Identification of imaging biomarkers for the assessment of tumour response to different treatments in a preclinical glioma model

Autor: A. Lo Dico 1, 2, C. Martelli 1, 2. S. Valtorta 3, 4, I. Raccagni 4, 5, C. Diceglie 1, 6, S. Belloli 3, U. Gianelli1 7, V. Vaira 7, 8, L. S. Politi 9, S. Bosari 1, 7, G. Lucignani 2, R.M. Moresco 4, L. Ottobrini 1, 3

Publikováno v: European journal of nuclear medicine and molecular imaging (Internet) 42 (2015): 1093–1105.. doi:10.1007/s00259-015-3040-7
info:cnr-pdr/source/autori:A. Lo Dico 1,2, C. Martelli 1,2. S. Valtorta 3,4, I. Raccagni 4,5, C. Diceglie 1,6, S. Belloli 3,4, U. Gianelli1 7, V. Vaira 7,8, L. S. Politi 9, S. Bosari 1,7, G. Lucignani 2,10,11, R.M. Moresco 4,5, L. Ottobrini 1,2,3/titolo:Identification of imaging biomarkers for the assessment of tumour response to different treatments in a preclinical glioma model/doi:10.1007%2Fs00259-015-3040-7/rivista:European journal of nuclear medicine and molecular imaging (Internet)/anno:2015/pagina_da:1093/pagina_a:1105./intervallo_pagine:1093–1105./volume:42

Purpose: Hypoxia-inducible factor 1α (HIF-1α) activity is one of the major players in hypoxia-mediated glioma progression and resistance to therapies, and therefore the focus of this study was the evaluation of HIF-1α modulation in relation to tum

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