767
https://europepmc.org/articles/PMC7610722/
https://europepmc.org/articles/PMC7610722/
Autor:
James G. Nicholson, Costantino Pitzalis, Alison Maloney, Mario Alvarez, S.E. Eldridge, Carles Gaston-Massuet, Ray Jupp, G. Nalesso, B.L. Thomas, Babak Nosrati, Adrian Moore, Mauro Perretti, Anne-Sophie Thorup, Aida Barawi, Francesco Dell'Accio, S. Caxaria
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 7, Pp n/a-n/a (2021)
Journal of Extracellular Vesicles
Journal of Extracellular Vesicles
Cartilage defects repair poorly. Recent genetic studies suggest that WNT3a may contribute to cartilage regeneration, however the dense, avascular cartilage extracellular matrix limits its penetration and signalling to chondrocytes. Extracellular vesi
Autor:
A.-S. Thorup, J. Wilson, D. Strachan, S. Caxaria, B. Poulet, B. Thomas, S. Eldridge, G. Nalesso, J. Whiteford, C. Pitzalis, T. Aigner, R. Corder, J. Bertrand, S. Lohmander, P. Cutillas, F. Dell'Accio
Publikováno v:
Osteoarthritis and Cartilage. 30:S159
Autor:
Magdalena Kaneva, B.L. Thomas, D. Strachan, Anne-Sophie Thorup, S. Caxaria, Kanatheepan Shanmuganathan, Anke J. Roelofs, Ahmed Ali, S.E. Eldridge, Andrew McCaskie, Aida Barawi, Costantino Pitzalis, James R. Whiteford, Francesco Dell'Accio, Beatriz F. Fernandez, Frances Henson, Helen Lydon, H. Wang, Zeyu Guan, Cosimo De Bari
Cartilage loss leads to osteoarthritis, the most common cause of disability for which there is no cure. Cartilage regeneration, therefore, is a priority in medicine. We report that agrin is a potent chondrogenic factor and that a single intraarticula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b385b6448cc7ad68bf28553aa31d2c
Autor:
Thomas Aigner, B.L. Thomas, S.E. Eldridge, James R. Whiteford, Blandine Poulet, Roger Corder, Anne-Sophie Thorup, Francesco Dell'Accio, S. Caxaria, Costantino Pitzalis, Jessica Bertrand, D. Strachan, G. Nalesso
Publikováno v:
Science Translational Medicine
Osteoarthritis is characterized by the loss of the articular cartilage, bone remodeling, pain, and disability. No pharmacological intervention can currently halt progression of osteoarthritis. Here, we show that blocking receptor tyrosine kinase–li
Akademický článek
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Autor:
Francesco Dell'Accio, S. Caxaria, James R. Whiteford, Thomas Aigner, D. Strachan, G. Nalesso, S.E. Eldridge, Jessica Bertrand, B.L. Thomas, Roger Corder, Anne-Sophie Thorup, Blandine Poulet, C. Pitzalis
Publikováno v:
Annals of the Rheumatic Diseases. 80:120.1-121
Background:Osteoarthritis (OA) is the leading cause of chronic disability worldwide, affecting 12% of the population, and yet we still do not have a disease-modifying treatment. Cartilage breakdown is the hallmark of OA, and patients suffer from pain
Autor:
B.L. Thomas, Anke J. Roelofs, S.E. Eldridge, Ahmed Ali, Aida Barawi, K. Shanmuganathan, Magdalena Kaneva, Zeyu Guan, C. De Bari, Andrew McCaskie, S. Caxaria, Francesco Dell'Accio, Anne-Sophie Thorup, H. Wang, D. Strachan, Costantino Pitzalis, James R. Whiteford, Helen Lydon, Beatriz F. Fernandez, Frances Henson
Publikováno v:
Annals of the Rheumatic Diseases. 80:1052.1-1052
Background:Cartilage defects in the joints are reported in 61% of all arthroscopies1&2. The size of the cartilage repair market is estimated to be $2.195 million by 20253. Cartilage defects can evolve into osteoarthritis, in which abnormal load resul
Akademický článek
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