Zobrazeno 1 - 10
of 70
pro vyhledávání: '"S. Bjornsdottir"'
Autor:
Thorunn A. Olafsdottir, Gudmar Thorleifsson, Aitzkoa Lopez de Lapuente Portilla, Stefan Jonsson, Lilja Stefansdottir, Abhishek Niroula, Aslaug Jonasdottir, Hannes P. Eggertsson, Gisli H. Halldorsson, Gudny E. Thorlacius, Asgeir O. Arnthorsson, Unnur S. Bjornsdottir, Folkert W. Asselbergs, Arthur E. H. Bentlage, Gudmundur I. Eyjolfsson, Steinunn Gudmundsdottir, Kristbjorg Gunnarsdottir, Bjarni V. Halldorsson, Hilma Holm, Bjorn R. Ludviksson, Pall Melsted, Gudmundur L. Norddahl, Isleifur Olafsson, Saedis Saevarsdottir, Olof Sigurdardottir, Asgeir Sigurdsson, Robin Temming, Pall T. Önundarson, Unnur Thorsteinsdottir, Gestur Vidarsson, Patrick Sulem, Daniel F. Gudbjartsson, Ingileif Jonsdottir, Björn Nilsson, Kari Stefansson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Immunoglobulin G (IgG) is the main isotype of antibody in human blood. IgG consists of four subclasses (IgG1 to IgG4), encoded by separate constant region genes within the Ig heavy chain locus (IGH). Here, we report a genome-wide association
Externí odkaz:
https://doaj.org/article/355943621ae84500945b3eafee4e0e12
Autor:
Ragnar P. Kristjansson, Gudjon R. Oskarsson, Astros Skuladottir, Asmundur Oddsson, Solvi Rognvaldsson, Gardar Sveinbjornsson, Sigrun H. Lund, Brynjar O. Jensson, Edda L. Styrmisdottir, Gisli H. Halldorsson, Egil Ferkingstad, Grimur Hjorleifsson Eldjarn, Doruk Beyter, Snædis Kristmundsdottir, Kristinn Juliusson, Run Fridriksdottir, Gudny A. Arnadottir, Hildigunnur Katrinardottir, Margret H. Snorradottir, Vinicius Tragante, Lilja Stefansdottir, Erna V. Ivarsdottir, Gyda Bjornsdottir, Bjarni V. Halldorsson, Gudmar Thorleifsson, Bjorn R. Ludviksson, Pall T. Onundarson, Saedis Saevarsdottir, Pall Melsted, Gudmundur L. Norddahl, Unnur S. Bjornsdottir, Thorunn Olafsdottir, Daniel F. Gudbjartsson, Unnur Thorsteinsdottir, Ingileif Jonsdottir, Patrick Sulem, Kari Stefansson
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-9 (2023)
Abstract Urticaria is a skin disorder characterized by outbreaks of raised pruritic wheals. In order to identify sequence variants associated with urticaria, we performed a meta-analysis of genome-wide association studies for urticaria with a total o
Externí odkaz:
https://doaj.org/article/1e7c03c21b63437397dd6ce3465df5ca
Autor:
James Zangrilli, Liam G Heaney, Paul E Pfeffer, John Busby, Vibeke Backer, Takashi Iwanaga, Isha Chaudhry, Marjan Kerkhof, Celeste Porsbjerg, Enrico Heffler, Trung N. Tran, Mark Hew, Lakmini Bulathsinhala, Guy Brusselle, Marianna Alacqua, Todor A. Popov, Sverre Lehmann, Nikolaos G. Papadopoulos, Lauri Lehtimäki, Chris A. Price, Victoria Carter, Roland Buhl, Matthew J. Peters, Leif Bjermer, Alan Altraja, David A. Jackson, Yuji Tohda, Luis Pérez de Llano, Arnaud Bourdin, Chin Kook Rhee, Christian Taube, J. Mark FitzGerald, Mariko Siyue Koh, Unnur S. Bjornsdottir, Neva Eleangovan, Giorgio Walter Canonica, Andriana I. Papaioannou, David Price, Naeimeh Hosseini, Camille Taillé, Borja G. Cosío, Michael E. Wechsler, Mona Al-Ahmad, Mohsen Sadatsafavi, Andrew Menzies-Gow, Ruth Murray, George Christoff, Richard W. Costello, Eileen Wang
Publikováno v:
Chest. 160:814-830
Background Phenotypic characteristics of patients with eosinophilic and noneosinophilic asthma are not well characterized in global, real-life severe asthma cohorts. Research Question What is the prevalence of eosinophilic and noneosinophilic phenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::362b45fda24889570208ce0d2ca6b975
https://doi.org/10.1016/j.chest.2021.04.013
https://doi.org/10.1016/j.chest.2021.04.013
Autor:
Guy Brusselle, Victoria Carter, Liam G Heaney, Matthew J. Peters, Takashi Iwanaga, Luis Pérez de Llano, Isha Chaudhry, Celeste Porsbjerg, Lakmini Bulathsinhala, Marianna Alacqua, J. Mark FitzGerald, Anke-Hilse Maitland-van der Zee, Vicente Plaza, Yuji Tohda, Nikolaos G. Papadopoulos, Vibeke Backer, Ruth Murray, Mariko Koh Siyue, George Christoff, Neva Eleangovan, You Sook Cho, Arnaud Bourdin, Mohsen Sadatsafavi, Andrew Menzies-Gow, G. Walter Canonica, Sverre Lehmann, Chin Kook Rhee, James Zangrilli, Richard W. Costello, Rupert Jones, Leif Bjermer, Naeimeh Hosseini, Thao Le, Dora Ludviksdottir, David Price, Mark Hew, Peter G. Gibson, Elisabeth H. Bel, Enrico Heffler, Alan Altraja, Trung N. Tran, Borja G. Cosío, Lauri Lehtimäki, Chris A. Price, Unnur S. Bjornsdottir, Eileen Wang
Publikováno v:
Chest. 157:805-814
Regional and/or national severe asthma registries provide valuable country-specific information. However, they are often limited in scope within the broader definitions of severe asthma, have insufficient statistical power to answer many research que
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdffc0109ba67ea793176a9410601e03
https://doi.org/10.1016/j.chest.2019.10.051
https://doi.org/10.1016/j.chest.2019.10.051
Autor:
Bjorn R. Ludviksson, Daniel F. Gudbjartsson, Vinicius Tragante, Pall T. Onundarson, Arnaldur Gylfason, Thorarinn Gislason, Olafur A. Stefansson, Olof Sigurdardottir, Stefania Benonisdottir, Gudmundur L. Norddahl, Arna B Agustsdottir, Fannar Theodors, Bjarni V. Halldorsson, Patrick Sulem, Lilja Stefansdottir, Gardar Sveinbjornsson, Erna V. Ivarsdottir, Thorunn A. Olafsdottir, Unnur Thorsteinsdottir, Gisli Masson, Gudmar Thorleifsson, Gudmundur I. Eyjolfsson, Steinunn Guðmundsdóttir, Thorhildur Juliusdottir, David Gislason, Ingileif Jonsdottir, Jon K. Sigurdsson, Kristjan Norland, Kristbjorg Bjarnadottir, Kari Stefansson, Unnur S. Bjornsdottir, Gisli H. Halldorsson, Anna M. Kristinsdottir, Dora Ludviksdottir, Isleifur Olafsson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Publisher's version (útgefin grein)
Asthma is one of the most common chronic diseases affecting both children and adults. We report a genome-wide association meta-analysis of 69,189 cases and 702,199 controls from Iceland and UK biobank. We fin
Asthma is one of the most common chronic diseases affecting both children and adults. We report a genome-wide association meta-analysis of 69,189 cases and 702,199 controls from Iceland and UK biobank. We fin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8937da5d736ab2c1898f89a0970b406
https://doaj.org/article/9d4c023806ed4deaa904e9b46d6dc5a9
https://doaj.org/article/9d4c023806ed4deaa904e9b46d6dc5a9
Autor:
Liang-Wen Hang, Karrinda Kenny, Louis-Philippe Boulet, Jane Duke, Désirée Larenas-Linnemann, Claude S. Farah, Mónica De Gennaro, Peter A. B. Wark, Hubertus Jersmann, Maria Teresa Costantino, Dermot Ryan, Mark Hew, Vanessa M. McDonald, Mohammad Hashim Khan, Pin-Kuei Fu, Mitesh Patel, Majdy Idrees, David A. Jackson, Violina Vasileva, Constance H. Katelaris, Matthew Masoli, Nunzio Crimi, Celeste Porsbjerg, Janet Rimmer, Veronica Lawriwskyj, Ying-Chun Chien, Norma Linaker, Sally E. Wenzel, Alan Altraja, Ricardo Campos, Carlos Torres-Duque, Manlio Milanese, Enrico Heffler, Eleftherios Zervas, Andréanne Côté, Guy Brusselle, Alan James, Luis Perez-de-Llano, Jorge Maspero, David Langton, Francesca Puggioni, Mona Al-Ahmad, Riyard Al-Lehebi, Adel H. Mansur, Tom Brown, José Luis Miguel, Chris Corrigan, Arnaud Bourdin, James Fingleton, Brian J. Lipworth, Shrikant Pawar, Paula Kauppi, Philip G. Bardin, Alexandra Nanzer-Kelly, Carlos Andrés Celis-Preciado, Santus Pierachille, David Price, George Christoff, Pauline Hughes, Hitashi Rupani, João Fonseca, Nikolaos G. Papadopoulos, Naghmeh Radhakrishna, Lauri Lehtimäki, Rekha Chaudhuri, Anne-Maree Cheffins, Tara Mackenzie, Christian Taube, Kenneth R. Chapman, Charlotte Suppli Ulrik, Giorgio Walter Canonica, Mariko Koh Siyue, Maria Elisabetta Conte, Giovanna Elisiana Carpagnano, Chantal E. Le Lievre, Mohsen Sadatsafavi, Unnur S. Bjornsdottir, Praveen Akuthota, Mark FitzGerald, Andrew Menzies-Gow, Jaideep Dhariwal, Stelios Loukides, Michael E. Wechsler, Paul E Pfeffer, Matthew J. Peters, Giuseppe Guida, Zinta Harrington, Konstantinos Kostikas, Ian Clifton, Tze Lee Tan, Andriana I. Papaioannou, Li Ping Chung, John W. Upham, Parameswaran Nair, John Harrington, Aikaterini Detoraki, Liam G Heaney, Roberta Parente, Paul M. O'Byrne, Jo A Douglass, Kanok Pipatvech, Ming-Ju Tsai, Caterina Bucca, Vibeke Backer, Peter Middleton, Patrick Mitchell, Paddy Dennison, Luisa Ricciardi, Njira L Lugogo, Job F M van Boven, Flavia C.L. Hoyte, Stephen J. Fowler, Gregory Katsoulotos, Bassam Mahboub, Rovira Francisco, Nicola A. Hanania, John Corless, Mona-Rita Yacoub
Publikováno v:
Journal of Allergy and Clinical Immunology: In Practice
Journal of Allergy and Clinical Immunology: In Practice, Elsevier, 2021, ⟨10.1016/j.jaip.2021.06.041⟩
Journal of Allergy and Clinical Immunology: In Practice, Elsevier, 2021, ⟨10.1016/j.jaip.2021.06.041⟩
Background Clinicians are increasingly recognizing severe asthma patients in whom biologics and other add-on therapies lead to dramatic improvement. Currently, there is no agreed-upon super-responder (SR) definition. Objective To survey severe asthma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416ea553f71f14875689db0b55d8b3d5
https://hal.archives-ouvertes.fr/hal-03314809
https://hal.archives-ouvertes.fr/hal-03314809
Publikováno v:
The European respiratory journal. 55(5)
Environmental burden of inhaled therapies needs to be considered, as long as treatment efficacy and safety are securedhttps://bit.ly/3bRSl07
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::687648dcafe03683475827c376659b2e
https://pubmed.ncbi.nlm.nih.gov/32461340
https://pubmed.ncbi.nlm.nih.gov/32461340
Autor:
Unnur S Bjornsdottir, Stephen T Holgate, Padmalatha S Reddy, Andrew A Hill, Charlotte M McKee, Cristina I Csimma, Amy A Weaver, Holly M Legault, Clayton G Small, Renee C Ramsey, Debra K Ellis, Conor M Burke, Philip J Thompson, Peter H Howarth, Andrew J Wardlaw, Phillip G Bardin, David I Bernstein, Louis B Irving, Geoffrey L Chupp, George W Bensch, Gregory W Bensch, Jon E Stahlman, Monroe Karetzky, James W Baker, Rachel L Miller, Brad H Goodman, Donald G Raible, Samuel J Goldman, Douglas K Miller, John L Ryan, Andrew J Dorner, Frederick W Immermann, Margot O'Toole
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21902 (2011)
Asthma exacerbations remain a major unmet clinical need. The difficulty in obtaining airway tissue and bronchoalveolar lavage samples during exacerbations has greatly hampered study of naturally occurring exacerbations. This study was conducted to de
Externí odkaz:
https://doaj.org/article/f4ed057e1067408a9023f1d201f1a2b4
Autor:
Daniel F. Gudbjartsson, Hilma Holm, Olafur S. Indridason, Gudmar Thorleifsson, Vidar Edvardsson, Patrick Sulem, Femmie de Vegt, Frank C. H. d'Ancona, Martin den Heijer, Jack F. M. Wetzels, Leifur Franzson, Thorunn Rafnar, Kristleifur Kristjansson, Unnur S. Bjornsdottir, Gudmundur I. Eyjolfsson, Lambertus A. Kiemeney, Augustine Kong, Runolfur Palsson, Unnur Thorsteinsdottir, Kari Stefansson
Publikováno v:
PLoS Genetics, Vol 6, Iss 11 (2010)
Externí odkaz:
https://doaj.org/article/45eb3142c003488690941da7cf2e309a
Autor:
Karen Kapur, Toby Johnson, Noam D Beckmann, Joban Sehmi, Toshiko Tanaka, Zoltán Kutalik, Unnur Styrkarsdottir, Weihua Zhang, Diana Marek, Daniel F Gudbjartsson, Yuri Milaneschi, Hilma Holm, Angelo Diiorio, Dawn Waterworth, Yun Li, Andrew B Singleton, Unnur S Bjornsdottir, Gunnar Sigurdsson, Dena G Hernandez, Ranil Desilva, Paul Elliott, Gudmundur I Eyjolfsson, Jack M Guralnik, James Scott, Unnur Thorsteinsdottir, Stefania Bandinelli, John Chambers, Kari Stefansson, Gérard Waeber, Luigi Ferrucci, Jaspal S Kooner, Vincent Mooser, Peter Vollenweider, Jacques S Beckmann, Murielle Bochud, Sven Bergmann
Publikováno v:
PLoS Genetics, Vol 6, Iss 7, p e1001035 (2010)
Calcium has a pivotal role in biological functions, and serum calcium levels have been associated with numerous disorders of bone and mineral metabolism, as well as with cardiovascular mortality. Here we report results from a genome-wide association
Externí odkaz:
https://doaj.org/article/46b10998d61943c799ba952a26b812fa