Zobrazeno 1 - 10
of 955
pro vyhledávání: '"S. Blackwell"'
Publikováno v:
Journal of Abdominal Wall Surgery, Vol 3 (2024)
Externí odkaz:
https://doaj.org/article/e0dbd802c6c548938e6a83be8885762f
A vital part of daily life in the nineteenth century, games and play were so familiar and so ubiquitous that their presence over time became almost invisible. Technological advances during the century allowed for easier manufacturing and distribution
Autor:
Gianluca T. DiGiovanni, Wei Han, Taylor P. Sherrill, Chase J. Taylor, David S. Nichols, Natalie M. Geis, Ujjal K. Singha, Carla L. Calvi, A. Scott McCall, Molly M. Dixon, Yang Liu, Ji-Hoon Jang, Sergey S. Gutor, Vasiliy V. Polosukhin, Timothy S. Blackwell, Jonathan A. Kropski, Jason J. Gokey
Publikováno v:
JCI Insight, Vol 8, Iss 19 (2023)
A hallmark of idiopathic pulmonary fibrosis (IPF) and other interstitial lung diseases is dysregulated repair of the alveolar epithelium. The Hippo pathway effector transcription factors YAP and TAZ are implicated as essential for type 1 and type 2 a
Externí odkaz:
https://doaj.org/article/953afc9fefaa496aab512cda2d374da2
Publikováno v:
EBioMedicine, Vol 95, Iss , Pp 104760- (2023)
Summary: Patients diagnosed with environmental/occupational bronchiolitis obliterans (BO) over the last 2 decades often present with an indolent evolution of respiratory symptoms without a history of high-level, acute exposure to airborne toxins. Exe
Externí odkaz:
https://doaj.org/article/4c54d0ab0a6340b69c9d212f36fa0b98
Autor:
Jennifer M.S. Sucre, Fabian Bock, Nicholas M. Negretti, John T. Benjamin, Peter M. Gulleman, Xinyu Dong, Kimberly T. Ferguson, Christopher S. Jetter, Wei Han, Yang Liu, Seunghyi Kook, Jason J. Gokey, Susan H. Guttentag, Jonathan A. Kropski, Timothy S. Blackwell, Roy Zent, Erin J. Plosa
Publikováno v:
JCI Insight, Vol 8, Iss 14 (2023)
During alveolar repair, alveolar type 2 (AT2) epithelial cell progenitors rapidly proliferate and differentiate into flat AT1 epithelial cells. Failure of normal alveolar repair mechanisms can lead to loss of alveolar structure (emphysema) or develop
Externí odkaz:
https://doaj.org/article/39a9e420f73c4111974b87e317b6ae4c
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2167 (2023)
Blood based traumatic brain injury (TBI) biomarkers offer additional diagnostic, therapeutic, and prognostic utility. While adult studies are robust, the pediatric population is less well studied. We sought to determine whether plasma osteopontin (OP
Externí odkaz:
https://doaj.org/article/85449b9c94b0430ebbec02efd24a1669
Autor:
Yang Jae Lee, Ibrahim Ssekalo, Rauben Kazungu, Timothy S. Blackwell, Jr., Peter Muwereza, Yuefeng Wu, José B. Sáenz
Publikováno v:
Heliyon, Vol 8, Iss 12, Pp e12612- (2022)
Background: Helicobacter pylori (H. pylori) infection and chronic dyspepsia represent significant medical burdens in the developing world. An accurate assessment of the prevalence of chronic dyspepsia, as well as of the effectiveness of population-ba
Externí odkaz:
https://doaj.org/article/dd05241307224228b3ddacaa2cf3111a
Autor:
Scott M. Haake, Erin J. Plosa, Jonathan A. Kropski, Lindsay A. Venton, Anupama Reddy, Fabian Bock, Betty T. Chang, Allen J. Luna, Kateryna Nabukhotna, Zhi-Qi Xu, Rebecca A. Prather, Sharon Lee, Harikrishna Tanjore, Vasiliy V. Polosukhin, Olga M. Viquez, Angela Jones, Wentian Luo, Matthew H. Wilson, W. Kimryn Rathmell, Pierre P. Massion, Ambra Pozzi, Timothy S. Blackwell, Roy Zent
Publikováno v:
JCI Insight, Vol 7, Iss 15 (2022)
Integrins — the principal extracellular matrix (ECM) receptors of the cell — promote cell adhesion, migration, and proliferation, which are key events for cancer growth and metastasis. To date, most integrin-targeted cancer therapeutics have disr
Externí odkaz:
https://doaj.org/article/265f440d006847c6922cd3a32eff3553
Autor:
Demetra H. Hufnagel, Andrew J. Wilson, Jamie Saxon, Timothy S. Blackwell, Jaclyn Watkins, Dineo Khabele, Marta A. Crispens, Fiona E. Yull, Alicia Beeghly-Fadiel
Publikováno v:
Biomarker Research, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Background The canonical and non-canonical nuclear factor-kappaB (NF-κB) signaling pathways have key roles in cancer, but studies have previously evaluated only the association of canonical transcription factors and ovarian cancer survival.
Externí odkaz:
https://doaj.org/article/64b228fc34df4340b790ce58498187c7
Autor:
Breanne H. Y. Gibson, Colby C. Wollenman, Stephanie N. Moore-Lotridge, Patrick R. Keller, J. Blair Summitt, Alexey R. Revenko, Matthew J. Flick, Timothy S. Blackwell, Jonathan G. Schoenecker
Publikováno v:
JCI Insight, Vol 6, Iss 23 (2021)
Severe injuries, such as burns, provoke a systemic inflammatory response syndrome (SIRS) that imposes pathology on all organs. Simultaneously, severe injury also elicits activation of the fibrinolytic protease plasmin. While the principal adverse out
Externí odkaz:
https://doaj.org/article/a90615824a274fa1b72ec0924b085a18