Zobrazeno 1 - 10
of 16
pro vyhledávání: '"S. C. Helfand"'
Publikováno v:
Veterinary and Comparative Oncology. 10:214-222
Canine hemangiosarcoma (HSA) is an endothelial cell malignancy driven, in part, by activating mutations in receptor and non-receptor tyrosine kinases. Proteomics, Western blots and a tyrosine kinase inhibitor were used to elucidate activating mechani
Publikováno v:
Veterinary and Comparative Oncology. 1:94-104
The medical records of 15 dogs with anal sac adenocarcinoma (ASAC) treated with concurrent curative-intent radiotherapy and mitoxantrone (MX) after surgical removal of the primary tumour were reviewed retrospectively. Radiation was prescribed at 15 d
Publikováno v:
Veterinary and comparative oncology. 10(3)
Canine hemangiosarcoma (HSA) is an endothelial cell malignancy driven, in part, by activating mutations in receptor and non-receptor tyrosine kinases. Proteomics, Western blots and a tyrosine kinase inhibitor were used to elucidate activating mechani
Publikováno v:
Journal of Small Animal Practice. 35:320-325
Primary erythrocytosis was diagnosed in six adult neutered domestic cats. All the cats showed varying signs of neurological dysfunction, including seizures, blindness, abnormal behaviour, episodes of ataxia, dilated pupils and foaming at the mouth. O
Publikováno v:
Journal of Veterinary Internal Medicine. 4:187-191
Fifteen dogs with relapsed lymphoma were treated with doxorubicin and dacarbazine (ADIC) to reinduce remission. All the dogs' lymphomas had become resistant to prior therapy with doxorubicin alone. Five of the 15 dogs had a complete response to the f
Autor:
I D, Kurzman, E G, MacEwen, R C, Rosenthal, L E, Fox, E T, Keller, S C, Helfand, D M, Vail, R R, Dubielzig, B R, Madewell, C O, Rodriguez
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 1(12)
Two randomized, double-blind clinical trials in dogs with spontaneous appendicular osteosarcoma treated with combination chemoimmunotherapy are reported. In both trials, dogs without overt metastasis underwent complete amputation of the affected limb
Autor:
D M, Vail, E G, MacEwen, I D, Kurzman, R R, Dubielzig, S C, Helfand, W C, Kisseberth, C A, London, J E, Obradovich, B R, Madewell, C O, Rodriguez
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 1(10)
Canine splenic hemangiosarcoma (HSA) is a spontaneous tumor with high metastatic potential. Despite surgical excision, most dogs die within 2 months of diagnosis as a result of widespread visceral metastasis. This study was designed to determine the
Autor:
S C, Helfand, J F, Modiano, P F, Moore, S A, Soergel, P S, MacWilliams, R D, Dubielzig, J A, Hank, E W, Gelfand, P M, Sondel
Publikováno v:
Blood. 86(2)
We identified a dog with large granular lymphocytic leukemia and cutaneous lymphoma that exhibited constitutive expression of interleukin-2 (IL-2) receptors by the leukemic peripheral blood lymphocytes. The leukemic cells phenotypically resembled nat
Publikováno v:
Journal of the American Veterinary Medical Association. 204(3)
A mixed-breed dog, evaluated because of a chronic history of diarrhea and intestinal bleeding, was found to have a multilobular mass involving the intestine. Surgical resection of the mass necessitated an ileocolic anastomosis. On the basis of histol
Publikováno v:
Journal of veterinary internal medicine. 7(6)
Sixteen dogs with a histologic diagnosis of hemangiosarcoma were treated with surgery and doxorubicin/cyclophosphamide. The patients' characteristics, ie, age, size, and breed, were similar to those of previous studies. Historic controls for surgery