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Phage-based assay for rapid detection of bacterial pathogens in blood by Raman spectroscopy

Autor: Domenico Franco, Maria Rizzo, Enza Fazio, Salvatore P.P. Guglielmino, Fortunato Neri, Sebastiano Trusso, S. Carnazza, Laura M. De Plano

Publikováno v: Journal of immunological methods
465 (2019): 45–52. doi:10.1016/j.jim.2018.12.004
info:cnr-pdr/source/autori:De Plano, Laura M.; Fazio, Enza; Rizzo, Maria Giovanna; Franco, Domenico; Carnazza, Santina; Trusso, Sebastiano; Neri, Fortunato; Guglielmino, Salvatore P.P./titolo:Phage-based assay for rapid detection of bacterial pathogens in blood by Raman spectroscopy/doi:10.1016%2Fj.jim.2018.12.004/rivista:Journal of immunological methods (Print)/anno:2019/pagina_da:45/pagina_a:52/intervallo_pagine:45–52/volume:465

Sepsis is a systemic inflammatory response ensuing from presence and persistence of microorganisms in the bloodstream. The possibility to identify them at low concentrations may improve the problem of human health and therapeutic outcomes. So, sensit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::325f731d61ee5fb3d5d906720e0630b8
https://doi.org/10.1016/j.jim.2018.12.004

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Specific and selective probes for Staphylococcus aureus from phage-displayed random peptide libraries

Autor: Grazia M. L. Messina, Salvatore P.P. Guglielmino, S. Carnazza, Maria Rizzo, Laura M. De Plano, Giovanni Marletta

Publikováno v: Colloids and Surfaces B: Biointerfaces. 157:473-480

Staphylococcus aureus is a major human pathogen causing health care-associated and community-associated infections. Early diagnosis is essential to prevent disease progression and to reduce complications that can be serious. In this study, we selecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e52dda6190670072eeb147d08bec70
https://doi.org/10.1016/j.colsurfb.2017.05.081

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Rapid detection of bacterial pathogens in blood through engineered phages-beads and integrated Real-Time PCR into MicroChip

Autor: Sabrina Conoci, Salvatore P.P. Guglielmino, L.M. De Plano, S. Carnazza, Marco Sebastiano Nicolò, Salvatore Petralia, Concetta Gugliandolo, Vincenzo Zammuto, Domenico Franco, Maria Rizzo, Giovanna Calabrese

Publikováno v: Sensors and Actuators B: Chemical. 329:129227

The invasion of pathogens into the bloodstream can produce a systemic inflammatory response syndrome that, if not promptly treated, rapidly evolves in acute life-threatening dysfunction of remote organs (septic shock). Current conventional diagnostic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5cdc9cc5286c7f551237a636ca12007
https://doi.org/10.1016/j.snb.2020.129227

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Antibiotic-loaded nanoparticles targeted to the site of infection enhance antibacterial efficacy

Autor: Tarmo Mölder, Jinyoung Kang, Dokyoung Kim, Sajid Hussain, Gary B. Braun, Zhi-Gang She, Tambet Teesalu, Salvatore P.P. Guglielmino, Byungji Kim, Erkki Ruoslahti, Jinmyoung Joo, Michael J. Sailor, S. Carnazza, Aman P. Mann

Bacterial resistance to antibiotics has made it necessary to resort to using antibacterial drugs that have considerable toxicities. Here, we show that conjugation of vancomycin-loaded nanoparticles with the cyclic 9-amino-acid peptide CARGGLKSC (CARG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c243ab78560cee754e53d039ab5be0cf
https://europepmc.org/articles/PMC6015743/

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ToF-SIMS imaging of surface self-organized fractal patterns of bacteria

Autor: S. Carnazza, M. Caratozzolo, L. Grasso, Antonino Licciardello, Giovanni Marletta, Nunzio Tuccitto, Salvatore P.P. Guglielmino

Publikováno v: Surface and Interface Analysis. 43:370-375

Time-of-flight secondary ion mass spectrometry (ToF-SIMS) imaging has been shown to be a useful tool to study cell adhesion onto a surface. The purpose of this work was that of investigating by means of ToF-SIMS imaging the influence of different sal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9069d8b578dca0fed8a7bebef0a79200
https://doi.org/10.1002/sia.3555

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Phage-coated paramagnetic beads as selective and specific capture system for biosensor applications

Autor: L.M. De Plano, S. Carnazza, Germana Lentini, Domenico Franco, Salvatore P.P. Guglielmino, Federica Calabrese

M13 bacteriophage, engineered to express specific and selective peptides on its capsid proteins, can be used as a good substitute for antibodies in recognition of specific targets showing at the same time thermal and mechanical resistance, strength a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e6d17fb3ff7f571c7399ddfbccac84
http://hdl.handle.net/11570/3061739

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Phage-AgNPs complex as SERS probe for U937 cell identification

Autor: Sebastiano Trusso, Caterina Musolino, Salvatore P.P. Guglielmino, Fortunato Neri, Federica Calabrese, Maria Puliafico, Enza Fazio, Alessandro Allegra, Domenico Franco, Germana Lentini, Marco Sebastiano Nicolò, Laura M. De Plano, S. Carnazza

Publikováno v: Biosensors & bioelectronics 74 (2015): 398–405. doi:10.1016/j.bios.2015.05.073
info:cnr-pdr/source/autori:Lentini, Germana; Fazio, Enza; Calabrese, Federica; De Plano, Laura M.; Puliafico, Maria; Franco, Domenico; Nicolo, Marco S.; Carnazza, Santina; Trusso, Sebastiano; Allegra, Alessandro; Neri, Fortunato; Musolino, Caterina; Guglielmino, Salvatore P. P./titolo:Phage-AgNPs complex as SERS probe for U937 cell identification/doi:10.1016%2Fj.bios.2015.05.073/rivista:Biosensors & bioelectronics/anno:2015/pagina_da:398/pagina_a:405/intervallo_pagine:398–405/volume:74

The early diagnosis of malignancy is the most critical factor for patient survival and the treatment of cancer. In particular, leukemic cells are highly heterogeneous, and there is a need to develop new rapid and accurate detection systems for early

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::751f2243bfe3d166f0a960dedef55f65
http://hdl.handle.net/11570/3061196

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Cell adhesion and spreading on polymer surfaces micropatterned by ion beams

Autor: Cristina Satriano, Giovanni Marletta, Antonino Licciardello, Salvatore P.P. Guglielmino, S. Carnazza

Publikováno v: Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films. 21:1145-1151

The cell adhesion and spreading behavior on surfaces of poly(ethyleneterephtalate) and poly(hydroxymethylsiloxane) micropatterned by focused 15 keV Ga+ beams has been studied. It has been found that while no modification in the cell adhesion process

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db632956b8889d8b927f166370f51656
https://doi.org/10.1116/1.1575217

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[Untitled]

Autor: S. Carnazza, Giovanni Marletta, Cristina Satriano, Salvatore P.P. Guglielmino

Publikováno v: Journal of Materials Science: Materials in Medicine. 14:663-670

A very peculiar case of differential cell response towards polysiloxane surfaces of very similar composition is investigated. Poly(hydroxymethylsiloxane) (PHMS) surfaces treated either by O2-plasma or 6 keV Ar+-beams have been used to test the adhesi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a64c0669ef780afbfc2314a96adb9812
https://doi.org/10.1023/a:1024999213426

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