Zobrazeno 1 - 10
of 48
pro vyhledávání: '"S. Carteau"'
Autor:
Christian Auclair, Bernard P. Roques, J L Darlix, S C Batson, Jean-François Mouscadet, L Poljak, E Käs, H. De Rocquigny, S. Carteau
Publikováno v:
Journal of Virology. 71:6225-6229
The integrase (IN) protein of the human immunodeficiency virus mediates integration of the viral DNA into the cellular genome. In vitro, this reaction can be mimicked by using purified recombinant IN and model DNA substrates. IN mediates two reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::245a368b9fc3ab33ce4a0a39d5fce1e9
https://doi.org/10.1128/jvi.71.8.6225-6229.1997
https://doi.org/10.1128/jvi.71.8.6225-6229.1997
Autor:
M. Le Bret, Jean-François Mouscadet, F. Subra, Hélène Goulaouic, Christian Auclair, C. Ketterle, S. Carteau
Publikováno v:
Biochemistry. 33:4187-4196
In an attempt to target short purine sequences in view of pharmacological application, we have synthesized three new TFO (triple-helix-forming oligonucleotide) conjugates in which an intercalating oxazolopyridocarbazole (OPC) chromophore is linked by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d6b1d9bb5ee062eea2b7c6b402cbf7
https://doi.org/10.1021/bi00180a011
https://doi.org/10.1021/bi00180a011
Publikováno v:
Virology. 200:87-97
We studied Moloney murine leukemia virus replication in newly infected Balb c/3T3 cells brought to the G0 phase by serum depletion. Using the polymerase chain reaction method, we showed that Moloney murine leukemia virus can be efficiently internaliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5c47cbe78c46659977d3cf3772860c
https://doi.org/10.1006/viro.1994.1166
https://doi.org/10.1006/viro.1994.1166
Autor:
Jean-François Mouscadet, Jian Sheng Sun, S. Carteau, Frédéric Subra, Hélène Goulaouic, Christian Auclair
Publikováno v:
Biochemistry. 33:1412-1418
In order to further characterize the binding of the hybrid molecule NetOPC [bis(pyrrolecarboxamide)-oxazolopyridocarbazole conjugate] to double-stranded DNA, we have performed a molecular modeling study to investigate the binding modes of the complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a687d1e9bb6d3f170b1d0053400a67d
https://doi.org/10.1021/bi00172a018
https://doi.org/10.1021/bi00172a018
Publikováno v:
Biochemical and Biophysical Research Communications. 192:1409-1414
Retroviral growth requires as an obligatory step the integration of a DNA copy of the viral RNA into the genomic DNA of the host. Recombinant human immunodeficiency virus type I (HIV-1) integrase (IN) expressed in Escherichia coli efficiently catalyz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f11e0923401bd2993b8b5b4036f703fd
https://doi.org/10.1006/bbrc.1993.1573
https://doi.org/10.1006/bbrc.1993.1573
Autor:
Gilles Gosselin, Jacques Paoletti, Frédéric Subra, Jeanne Pager, Jean Louis Imbach, D Mrani, S. Carteau, Claude Paoletti, Christian Auclair
Publikováno v:
Biochemistry. 30:1642-1650
We have investigated some properties related to interaction with DNA and recognition of AT-rich sequences of netropsin-oxazolopyridocarbazole (Net-OPC) (Mrani et al., 1990), which is a hybrid groove-binder-intercalator. The hybrid molecule Net-OPC bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e975961d6b568e2457afea4fd6adc869
https://doi.org/10.1021/bi00220a029
https://doi.org/10.1021/bi00220a029
Publikováno v:
Genetic engineering. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f20b670fb80793ef012d9f85a2afbcbe
https://pubmed.ncbi.nlm.nih.gov/9666555
https://pubmed.ncbi.nlm.nih.gov/9666555
Publikováno v:
Cancer research. 55(14)
The possible intervention of nuclear proteins as cofactors of integrase-catalyzed integration of retroviral DNA into the host cell genome is not fully understood. Among various nuclear proteins, DNA topoisomerase II appears to be a plausible candidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab46220d724989e919245590b737e91e
https://pubmed.ncbi.nlm.nih.gov/7606743
https://pubmed.ncbi.nlm.nih.gov/7606743
Publikováno v:
Biochemical pharmacology. 47(10)
In search of potential inhibitors of integration of retroviral DNA into host cells genome, we have investigated the effect of the external DNA binder netropsin on the in vitro insertion of long terminal repeat (LTR) ends of Moloney murine leukemia vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5f76c748ec1d4aee08d958fc9f7bb4
https://pubmed.ncbi.nlm.nih.gov/8204098
https://pubmed.ncbi.nlm.nih.gov/8204098
Publikováno v:
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. 317(5)
Combinations of ddC with either the ribonucleotide reductase inhibitor hydroxyurea (HU) or with the natural nucleoside thymidine have been investigated on the cycle of a defective (psi neo) Moloney Leukemia Virus (MoMLV) using 3T3 fibroblasts as host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9490fe4a7b6d66d8de3a98e807e7ba66
https://pubmed.ncbi.nlm.nih.gov/7994621
https://pubmed.ncbi.nlm.nih.gov/7994621