Zobrazeno 1 - 10
of 20
pro vyhledávání: '"S. C. Sikka"'
Autor:
Ming Li, Dingwu Jia, Xiangbin Zeng, S C Sikka, C Sun, C Xu, Luping Huang, Jonathan E. Pottle, James T. Taylor, A B Abdel-Mageed
Publikováno v:
Prostate Cancer and Prostatic Diseases
We have identified a novel function for a member of the transient receptor potential (TRP) protein super-family, TRPM2, in prostate cancer cell proliferation. TRPM2 encodes a non-selective cation-permeable ion channel. We found that selectively knock
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607727b278e0b01eee99a23c516e9168
https://doi.org/10.1038/pcan.2009.55
https://doi.org/10.1038/pcan.2009.55
Autor:
A. Gokce, Gökçe, Ahmet, Z. Y. Abd Elmageed, G. F. Lasker, M. Bouljihad, H. Kim, L. W. Trost, P. J. Kadowitz, A. B. Abdel-Mageed, S. C. Sikka, W. J. Hellstrom
Publikováno v:
Andrology. 2(2)
Peyronie's disease (PD) is a localized connective tissue disorder that involves the tunica albuginea (TA) of the penis. While surgical correction remains the gold standard, the search for an effective and less invasive therapy continues. The objectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b8189bb40a3eaab63a4feb7458b12d
https://pubmed.ncbi.nlm.nih.gov/24574095
https://pubmed.ncbi.nlm.nih.gov/24574095
Nitric oxide induces oxidative stress and mediates cytotoxicity to human cavernosal cells in culture
Publikováno v:
Journal of andrology. 22(1)
Nitric oxide (NO) is a product of nitric oxide synthase (NOS) activity and is recognized as the main mediator of penile erection by induction of cavernosal smooth muscle relaxation. Although excessive NO can be generated via inducible NOS activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::88c442d95dc95cd79c1841f858245565
https://pubmed.ncbi.nlm.nih.gov/11191085
https://pubmed.ncbi.nlm.nih.gov/11191085
Autor:
T J, Bivalacqua, H C, Champion, M, Rajasekaran, S C, Sikka, P J, Kadowitz, P C, Doherty, W J, Hellstrom
Publikováno v:
The Journal of urology. 162(5)
Phosphodiesterases (PDEs) are an important component of the signal transduction pathway during the erectile response. To determine the PDE isoforms in the corpora cavernosa in the cat and to establish the functional presence of PDE 4 in human caverno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a154fb4e0839ae3e2de847fdd9a4335
https://pubmed.ncbi.nlm.nih.gov/10524946
https://pubmed.ncbi.nlm.nih.gov/10524946
Publikováno v:
Journal of andrology. 20(4)
Intralesional therapy is a less invasive method for the treatment of Peyronie's disease. The objective of this study was to evaluate intralesional injections of interferon alpha 2B (IFN-alpha-2B) as an effective alternative to the surgical treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75340a6df9b38a267ed585012a896b00
https://pubmed.ncbi.nlm.nih.gov/10452584
https://pubmed.ncbi.nlm.nih.gov/10452584
Autor:
T J, Bivalacqua, M, Rajasekaran, H C, Champion, R, Wang, S C, Sikka, P J, Kadowitz, W J, Hellstrom
Publikováno v:
Journal of andrology. 19(5)
The purpose of this study was to investigate the in vivo effects of intracavernosal injections of adrenomedullin (ADM), calcitonin gene-related peptide (CGRP), nociceptin, vasoactive intestinal polypeptide (VIP), sodium nitroprusside (SNP), and prost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::910a54992f7987a60fe916c997be7c55
https://pubmed.ncbi.nlm.nih.gov/9796614
https://pubmed.ncbi.nlm.nih.gov/9796614
Publikováno v:
Journal of andrology. 19(4)
Human serum albumin (HSA) is being considered as an alternate media for sperm enrichment in assisted reproductive technology (ART) because of recent concern with the use of Percoll. In this study, we compared HSA and Percoll for 1) sperm recovery, 2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::563802270c6adff450f458741d70d5fa
https://pubmed.ncbi.nlm.nih.gov/9733143
https://pubmed.ncbi.nlm.nih.gov/9733143
Publikováno v:
Journal of andrology. 16(6)
Oxygen toxicity is an inherent challenge to aerobic life, including spermatozoa, the cells responsible for propagation of the species. How this toxicity affects the spermatozoan in its interactions with the ovum is still unknown. An increase in oxida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0468cf2f5d94ded3a0d3bb7a0a414240
https://pubmed.ncbi.nlm.nih.gov/8867595
https://pubmed.ncbi.nlm.nih.gov/8867595
Publikováno v:
Fertility and sterility. 64(1)
To quantify the levels of reactive oxygen species, superoxide dismutase (SOD), and interleukins (IL) 2 and 8 in seminal plasma of infertile patients as well as to examine the possible relationship between oxidative stress and proinflammatory cytokine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b931b8badb9453901185e882be39ac0d
https://pubmed.ncbi.nlm.nih.gov/7789553
https://pubmed.ncbi.nlm.nih.gov/7789553
Publikováno v:
Journal of andrology. 15(2)
This in vitro study was conducted to determine the direct effects of electric current and associated increase in temperature on human sperm. Washed sperm samples from normal volunteers were subjected to an electric current (0 to 100 mA) in a small, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f3da8aaf84b9c8b524d1990271bb9110
https://pubmed.ncbi.nlm.nih.gov/8056638
https://pubmed.ncbi.nlm.nih.gov/8056638